"Glutoxim": yokusetshenziswa, ngempela

Asho izidakamizwa "Glutoxim"? Yokusetshenziswa kwaleli thuluzi izokwethulwa esihlokweni. Futhi, uyofunda ngalokho lokhu Izimo izidakamizwa babe amafomu lapho kukhiqizwa, kangakanani, uma kwadingeka iyiphi analogue nokunye.

Ifomu ukukhululwa izidakamizwa

Ngayiphi Lelifomu liyatholakala ekhelini izidakamizwa "Glutoxim"? Leli thuluzi kungatholakala kuphela ekhemisi njengoba isixazululo ecacile, okuyinto senzelwe umjovo. It has no iphunga noma umbala phama ampoule elilodwa noma amabili mg.

Ukwakheka izidakamizwa

I nomuthi "Glutoxim" imfundo manual ukuthi inikezwe ikhithi yakhiwa izakhi asebenzayo ezifana bis- (gamma-L-glutamyl) -L-cysteinyl-bis-glycine disodium usawoti. Ngaphezu kwalokho, i-nomuthi kuhlanganisa kanye izithako asizayo ngo ifomu sodium acetate, acetic acid namanzi umjovo. Eqinisweni, wathi izidakamizwa inhlanganisela disodium nosawoti nama-amino acid amathathu ahlukene (cysteine, glycine, futhi glutamine).

okuhlushwa izindlela

Ubuningi yezingxenye noma nomuthi zingase zihluke.

• Isixazululo "Glutoxim" 1 ngemililitha iqukethe-10% isithako esebenzayo.
• Isixazululo kuhlanganisa 0.5% 5 namamililitha isithako esebenzayo.
• Isixazululo "Glutoxim" 3 namamililitha eliqukethe u-30% isithako esebenzayo.

Lapho uvula isitsha esuka imithi zifike ngephunga ukukhanya acetic acid. Zuza nomuthi ezinjalo kungenzeka, ngaphatha ibhokisi elinezincwadi 10 noma 5 ampoules ngaphakathi.

I izakhiwo kwemithi zomuthi

Medicine "Glutoxim" limelela umenzeli immunomodulatory okuhloswe ngalo ukuthuthukisa amasosha omzimba womuntu. Kwasheshe sivuselela receptor cell, kanye ukuzwela kwabo izakhi zokulawula. Ngaphezu kwalokho, ukusetshenziswa asebenzayo aziveza tsitotropny umphumela evelele.

Ngemuva kwesicelo we nomuthi ke uyakwazi ukwandisa ukukhiqizwa zonke izinhlobo zamangqamuzana banesibopho impendulo non-ethize mzimba. Ngaphezu kwalokho, izidakamizwa esheshisa inqubo kumiswa lama-lymphocyte, erythrocyte, granulocytes (monocytes) kanye hematopoiesis e umnkantsha.

Yiziphi ezinye izidakamizwa anezakhi "Glutoxim"? Izibuyekezo ochwepheshe aqukethe ulwazi oluningi mayelana nokuthi lokhu izidakamizwa uyakwazi ukwenza ngcono isimo lesiguli. Phela, kulula ukuba kusebenze izinqubo phagocytosis nezicubu macrophage. Umuthi kuzole segazi futhi kwandisa inani lamaseli e-ke, kuvusa okuwuphawu izinhlelo ukuthi banesibopho ukuzivikela komzimba.

nomuthi wathi uyakwazi ukuqalisa ukukhiqizwa cytokine (ngamanye amazwi, ama-hormone izicubu), interferon, tumor necrosis factor, eklanyelwe ulwe kumiswa amangqamuzana omdlavuza womuntu, futhi hormone i-erythropoietin ukuthi ukusheshisa izinqubo ukukhiqizwa erythrocyte umnkantsha.

Pharmacokinetics zomuthi

Ngemva kokuphathwa esicutshini, emthanjeni noma ongama le bioavailability zomuthi ifinyelela amaphesenti angu-90. Lokho 10 amaphesenti isithako esebenzayo hhayi amuncwa umzimba womuntu exoshwa. Kukhona kwencika komugqa lokuhlushwa izidakamizwa e emakamu igazi yesixazululo esetshenziswa.

ekuphathweni esicutshini ukulungiswa lokuhlushwa wobuningi kufinyelelwa emva kwemizuzu eziyisikhombisa kuya kweziyishumi, futhi phakathi emthanjeni - imizuzu amabili kuya kwamahlanu.

Lokhu nomuthi is akheka e kwezitho nezicubu zomzimba, kanye imikhiqizo yayo kwamazinyo etholakala kuphela nezinso.

Izinkomba ukusetshenziswa kwemithi

Kwezinye izimo, isiguli ezinqunyiwe imithi "Glutoxim"? ku isicelo yomhlahlandlela ithuluzi iqukethe uhlu olude izinkomba ukusetshenziswa kwaso. Ake sixoxe ngazo ngokuningiliziwe.

• Umuthi wathi ngokuvamile sisetshenziswa yokwelapha kanye nokuvimbela yesibili immunodeficiency uthi. Ngokuvamile, basuke kubangelwa izifo ezahlukene, kanye amakhemikhali nemisebe izici.
• Odokotela kungaba aqoke izidakamizwa "Glutoxim" ukuze sikhuthaze umnkantsha. Phela, lingelikaJehova ingxenye esebenzayo uhileleke ngokuqondile e obusekela abajwayelekile igazi ifomula.
• Uma isiguli sekutholakele ukuthi sine- isibindi izifo ezithathelwanayo (isb ukusha kwesibindi kohlobo B, C noma D), khona-ke umuthi onjalo isetshenziswa njengophawu hepatoprotective ezinhle (isibindi umvikeli).
• Esimweni lapho isiguli ezingamahlalakhona obstructive isifo samaphaphu, le nomuthi "Glutoxim" isetshenziselwa ukuthuthukisa umphumela izidakamizwa ama-hormone nemithi elwa namagciwane.

Yini nezinye Izinguquko kungenzeka yokuthi udokotela ekunika imithi "Glutoxim"? Ukufundiswa uthi izinkomba ukusetshenziswa zomuthi kungenzeka izimo zezokwelapha ezilandelayo:

• Ngemva kokwenza ithuluzi ukusebenza esetshenziswa nokuvimbela ukuvuvukala.
• Phakathi ukwelashwa TB umuthi ephumelela kakhulu ifomu eqonda lesi sifo, kanye nganoma ukuzwela eliphansi pathogen kuya ejenti-antibiotic futhi zikhuthaza omzimba isiguli.
• Isikhathi esining impela zisebenzisa imithi "Glutoxim" nokuvimbela exacerbations zokusha kwesibindi. Njengomthetho, kwenzeka ngesikhathi ukwelashwa elwa ne-TB.
• Umuthi wathi buyindlela ephumelelayo ukuthi sisetshenziswa kabanzi ukuze silwe ukudakwa. Yingakho-ke kungenziwa ebekiwe ukunciphisa imiphumela anobuthi ngamakhemikhali kwesibindi kanye nezinye izitho zangaphakathi.
• Phakathi umdlavuza imithi yokwelapha isetshenziswa ukubuyisela umsebenzi hematopoietic ka umnkantsha. ukusetshenziswa kwabo kusiza ukunqoba imiphumela emibi yokwelashwa, ezifana ukukhathala okusezingeni eliphezulu, ukuntuleka kwegazi emzimbeni, ukungakuthandi ukudla, kanye nokuzwela anda ukuze ubuhlungu.

Asinakusho ukuthi ezimweni ezingavamile, isiguli angabelwa ukuba umuthi "Glutoxim" e-psoriasis. Izibuyekezo ngalokhu izidakamizwa ogxile omuhle.

Izimo ukusetshenziswa imithi

Kwezinye izimo, it is hhayi Kunconywa ukusebenzisa izidakamizwa "Glutoxim"? ku isicelo yomhlahlandlela ithuluzi uthi akufanele enqunywe wumgomo, uma isiguli ine isici esiyingqayizivele yezingxenye izidakamizwa.

Kufanele ukuthi isifundo ku yokwamukela izidakamizwa phakathi nokukhulelwa kanye lactation ungazange sezenziwe. Yingakho kulezi zimo, abesifazane belulekwa ukuba uyeka ukuyisebenzisa.

Nomuthi "Glutoxim": yokusetshenziswa

Kubantu abadala, umthamo le-ejenti kumele tisukele angu-5 kuya ku-40 nsuku zonke. Lokhu kungase kusetshenziswe esicutshini, ongama nemizila emthanjeni yokuphathwa. Umthamo esimweni ngasinye ukhetha udokotela kuphela.

• Ukuze kuliwe izici kwezemvelo okunomthelela omubi kakhulu, kanye izinyathelo zokuvimbela emva kokuhlinzwa izidakamizwa kunikezwa endaweni umthamo 5-10 mg nsuku zonke kwaze kwaphela amasonto 2-4.
• Phakathi ekwelapheni ukuvuvukala uhlelo urogenital namaphaphu, kanye nokungezwani komzimba nezinto, umuthi isetshenziswa inani 5-40 angu ngosuku. Inkambo yokwelashwa singemaviki lange 2-3.
• Lapho ukwelashwa kwe-TB i-nomuthi isetshenziswa umthamo angu-60 ngosuku ngemithamo ezimbili ihlukaniswe. Ubude besikhathi sokwelashwa - 2 izinyanga. Uma isifo ingena esigabeni elikhiqizayo, kunikezelwe umthamo 10-20 mg kabili ngosuku, katsatfu ngeliviki. Ukuba yokwelapha wachitha, kufanele wenze ikhefu izinyanga 2-6.
• Ngo-psoriasis nangesineke kungase esizosingathwa 10 mg ukulungiselela (intramuscularly). Ukwelashwa okufanele kwenziwe nsuku zonke izinsuku ezingu-14. Ngemva kwalokho, phakathi nalezi zinsuku 35 imithi zisebenzisa kabili ngesonto ngesikhathi umthamo 10 angu. Uma kwenziwa ayinzima yokwelapha psoriasis, le nomuthi iqondiswa e umthamo 10 angu ngosuku izinsuku ezingu-10.
• Lapho imiphumela emibi yokwelashwa ngamakhemikhali nemisebe yokwelapha ephelezelwa antitoxic nomuthi esetshenziswa phansi kwesikhumba e imali angu-60. Uma lokhu kulungiselelwa ezinqunyiwe amahora 2 ngaphambi inqubo, bese kabili ngesonto umthamo ofanayo. Umuthi isetshenziswa ngesikhathi ngelashwa nangemithi ngamunye.
• Ukuze ukuvimbela izifo ezithathelwanayo izidakamizwa is ekunike lokuyofunda amasonto amabili 5-10 angu.

Kufanele wakhumbula ukuthi, kwezokuphatha emthanjeni isetshenziselwe singamaphesenti angu 5 isixazululo glucose noma nosawoti bokuphila.

Izici imithi

Yini umbono olwabiwa iziguli mayelana izidakamizwa 'Glutoxim "? Izibuyekezo zihlukile. Amanye amadoda abamiswe le imithi ukwelapha izinso izifo, saphawula ukuthi leli gama kuthuthukisa bavukelwe. Ochwepheshe baye babonisa ukuthi lokhu kusho kwandziswa kwelinani letikhungo isidoda bukhoma isidoda, kanye kunciphisa kobukhulu side effects emva ukusetshenziswa ejenti antibiotic. Ngaphezu kwalokho, lokhu izidakamizwa uyakwazi ngcono ukusebenza izidakamizwa elwa namagciwane, okungokwendlela uchungechunge quinolone ( "Ofloxacin", "Oxolinic acid", "Norfloxacin" futhi "Tsiklofloksatsin").

Lesi sidakamizwa ngesivinini ukuthethelelwa ngesikhathi yokwelapha of isifo sezinso. Ukusetshenziswa Its iyehlisa imvamisa umuntu uyahluleka uma elwa, kuze yokuqothulwa yabo.

Ochwepheshe bezifo, le nomuthi "Glutoxim" siyasebenza kakhulu ekwelapheni prostatitis okungamahlalakhona, kanye nezifo ezithathelwanayo, ezithathelwana ngobulili.

Side Effects "Glutoxim" izidakamizwa

Ukusetshenziswa leli thuluzi kufanele kulawulwa udokotela, naphezu kweqiniso lokuthi izidakamizwa akanawo inombolo enkulu yemiphumela emibi. Ukuze esicutshini noma abaphathi ongama ku lokushisa komzimba lesiguli kuze kube 37.5 degrees singenzeka. Kodwa lena kuphela ngaphansi kwesimo sokuthi, uma isiguli ine isici esiyingqayizivele yezingxenye.

Ukusebenzisa izidakamizwa izingane

Kungenzeka yini ukwenza imijovo "Glutoxim" izingane? Yiqiniso, yebo. Kodwa lokhu kuphela uma nezinye izidakamizwa yayingasizi.

Ngokuphathelene kwenkululeko isicelo se-nomuthi "Glutoxim" Isikali izingane ibalwa ngesisekelo isisindo (2.5-5 angu kilogram per). Ngakho isidakamizwa kungenzeka iqondiswa intramuscularly, ngemithambo yegazi noma phansi kwesikhumba.

Phakathi ukwelashwa of izinso izifo izingane nentsha ukusetshenziswa kwalesi izidakamizwa lihlotshaniswa kusebenta encishisiwe kwamaphilisi kanye hormone. ubufakazi Medical esibonisa ukuthi ukusetshenziswa kwalesi imithi ngesivinini ukuqala ukuthethelelwa, kanye ngcono isimo jikelele iziguli, nge akunamthelela ukubala igazi.

Ukuxoxa utshwala nezinye izidakamizwa

Ngaphezu kwalokho ukuthuthukisa isenzo quinolone ejenti-antibiotic uchungechunge ekuxhumaneni nezinye izidakamizwa aye atholakala. Ngokuphathelene utshwala, unikezwa hepatoprotective izakhiwo, lokhu izidakamizwa kunciphisa umthelela ongemuhle utshwala ngesikhathi kwenzeka lokhu isibindi kanye nezinso. Ngakho-ke ngesivinini noqhekeko utshwala egazini.

Analogue yentengo izidakamizwa

Kungakanani kuthiwa nomuthi? Kufanele kuqashelwe ukuthi intengo yale izidakamizwa impela high. Ngakho, ampoules for 5 1 amaphesenti isixazululo (2 ml), une ukunikeza ruble 1600. Kepha isixazululo amaphesenti-3, kuyafaneleka ezibizayo nakakhulu - ruble mayelana 2000.

Kuthiwani uma ungenayo imali eyanele yokuthenga izidakamizwa "Glutoxim"? Analogs kungaba ishibhile. Phakathi kungenzeka leyo mithi okukhulunywe okulandelayo: "Vironel", "Amiksin IP", "Bioleykin", "Lavomax", "Avonex", "Anaferon", "Alfiron", "Galavit", "Viferon" "Echinacea kompozitum", " Immunoflazidum "," bromide azoximer "," Septilin "," Roncoleukin "," Protfenolozid "," Granocyte "," Imunorm "nabanye.

Kufanele kugcizelelwe ukuthi ngamunye imithi ethulwa has ukusetshenziswa ayo ethize. Noma kunjalo, konke banayo emzimbeni womuntu imayelana nomphumela ofanayo.

Izibuyekezo ochwepheshe ngemithi

Ngokwe-odokotela, ngesikhathi izidakamizwa nokwelashwa ngamakhemikhali uyakwazi ngokushesha unekhemikhali bonke ubuthi kukuthinta ngokuqondile isimo jikelele iziguli. Ngaphezu kwalokho, ezinye izazi baphikisa ngokuthi izidakamizwa "Glutoxim" kuhle kakhulu ekwelapheni izifo ezithathelwanayo, ikakhulukazi ukucinana kwemigudu yokuphefumula. It usebenza immunomodulator ngempumelelo futhi ngokushesha, ukunciphisa isikhathi sokwelashwa by cishe ingxenye yesithathu.

nobufakazi

Iziguli wake ukusebenzisa izidakamizwa ngemva nokwelashwa ngamakhemikhali, uqaphele ukuthi, uma kuqhathaniswa nabangu-course yokuqala, lapho leli thuluzi ingakamiswa esimisiwe, isimo uye atjhaphuluke khudlwana. Ngesikhathi esifanayo wanyamalala ngokuphelele ukunambitheka kanye kome nolwelwesi lwamafinyila. ubuthongo Futhi, iziguli ngcono kakhulu, kwathatha izinkathazo evamile, okuyinto eyenzeka njalo emva kokuphothulwa ngamakhemikhali ukwelashwa.

Labo ezigulini babekade bemiswe izidakamizwa "Glutoxim" ekwelapheni umdlavuza wendlala yabesilisa, bathi yi ebucayi. Ukukhula izimila behlisa nokuvuvukala kwaqala ukuncipha.

Iziguli kwathiwa unesifo "sofuba" futhi ukhulume mayelana ukuphumelela imithi. Ngokusho izimpendulo zabo, ukwelapha lesi sifo ngokushesha futhi zikhululekile. Iziguli walulama evamile kakhulu segazi, izimpawu zokudakwa zinyamalale, futhi kuthuthukisa ubuthongo futhi zinyamalale ukunambitheka ezingemnandi ababayo emlonyeni, kome nolwelwesi lwamafinyila.

Imininingwane engeziwe mayelana nemithi

Njengamanje, isenzo wathi ucwaningo izidakamizwa emzimbeni womuntu uyaqhubeka. Imiyalelo, okuyinto unamathele izidakamizwa, kukhona izindlela wafunda kakhulu ukuphuza imithi. Kunobufakazi ukusebenza kwalo ekwelapheni izifo ezithathelwanayo, kuhlanganise nalezo ezingasebenzisi adluliswa ngokocansi kanye ne-hepatitis ahlukahlukene, izimila nezinye kwezinso.

Impilo eshalofini zomuthi kanye nemibandela isitoreji

Kuphi futhi kanjani ukugcina imithi "Glutoxim"? Ngokusho imiyalelo, umuthi kufanele ibekwe endaweni emnyama, lapho bangaveziwe ukuqondisa elangeni. Ngakho izinga lokushisa isitoreji kumele singeqi 25 degrees Celsius. Futhi, izidakamizwa is hhayi Kunconywa ukuba ibekwe lapho ungathola nabantwana abancane.

Impilo eshalofini of isidakamizwa "Glutoxim" sekuyiminyaka emithathu. Ukusetshenziswa kwezidakamizwa ekupheleni kwalesi sikhathi, akuvunyelwe nhlobo.