Acetyl acid

Lokhu umuthi mhlawumbe edume kakhulu emhlabeni futhi nekhabethe lemithi indlu ngamunye. Acetyl acid, okubhekiselwa kuzo nangokuthi aspirin, uvele eYurophu ekhulwini XVIII. Kodwa hhayi ngesimo lapho siyibona namuhla.

Kwakuwusuku emagxolweni esihlahla esihlahleni, uyakhululwa nasePeru, lapho amaNdiya babephathwa ekhaya imfiva. igama Indian "Kin-isihlobo" kwaba, ngokusobala, kunzima ukubiza ngokuba isakhamuzi aseYurophu, futhi "esiseduze-isihlobo" iqanjwe kabusha "quinine". Iqolo zigaywa zibe impuphu kanye esetshenziselwa imfiva. Izindleko imithi kwaba ngendlela emangalisayo okusezingeni eliphezulu, ngakho waqala ukubheka okunye.

Ngo 1850th salicylic acid ahlukanisa kusukela willow (ngenhlanhla willow Latin - "salix"). Kodwa izidakamizwa kwakubiza kakhulu. Nalapha waqala ukufuna esikhundleni. Kwatholakala ukuthi acid kuqukethwe omunye ehlathini - uSpiro. Futhi isamba kakhulu kwalokho engiye willow. Kodwa lehlukanisa lwamafinyila wacasuka kakhulu futhi ukungenisa akuzona bufaneleke ikakhulukazi. Umlando buthule, abenyukela umbono ukuxhuma kwi-etholwe izidakamizwa acetyl (ETHYL) olukhulu. Igama elithi "aspirin" ubeke phansi uhlamvu lokuqala igama elithi "acetyl" kanye impande kwesihlahla igama "-spir-". Industrial ukukhiqizwa phenol, aspirin kwaqala ngo 1893.

Ayikho imithi ngeke kuqhathaniswe ungabuqeda nge aspirin okuyimpikiswano ivolumu: e-US yathela amathani angaba yizinkulungwane 12 ngonyaka.! Pharmacy yethu eyaziwa njenge-aspirin, acetylsalicylic acid, kodwa ekwakhiweni ekhiqizwa amafemu esehlukile ngaphansi amagama 60.

Acid Ekuqaleni acetyl isicelo kuphela ukwehlisa izinga lokushisa.

Long yokusesha analgesics, nonsteroidal antiinflammatory kanye ejenti antipyretic nge nokucindezela prostaglandin zamagama isayensi wabuya ku-aspirin. Acetyl acid, kanye nemithi emisha ( "Phenylbutazone" "ibuprofen", "Indomethacin", "Ketoprofen", "Ortofen" "piroxicam" niflumic acid njalo njalo., Ifa lezi zimfanelo. Aspirin lapha yayingeyinhle lezi, kodwa akukho imithi ngeke kuqhathaniswe naye yizinhlobonhlobo ukuthuthukisa umphumela analgesic, wanquma ukwenza inhlanganisela yemithi, lapho isisekelo kuyoba zonke aspirin efanayo: ". Asfen", "askofen", "Kofetsil", "Tsitramon", "sedalgin" (a esebenzayo ngaphezulu ).

Acetyl acid ukuthi tacitly unikezwa elinye igama - acetic acid. Amandla ayo ayigcini ukukhululeka ubuhlungu kanye nokuncipha lokushisa. Ngemithamo ongaphakeme ke uyakwazi mncane igazi. Ngakho kwakucatshangwa kuze muva nje. Nokho, ukukhanya yezokwelapha emva ucwaningo lwamuva aseqalile ukungabaza: ke aspirin ayinangozi empeleni? Yena thins igazi, kodwa ngesikhathi esifanayo ukuvimba ukususwa slag (udoti) kusuka emzimbeni wethu. Non-steroidal izidakamizwa ukuvuvukala ( "Analgin", "ibuprofen" "paracetamol", "aspirin", njll) Nweba kwezinso efferent arteriole, ekunciphiseni ekugcineni inani umchamo kwakhiwa. It uthola uketshezi olunqwabelene ukuthi uphoqelekile ukuba asuse umzimba, kodwa-ke yakhiwa kwagcizelela, "eziphuthumayo" nezindlala umjuluko, "wethula" nge ketshezi nokushisa. Sithola nomphumela ofanayo, futhi okuyiwona sesiwathethe aspirin. On inkinga ngeke ukukhuluma, uma kuphela nezindlala umjuluko can okukhipha esilinganayo wobuthi nezinso. Kodwa Ingcenye eqakathekileko yomsebenzi wehlelo slag emafektri okugqilazwa umphumela namanje uhlala kithi, okuholela ekugcineni kokunqotshwa kwezitho zangaphakathi. Nokho, akufanele siphele amandla lokhu kahle aspirin kuphela. Ngokufanayo, uyokwenza ajwayelekile kithi, futhi lime, futhi "Kalinka Malinka," kanye nezinye izindlela "kagogo". Iphuzu lapha yilona olunzulu emsebenzini kumasweatshop nezindlala futhi umphumela okwalandela.

Uwuchaze ibinzana elikhulu: ebambe Imininingwane ophethe impilo. Acetyl acid, kusuka noma yini ungazange usebenzise (antipyretic, analgesic noma "ndawonye"), kumele kusetshenziswe ngokuqapha okukhulu kanye kuphela iseluleko owelapha.