"Lomfloks": yokusetshenziswa, intengo, analogs

Kungani umuthi ezifana "Lomfloks" angabelwa? Yokusetshenziswa, contraindications izinkomba yokwamukela zomuthi izokwethulwa ngokuningiliziwe kulesi sihloko. Ngaphezu kwalokho, kuwo uzofunda ngalokhu izidakamizwa uyatholakala, okuyinto izinto ziyingxenye ke, ukuthi kubiza malini nokuthi analogs kunoma yiluphi uhlobo.

Packaging izidakamizwa, ezakheke, incazelo kanye nokusungulwa

Ngayiphi ifomu umuthi onjalo iyatholakala ngokuthi "Lomfloks"? Yokusetshenziswa wazise ukuthi nomuthi esebenzayo is imakethwa kuphela ngesimo amaphilisi camera (ifilimu) amaphilisi oblong (400 mg) njengoba umbala brown ukukhanya.

Uphiko asebenzayo lokhu inxusa lomefloxacin (esetshenziswa njengoba hydrochloride). Ngokuphathelene izingxenye ezengeziwe, ke zihlanganisa i-lactose, talc ukuhlanzwa, isitashi, crospovidone, polyvinylpyrrolidone, sodium lauryl sulfate, propylene glycol, magnesium stearate, sodium isitashi glycolate futhi colloidal Silicon dioxide.

Ukwakheka igobolondo kuholele izinto ezilandelayo: chloride methylene, isopropanol, ama-titanium dioxide futhi hydroxypropyl methylcellulose.

"Lomfloks" kukhona izibhebhe amabhamuza (5 izingcezu) ezibekwe ku amakhadibhodi amabhokisi.

Njengoba imisebenzi izidakamizwa?

Uyini izidakamizwa "Lomfloks"? Yokusetshenziswa busikisela ukuthi leli ejenti eyisidalwa esinenkululeko zokwenziwa imithi elwa nawo. It kungokwalabo iqembu fluoroquinolone kwemithi kanye has a spectrum ebanzi isinyathelo amagciwane.

Kubhekwe umuthi okwazi ivimbela amagciwane DNA gyrase, kanjalo zakha isimiso tetramer nge eziyinkimbinkimbi yayo bese siphazamisa ukufanisana kanye nokubhalwa DNA. Ngenxa yalokho kuzichaya kukhona ukubhujiswa amaseli pathogenic.

Lokhu nomuthi iyasebenza ngokumelene igremu engemihle futhi, futhi Gram nezilwanyana ezincane omuhle futhi aerobes. Ngaphezu kwalokho, izidakamizwa nethonya elilimazayo chlamydia, isifo sofuba Mycobacterium (intra- futhi extracellularly elise), kanye nezinye izinhlobo ezimelene uroplazmy futhi mycoplasma.

Endaweni esidi kusebenta izidakamizwa is kakhulu ziyancipha, futhi kwenzeka ukungezweli kancane kakhulu.

Umuthi has a evelele nomphumela postantibioticski.

Kufanele futhi wazi ukuthi streptococci futhi anaerobes amelana isenzo lomefloxacin.

Pharmacokinetics

Kuyoze kube nini imithi ugxile "Lomfloks" (amaphilisi)? isicelo Umsebenzisi ithi ngemva kokuphathwa ku ingxenye yayo iyasebenza amuncwa umzimba cishe ngokuphelele kusukela ipheshana wokugaya ukudla.

Ngokusebenzisa mg 400 ekwakhiweni lokuhlushwa yayo eliphakeme egazini waphawula ngemva kwamahora angu-1.5-2 futhi imayelana 3,2-5,2 mg ilitha. Kufanele kuphawulwe ukuthi uma ethola nomuthi e wathi Isikali lomefloxacin lokuhlala lingadlula MIC ngoba amagciwane kakhulu. Okungenani uhhafu ngosuku.

Ukuxhumana izidakamizwa esisebenzayo plasma amaprotheni cishe 10%. Lomefloksatsin angabacwasi ngokushesha lingena kuwo wonke izicubu zomzimba. I lokuhlushwa izidakamizwa e uketshezi ababazalayo izikhathi 3-6 kunaleyo plasma, ikakhulukazi wendlala kwezicubu, iphaphu macrophage kanye nomchamo.

Impilo kwesigamu element esebenzayo cishe 7-9 amahora. Cishe 70-80% of lomefloxacin kuyinto okukhipha emini (ngefomu unmodified) umchamo.

In iziguli nge sezinso kahle umsebenzi isigamu-ukuphila kwalesi sakhi asebenzayo luyanda kakhulu.

ubufakazi

Yikuphi izifo prescribers "Lomfloks"? Yokusetshenziswa liqukethe izinkomba ezilandelayo:

• nezifo zokuphefumula (esithathelanayo), noma kunalokho, nezigaba zawo aphansi (kuhlanganise exacerbation of ukucinana kwemithambo yomoya emaphashini kanye nenyumoniya);
• zezifo ezithathelwanayo namakhambi ukuvuvukala eziye ezibangelwa amagciwane nozwelo lomefloxacin;
• abezindaba otitis;
• chlamydial chronic acute, ukutheleleka gonococcal luhlanganiswe;
• izifo eziyinkimbinkimbi futhi kube lula we urinary futhi izinhlelo zokuzala;
• izifo ezithathelwanayo kwezicubu ezithambile kanye isikhumba;
• cholecystitis kanye enterocolitis samafayela;
• izifo amalunga namathambo, kuhlanganise osteomyelitis ezingamahlalakhona;
• isifo sofuba yamaphaphu (kuhlanganise nezinhlobo acute okuqhubekayo lesi sifo, izidakamizwa amagciwane amelana, ukungabekezelelani rifampicin, isifo sofuba concomitant izinqubo nonspecific ukuvuvukala).

Phawula futhi ukuthi izidakamizwa kubhekwe evame ukunikezwa nokuvimbela yezinkinga ezithathelwanayo ngo kuhlinzwa izinqubo transurethral.

Izimo

Uma kukhona okuthile okungahambi kahle emzimbeni noma kunjalo ayikwazi ukuthatha amaphilisi "Lomfloks"? Yokusetshenziswa (intengo izidakamizwa kuyadalulwa ngezansi) iqukethe uhlu elandelayo Izimo:

• ngesikhathi sokukhulelwa futhi ibele;
• isithuthwane, ukuqina kwemithambo yegazi cerebral, kanye isimo, ephelezelwa Ukudlikizela;
• Izingane ezineminyaka engu-15;
• hypersensitivity isiguli lomefloxacin nezinye quinolones.

Nomuthi "Lomfloks": yokusetshenziswa

Incazelo leli thuluzi uhlale etholakala imiyalelo enamathiselwe. Ngaphezu kwalokho, isichasiselo izidakamizwa wazise iziguli ngalokho ulapha kufanele sithathwe emhlanganweni ukuphambuka inikezwe.

Tablets "Lomfloks" Kumelwe zigwinye (isiphuzo amanzi ekamelweni lokushisa). ukusebenza kwalo akuxhomekile ukudla. Umthamo evamile lokhu ekwakhiweni kuyinto mg 400 kanye ngosuku.

Lapho kahle izinso umsebenzi ngosuku lokuqala ukwelashwa ezinqunyiwe mg 400 izidakamizwa, kanti elandelayo - 200 mg (kanye ngosuku). Umthamo kanye nobude yokwelapha kuncike ngobucayi ukuphambuka ekhona futhi ezifweni.

Esimweni lapho isiguli sekutholakele ukuthi sine- TB amaphilisi "Lomfloks" kufanele kuhlanganiswe izidakamizwa ezifana "Isoniazid", "pyrazinamide" futhi "Ethambutol".

Ngesikhathi esifanayo kuba engathandeki kakhulu ukuthatha lomefloxacin futhi rifampicin. Lokhu kungenxa yokuthi la izinto kukhona abaphikisi ukuncintisana.

Ingozi ukusabela photochemical ingancishiswa kakhulu ngokuthatha Lomfloks amaphilisi ' "kusihlwa.

izidakamizwa ekuhlanganyeleni

Ngingakujabulela yini neminye imithi imithi "Lomfloks"? Yokusetshenziswa (esebenzisa analogue izokwethulwa ekupheleni isihloko) uthi izidakamizwa uyakwazi ukwandisa umsebenzi anticoagulants temlomo, kanye ukwandisa ubuthi ama-NSAID.

Antacids futhi sucralfate ukumuncwa kancane zomuthi futhi ukunciphisa bioavailability yayo, ukwakha kwakwakhe chelate. Ngokuphathelene reception kanyekanye probenecid, kunomthelela okusithiyayo of excretion kwezinso.

side effects

Can nomthelela ongemuhle umzimba womuntu izidakamizwa "Lomfloks"? Yokusetshenziswa (ukubuyekezwa, analogs okwethulwa kulesi sihloko) uthi ejenti ibhekwa has ohlangothini imiphumela elandelayo:

• Izikebhe inhliziyo: Vasculitis futhi acindezele ukusebenza uhlelo cardio-pulmonary.
• uhlelo zokuphefumula: edema kwamaphaphu futhi amalaka.
• Yokungezwani komzimba: komzimba nezinto, photosensitivity, anaphylaxis futhi angioedema.
• Ukugaya: nesifo pseudomembranous futhi soreness ka mucosa ngomlomo.
• Isibindi: ukuthuthukiswa zokusha kwesibindi.
• Urinary: polyuria, nephritis interstitial, nokugcinwa urinary futhi ukwehluleka kwezinso.
• Imisipha / skeleton: tendonitis, ukudabuka umsipha, arthralgia futhi myalgia.
• Isimiso sezinzwa (neuropathy kanye maphakathi): izinkathazo, ataxia, ukudideka, Ukudlikizela, ukucindezeleka, ukundindizela, izinkinga zokulala, isiyezi, nokuphazamiseka engqondweni, ubuhlungu bekhanda, ukuhhema, angaboni kahle, ukunambitheka ukuphendukezela, photophobia futhi diplopia.
• Skin: hyperpigmentation, dermatitis exfoliative, Stevens-Johnson syndrome ne epidermal necrolysis.
• Umzimba: kahle kungakhuphula izinga likashukela.
• Igazi: anaemia haemolytic futhi thrombocytopenia.

Izixwayiso

Yikuphi izici izidakamizwa kufanele bazazi iziguli, ngaphambi kokuthatha "Lomfloks" ithebhulethi? Incazelo lokulungisela imfundo edingekayo ukufunda, kanye nokubonisana kwangaphambilini nge onguchwepheshe.

Ngo leso sifo, njengoba isifo sokusha, ukulungisa of nokushintsha kokudla nokufakwa lwemithi kuyadingeka. Kodwa lokhu kuphela uma umsebenzi izinso ayiphazamiseki.

Phakathi ukwelashwa, imithi kuyadingeka bakugweme kakhulu ukuchayeka kubo UV imisebe.

Antacids, namavithamini, nezinye izinto ezithwala aqukethe aluminium, magnesium nensimbi, akufanele kuthathwe amahora amabili ngaphambi kanye amahora amabili ngemuva kokuthatha izidakamizwa ngaphansi ukucatshangelwa.

Ingabe ikhono ukushayela imoto nokuphathwa imithi by izindlela ezahlukene, "Lomfloks"? Yokusetshenziswa (intengo kwalo mkhiqizo efakwe ohlwini engxenyeni esezansi) yazisa ukuthi leli thuluzi kungabangela ukunakwa kahle futhi ngempela isiyezi. Kule ndaba, kungenzeka imisebenzi eziyingozi kufanele juqula yodwa emva ukuhlolwa impendulo lesiguli imithi.

Analogs "Lomfloks" intengo izidakamizwa Izibuyekezo

ekusetshenzisweni kwezimali nokubika Umhlahlandlela iye okwethulwa kulesi sihloko (ngezinjongo zokufundisa). Njengoba ngentengo, kungenzeka ukwazi izindleko esiqondile kuphela Pharmacy. Ngokuvamile, ngokwesilinganiso uyahluka ruble 500 (amaphilisi 5).

Yini enye ukusho mayelana izidakamizwa "Lomfloks" yokusetshenziswa? Analogue zomuthi kubhekwe ke kwezinye imininingwane. Ngokusho kwakhe, lo muthi ungase kuthathelwa indawo izidakamizwa ezilandelayo: ". Lomefloxacin hydrochloride" "Ksenakvin", "Okatsin", "Lomatsin", "maksakvin", "lomefloxacin", "Lofoks",

Njengoba for izibuyekezo, zingabantu esihle esikhathini esiningi. Iziguli bathi "Lomfloks" iphilisi ukulwa ngempela ngempumelelo ukutheleleka. Nokho, kufanele kuphawulwe ukuthi abanye abantu abathatha lesi nemithi esekhala engemihle.