"Felodip": yokusetshenziswa, ukubuyekezwa. izidakamizwa analogue

Okubizela lesi sidakamizwa "Felodip"? Yokusetshenziswa zomuthi uzobe wachaza ngokuningiliziwe esihlokweni ethulwa. Futhi kuyo, uyofunda ngalokho lokhu izidakamizwa inikezwa, yini imiphumela engemihle it has, noma ngabe lokhu Izimo izidakamizwa, ukuthi kubiza malini, esesikhundleni analogue nokunye.

Ukwakheka izidakamizwa, uhlobo ezokukhiqiza kanye emaphaketheni

Ngayiphi ifomu zingatholakala ekhemisi izidakamizwa "Felodip"? ekusetshenzisweni lo mhlahlandlela imithi Lithi itholakala kuphela ngesimo amaphilisi nge senzo isikhathi eside. Ngaphezu kwalokho, amazinga okukhishwa ezahlukene zomuthi has a imvilophi ezahlukene:

• amaphilisi aphuzi ngesimo udali, ngaphandle iphunga okhonjiswe inombolo 2.5. Isici esebenzayo ezifana izidakamizwa felodipine eziphatha inani 2.5 mg. Excipients zomuthi kukhona monohydrate lactose, hypromellose, microcrystalline cellulose, obomvu yensimbi oxide, povidone, ama-titanium dioxide, gallate propyl, ophuzi yensimbi oxide, magnesium stearate, propylene glycol, anhydrous Silica colloidal, talc. Ngo ukudayiswa izidakamizwa esebenzayo engena ibhamuza amaphilisi angu-10 ezibekwe amakhadibhodi amabhokisi.
• Izibhebhe ukukhanya color pink esime udali, ngaphandle iphunga okhonjiswe inombolo 5. Uphiko asebenzayo sokulungiselela enjalo kuphuma felodipine e isamba 5 mg. Excipients zomuthi aphume ashone monohydrate lactose, hypromellose, microcrystalline cellulose, obomvu yensimbi oxide, povidone, ama-titanium dioxide, gallate propyl, ophuzi yensimbi oxide, magnesium stearate, propylene glycol, anhydrous Silica colloidal, talc. Ngo ukudayiswa izidakamizwa esebenzayo engena ibhamuza amaphilisi 10, ezibekwe ku amakhadibhodi amabhokisi.
• Tablets ngokubomvu nesitshulu brown ezimise ngaphandle iphunga esiqokiwe inani 10. I element asebenzayo we izenzo ezinjalo izidakamizwa felodipine e isamba 10 mg. Nezinsizasenzo kukhona monohydrate lactose, hypromellose, microcrystalline cellulose, obomvu yensimbi oxide, povidone, ama-titanium dioxide, gallate propyl, ophuzi yensimbi oxide, magnesium stearate, propylene glycol, anhydrous Silica colloidal, talc. Ngo ukudayiswa izidakamizwa esebenzayo engena ibhamuza amaphilisi 10. Amashashaza ibekwe ku amakhadibhodi amabhokisi.

I izakhiwo kwemithi zomuthi

Kuyini idivayisi wezokwelapha "Felodip"? Yokusetshenziswa zomuthi uthi kuyinto-calcium channel blocker kancane. izidakamizwa Okubukwe kungokwalabo iqembu dihydropyridine.

Lo muthi unamandla abazikhandla imiphumela antianginal futhi antihypertensive. Ngaphezu kwalokho, kunciphisa ingcindezi (igazi) ngokunciphisa inani neuropathy ukumelana semithambo.

Yini nezinye izakhiwo babe izidakamizwa "Felodip"? Yokusetshenziswa ekulungisweni phakathi ulwazi anazo nomphumela umthamo ancike anti-ischemic. Imithi kunciphisa usayizi infarction, futhi ivikela umzimba emirarweni reperfusion.

Leli thuluzi likwazi nhlobo nomphumela omubi inotropic. It has a nomthelela othize uhlelo Umqhubi.

I pharmacokinetics zomuthi

Kuyoze kube nini le izidakamizwa amuncwa umzimba, "Felodip"? Yokusetshenziswa, lemibono kusho ukunikeza ukuthi ngemva umthamo nomuthi ku ketshezi asebenzayo amuncwa umzimba cishe ngokuphelele kusukela ipheshana yesisu futhi izenzo ngokushesha. Ngenxa ngomthamo ifomu yayo, ukukhululwa imisiwe timphawu asebenzayo kuqinisekisa lokuhlushwa yayo iyunifomu egazini (ngaphakathi ngosuku), futhi kuholela ekwandeni esigabeni ukumuncwa.

Asinakusho ukuthi bioavailability zomuthi akuxhomekile umthamo zokwelapha futhi cishe 15%.

Sesibopho ukuthobisa plasma amaprotheni ngokunembile ngayo cishe 99%. I nomuthi ikhishwe kanye nobisi lwebele futhi lingena kusivimbeli gazi ebuchosheni futhi umgoqo esinomhlapho. Ngekusetjentiswa isikhathi eside we ketshezi esebenzayo kungekho ekuqongeleleni kwenzeka.

Lapho izidakamizwa akheka "Felodip"? Isithako asebenzayo lokhu inxusa akheka esibindini. Kuleli fomu metabolites esingasebenzi.

Ingxenye-ukuphila zomuthi imayelana 25 amahora. ukulungiselela asibonisa ngokulibeka metabolites (cishe 70%) umchamo kanye endleni (30%).

izinkomba nomuthi

Kwezinye izimo, isiguli ezinqunyiwe imithi "Felodip" (5 mg) Imiyalelo lokhu imithi iqukethe uhlu elandelayo izinkomba ukusetshenziswa:

• nomfutho wegazi ophezulu;
• angina;
• arrhythmia;
• isifo senhliziyo,
• iziyaluyalu kwegazi;
• Raynaud Syndrome.

Izimo izidakamizwa

Kukuyiphi amacala akuvunyelwe nhlobo ukuthatha imithi "Felodip"? Uphenyo odokotela, kanye imiyalelo elikulesi sihloko sisho futhi ukuthi izidakamizwa akufanele isetshenziswe ngaphansi kwale mibandela elandelayo:

• acute isilethikusebenza, kanye enyangeni eyodwa emva esivimba amanzi;
• angina engazinzile;
• ukushaqeka cardiogenic;
• ukumelwa inhliziyo, ikakhulukazi decompensated;
• stenosis yomthambo i-aorta (isifo abalulekile);
• ukhulelwe;
• hypotension (esibi kakhulu);
• ezinganeni kanye intsha (eneminyaka engaphansi kwengu-18);
• ngesikhathi lactation;
• ukuzwela anda isiguli izidakamizwa noma ezinye nemikhiqizo dihydropyridine.

Omunye akufanele sikhohlwe ukuthi leli thuluzi ngokucophelela okukhulu ebekiwe iziguli esingamahlalakhona hepatic futhi kwezinso.

kudivayisi Yezokwelapha 'Felodip ": yokusetshenziswa

Analogue kwaleli thuluzi izokwethulwa kancane okunye. Manje ngifuna ukunitshela ukuthi imithi kumele ithathwe ngendlela efanele.

Lapho umfutho wegazi ophakeme umthamo abadala kanye nabantu abadala isethwe ngamunye. Ngokuvamile, lemali sokuqala umuthi 5 mg kanye ngelanga. Phakathi Ukukhetha iziguli ezifanele umthamo Kunconywa ukusebenzisa esibhebheni 2.5 mg. Lapho esiphuthumayo kudingeka ukwandisa umthamo imithi kungaba. Umqulu isilinganiso nomuthi wokwelapha nokugcinwa 5-10 mg ngosuku.

Ukuze ezigulini esezikhulile noma iziguli eziphathwa kahle isibindi umsebenzi ekuqaleni kuka ukwelashwa iqondiswa e isamba 2.5 mg ngosuku.

Ngo esitebeleni imithi angina "Felodip" okunqunyiwe ngamunye. Ngakho umthamo yayo sokuqala (abadala) 5 mg kanye ngelanga. Uma kudingeka, umthamo kungenziwa lenyuke-10 mg ngosuku. Umkhawulo lemali nsuku zonke izidakamizwa 20 mg.

Tablets "Felodip" kuvunyelwe ukuthatha lihambisana ACE inhibitor, beta-blocker futhi isisu. Nokho, kufanele kuphawulwe ukuthi ngenkathi umphumela hypotensive buyathuthuka. Ngakho-ke kumelwe niqaphelisise ngenxa kwengozi hypotension.

In iziguli nge kanzima kahle isibindi umsebenzi umthamo imithi kumele kungancipha.

Zilethwa izidakamizwa kumele kuthathwe ekuseni kakhulu ngaphambi kokudla kwasekuseni. Kulokhu, ithebhulethi noma kunjalo akunakwenzeka ukwambula, wathatheka noma ukuhlukana.

izindlela ukweqisa izidakamizwa

ukusetshenziswa engalungile amaphilisi "Felodip" izimpawu ezilandelayo ukweqisa izidakamizwa kungenzeka ezigulini: bradycardia futhi hypotension (esibi kakhulu).

Endabeni ka okuvela izimpawu ezifana yokwelapha lingaze. Uma hypotension (esibi kakhulu) iziguli ukunikeza isikhundla evundla phakamisa imilenze. Mayelana bradycardia, kuleso simo atropine nesineke intramuscularly iqondiswa ngesikhathi umthamo 0.5-1 mg. Uma kudingekile, ukuze wandise ivolumu plasma ukumnika Kwenziwa sodium chloride, isixazululo glucose noma dextran.

Lapho ngenhla echazwe nokungasebenzi izinyathelo ezinqunyiwe imithi isiguli umphumela oqavile ku-receptor-alpha-adrenergic.

Imiphumela engemihle evela ngokuthatha izidakamizwa

Can nomthelela ongemuhle umzimba womuntu ukuphuza umuthi "Felodip"? Analogue kwaleli thuluzi bese ukulungiselela ngokwayo kuvame ukubangela ikhanda, ngamanzi ebusweni, isiyezi, palpitations nokukhathala. Nokho, kufanele kuphawulwe ukuthi ukusabela okunjalo kukhona emuva. Ngokuvamile avele ekuqaleni ukwelashwa, kanye ngokwandisa umthamo zomuthi.

By the way, kuye ngokuthi lemali wathola imithi isiguli angavela edema neuropathy. Ngokusho kochwepheshe, zingabantu umphumela vasodilation precapillary.

In iziguli periodontal noma isifo sezinsini ezigulini ethola izidakamizwa kungaba ukuvuvukala elincane izinsini. Le nqubo kungagwenywa, uma nigcina obuphelele inhlanzeko yomlomo.

Kwezinye izimo sisuke sicabanga kokuthola imithi iba imbangela okulandelayo side effects:

• Isimiso senhliziyo nemithambo yegazi: palpitations, tachycardia, futhi edema neuropathy.
• ukusabela dermatological: photosensitivity, pruritus, urticaria.
• Neuropathy futhi uqondiswe isimiso sezinzwa esiyinhloko: paresthesia, ikhanda nesiyezi.
• uhlelo zemisipha: arthralgia, myalgia.
• ipheshana wokugaya ukudla: Hyperplasia gingival, isicanucanu, ukwanda enzyme isibindi.
• Umphumela: ukukhathala, hypersensitivity ukusabela, kuhlanganise angioedema.

Analogs, futhi izindleko zomuthi

Yeka ukuthi kuyinto imithi phambi kwethu? Lokho impikiswano eyaphakanyiswa iziguli eziningi othola lokhu imishanguzo ayilawulwa. Kufanele kuqashelwe ukuthi namuhla imithi angathengwa at amanani alandelayo:

• Izibhebhe 2.5 mg (30 izingcezu) - 425 ruble Russian;
• izibhebhe volume of 5 mg (30 izingcezu) - 556 ruble Russian;
• amaphilisi ngendlela ivolumu mg 10 (30 izingcezu) - 831 ruble Russian.

Yini esikhundleni izidakamizwa "Felodip"? Analogs yalesi izidakamizwa ayatholakala cishe kuzo zonke ekhemisi. Phakathi kwabo, ngithole sifuna ukugqamisa imithi ezilandelayo:. "Plendil," "Felodipine-NW", "Felodipine" futhi "Felotenz kuthiye ukukhula"

okubuyayo ezigulini mayelana nomkhiqizo okwelapha

Nobufakazi mayelana "Felodip" isimo nokulungiselela ukuthi kuyaphumelela kakhulu futhi kahle ikubekezelele iziguli, kungakhathaliseki ubudala nobulili. Ngaphezu kwalokho, kungenzeka izidakamizwa esebenzayo kuthathwe ngisho by iziguli sikashukela, izinkinga kwezinso, esifubeni somoya nezinye izifo zamaphaphu obstructive nge Raynaud Syndrome, hyperlipidemia, sifo, futhi ngemva wamaphaphu ukufakelwa.

Ochwepheshe abaningi aveze yokuthi umuthi akunamthelela iphrofayli lipid kanye igazi glucose okuhlushwa.

Izibuyekezo ezingezinhle

Phakathi Izibuyekezo ezingezinhle ukuthi ushiye iziguli kulo muthi, singabona kulabo abahlobene izindleko eziphakeme izidakamizwa. Nakuba kunodokotela baphikisa ngokuthi intengo yayo okuhambisana ngokugcwele ukusebenza kahle kanye izinga.