Elwa Namagciwane TSifran. izidakamizwa yokusetshenziswa

Medicine "TSifran" kuyinto ejenti elwa namagciwane nge spectrum ezibanzi isinyathelo futhi kungokwalabo iqembu kwemithi ye fluoroquinolones. izingxenye okusebenzayo kwe umuthi ciprofloxacin futhi tinidazole. Ngenxa nokucindezela DNA gyrase futhi webhaktheriya DNA zamagama okusithiyayo, lezi izinto asebenzayo zisho asebenzayo kwezilwanyana ezincane kunazo igremu-HIV.

Ikakhulukazi, umsebenzi we isinyathelo amagciwane ekulungisweni "TSifran" imfundo manual amanothi mayelana la magciwane: Neisseriagonorrhoeae, Neisseriameningitidis, Haemophilusinfluenzae, Pseudomonasaeruginosa, Salmonellaspp, Escherichiacoli namanye amagciwane nesigqi esikhiqiza hhayi esikhiqiza penicillinase, kanye nesigqi methicillin nemithi futhi Enterococcusspp, Chlamydiaspp, Mycobacteriumspp, Legionellaspp ... amagciwane.

isinyathelo kwemithi ye nomuthi ezibanzi spectrum "TSifran" imiyalelo amagciwane ukusetshenziswa simi ngale ndlela: ". Ithuluzi senzelwe ekwelapheni pathologies ezithathelwanayo ngempumelelo ekwelapheni izinqubo ukuvuvukala - izifo okuxubile cuphuluza umsebenzi nezilwanyana ezincane aerobic kanye anaerobic lenyama".

Pharmacokinetics

Izithako ezisebenzayo zomuthi "TSifran" yokusetshenziswa libhekisela ehambisanayo kakhulu. Futhi ciprofloxacin futhi tinidazole babe ukumuncwa okuhle pheshana emathunjini.

Uma ucabangela ngamunye izithako ezisebenzayo zomuthi, kufanele kuphawulwe ukuthi ciprofloxacin has mayelana 70% bioavailability. ukumuncwa Its behlisa kancane, kuyilapho ukusetshenziswa ukudla. Lesi sidakamizwa has permeability ezinhle ku-ezicutshini futhi uketshezi lomzimba, kuhlanganise bone, imisipha, amafutha, bese uqwanga izicubu. Yena ingena phakathi kwezitho kohlelo urinary, kufaka phakathi umzimba ezifana wendlala. Kwakuyisikhathi imfihlo lembula emakamu eliphezulu okuqukethwe kiprofloksatsina, njengoba ngempela futhi isidoda, ngamathe, Bile, izindlala zamanzi uketshezi, isikhwehlela.

Tinidazole ezahlukene bioavailability ngokuphelele. Le ngxenye futhi uwela ngokushesha at lokuhlala eliphezulu kwezicubu zomzimba womuntu ketshezi Bufinyelela amaphakathi, ikakhulu cerebrospinal fluid, okuyinto bagxila kuyafana ezingeni plasma. Cishe ikota yebahlali inani izinto udle excreted ku umchamo azizange zishintshe, mayelana 10% ikhishwe ngendlela metabolites, ingxenye encane kakhulu esemazweni awuphumi e indle.

Izinkomba ngoba izidakamizwa "TSifran" yokusetshenziswa elibhekisela ekwelapheni okuxubile izinqubo ezithathelwanayo. Phakathi pathologies olucacile, ukwelapha izidakamizwa ngaphansi ukucatshangelwa esisetshenziselwa, lezi zifo ezilandelayo:

• osteomyelitis ezingamahlalakhona ;

• naphakathi-ezithathelwanayo izinqubo ukuvuvukala;

• uhudo amoebic nesihudo uhlobo exubile (amoebic futhi webhaktheriya);

• periodontitis, periostitis nezinye izifo ezithathelwanayo we ngalo ingaphakathi ngomlomo;

• izifo zabesifazane zokugula ukuvuvukala;

• sinusitis ezingamahlalakhona;

• izifo zesikhumba nezicubu ezithambile;

• isifo nasezinkingeni ezilandela ngemva kokuhlinzwa samafayela;

• wamaphaphu ithumba.

Omunye wabo, kanye nezinye izifo ezibangelwa amagciwane aerobic kanye anaerobic nozwelo isenzo yezingxenye izidakamizwa.

ukulungiselela ezamukelwe "TSifran" postprandial. Tablets okufanele zithathwe ngamanzi eziningi ezanele. iziguli Adult ngokuthatha izidakamizwa kabili ngosuku isibhebhe 500 / 600mg noma amabili 250 / 300mg. Iziguli ezingaphansi kweminyaka engu-iminyaka eyishumi nesishiyagalombili ubudala, umuthi akuyona iqondiswa. It is hhayi Kunconywa ukuba isetshenziswe abakhulelwe.

Izimo ukusetshenziswa kwezidakamizwa kuchazwe indlela yokuyelapha ukuzwela kwabaningi yezingxenye eziyingxenye tsifran pathology wegazi, porphyria.