"Lantsid": yokusetshenziswa, incazelo izidakamizwa, analogue, ukubuyekezwa

Izilonda we wokugaya ukudla ipheshana isifo kungenzeka ngokuzumayo. Ukuze ekwelapheni lesi sifo ngokushesha kufanele ubuze gastroenterologist abanolwazi.

Ngemva Ukuhlolisisa udokotela kumele linqume elwa ne-isilonda. Indlela ephumelela kakhulu lezi izidakamizwa "Lantsid". Intengo yaleli izidakamizwa uzobe ezibalwe ngezansi. Ngaphezu kwalokho, uyofunda ukuthi izakhiwo e esingokwemvelo wathi izindlela, uma kwadingeka iyiphi analogue nendlela ukuthatha kahle.

Ukwakheka, incazelo, emabhokisini kanye nokusungulwa

Ukulungiselela "Lantsid" ikhishwa ngesimo gelatin amaphilisi (kanzima). Banezinhliziyo umbala oluluhlaza kanye nokuqukethwe ngesimo granules emhlophe.

Isithako asebenzayo kule umuthi lansoprazole. Futhi amaphilisi ukusekelwa zici ezilandelayo: mannitol, povidone, monohydrate lactose, cetyl utshwala, sucrose kanye phthalate hypromellose.

imithi Okubukwe okuthengiswa ibhamuza amaphakethe kanye amabhokisi.

umphumela we izidakamizwa

Uyini izidakamizwa "Lantsid"? Yokusetshenziswa Lithi kuyinto inhibitor ezithile H ⁺ K ⁺ -ATPase (proton futha). umzimba wayo wenziwa amaseli (parietal) isisu. Kuleli fomu esebenzayo sulfonamide nemikhiqizo.

Lokhu kuvimbela izidakamizwa lo uketshezi of hydrochloric acid, nokuncipha basal kwavusa uketshezi.

Nge lipophilicity okusezingeni eliphezulu, kusho kunalokho kalula lingena amaseli esiswini (parietal), bese, sokugxila kubo siba nomphumela cytoprotective, okwandisa uketshezi of Bicarbonate nokukhuphula oxygenation esikhulu isitho wokugaya ukudla mucosa.

Izinga kanye izinga okusithiyayo of basal kwavusa uketshezi of hydrochloric acid kukhona umthamo nasekuthengeni. pH Its lenyuka emva 1-2 amahora amahora 2-3 emva ukungenisa 15 mg izidakamizwa futhi 30 ngokulandelana.

Lo muthi akunamthelela le motility pheshana emathunjini. Umthelela inhibitory zomuthi kuboniswa ezinsukwini zokuqala ezine reception. Ngemva kokuphothulwa ukwelashwa amahora 40 asidi uhlala okungenani 50% izinga basal.

Ukuhoxiswa ukulungiselela okunjalo akukhona ejwayelekile.

izakhiwo zomuthi

Ukulungiselela "Lantsid" (tablet) amafomu esiswini mucosa Iga ethize Helicobacter pylori ngu ezivimbela ukukhula H. pylori nokukhuphula umsebenzi neminye imithi.

Futhi kusho ithiya ukukhiqizwa kwe pepsin futhi pepsinogen kwandisa lokuhlushwa igazi.

I kinetics zomuthi

Kungakhathaliseki imithi ugxile "Lantsid"? Yokusetshenziswa uthi lokhu ukumuncwa kusho siqala ngokushesha ngemva ukulungiselela eshiya esiswini. Ubuningi bafinyelela inani eliphakeme labangu lansoprazole egazini waphawula ngemva kwamahora angu-1.7.

ukusetshenziswa Ukudla kunciphisa ukumuncwa futhi bioavailability zomuthi.

Ingxenye-ukuphila lansoprazole kuyinto cishe amahora amabili. Lokhu akuthinti okuyisikhathi nokucindezela uketshezi esiswini.

Isiphetho izidakamizwa kusukela umzimba Kwenziwa ne Bile kanye nomchamo.

ubufakazi

Yikuphi izifo kakhulu ngempumelelo liziphatha imithi "Lantsid"? Izibuyekezo bathi kusho kahle uphulukisa lezi zifo ezilandelayo:

• Reflux esophagitis;
• non-isilonda dyspepsia;
• isifo isilonda peptic (exacerbation) emathunjini;
• esophagitis, erosive futhi izilonda emathunjini;
• izilonda we wokugaya ukudla ipheshana ukucindezeleka;
• Ellison - Zollinger.

Izimo

Kwezinye izimo, awukwazi ukuthatha amaphilisi "Lantsid"? Iziyalezo yokusetshenziswa uthi Izimo kubhekwe izindlela isimo elandelayo lesiguli:

• ibele;
• senyanga yokuqala nokukhulelwa;
• izimila ebulalayo e ipheshana wokugaya ukudla;
• Hypersensitivity ukuze imibuso eyakha lo izidakamizwa.

Qaphela lokhu izidakamizwa ezinqunyiwe abantu yokwehluleka kwesibindi, le trimesters sokukhulelwa wesibili nowesithathu, iziguli esezikhulile kanye neziguli nge ezincane.

Nomuthi "Lantsid": yokusetshenziswa

capsule kuhlongozwe ezithathwe ngomlomo. Kufanele ezokugwinywa lonke ngaphandle ukuhlafuna.

Lapho erosive futhi esophagitis esidalwa yizilonda emathunjini sibe futhi isilonda peptic we imithi isisu enqunyiwe 30 mg nsuku zonke kwaze kwaphela amasonto 4-8. Uma wayefisa, umthamo luyanda 60 mg ngosuku.

Lapho izilonda ukucindezeleka futhi peptic isifo isilonda 12 imithi isilonda duodenal Kunconywa ukuthatha 30 mg ngelanga ngesinyathelo esisodwa. Kwenze okungcono ekuseni, kwasekuseni, amasonto 2-4.

Lesi sifo Zollinger - Ellison imithi Isikali is kushintshwe ngamunye.

Lapho esophagitis Reflux ukuthatha imithi ngenxa ngenyanga isamba 30 mg ngosuku.

Ukuqeda Helicobacter pylori izidakamizwa Kunconywa ukuba asebenzise 30 mg kabili ngelanga. Ukuze uthuthukise zokwelapha umphumela nomuthi kuhlanganiswe ngezilapha magciwane ezifana "clarithromycin" noma "amoxicillin". Ukwelashwa okufanele kuhlale okungenani ngesonto.

Ngo esidalwa yizilonda emathunjini sibe dyspepsia ukulungiselela isetshenziswa amasonto 2-4 at umthamo 15-30 mg ngosuku.

Lapho yokwehluleka kwesibindi, kanye asebekhulile kuqale ukwelapha nge-umthamo nengxenye. Base landa Kunconywa, kodwa hhayi ngaphezulu kuka-30 mg ngosuku.

side effects

Nomuthi "Lantsid Kit" kungabangela lokhu okulandelayo ohlangothini ukusabela:

• ikhanda, ukukhathazeka, ukucobeka, ukozela, isiyezi, ukucindezeleka;
• ukunciphisa noma ukunyusa ngesifiso, hyperbilirubinemia, isicanucanu, candidiasis emathunjini, ubuhlungu besisu, transaminases isibindi ephakeme, uhudo, izilonda emathunjini, ukuqunjelwa;
• ukukhwehlela, engenhla zokuphefumula ipheshana izifo, pharyngitis, umkhuhlane syndrome, rhinitis;
• ukuqubuka kwesikhumba, i-erythema multiforme, photosensitivity;
• kwegazi, thrombocytopenia;
• Alopecia, myalgia.

izidakamizwa ekuhlanganyeleni

Ukulungiselela "Lantsid Kit" siyehla ukuqedwa ejenti zazo akheka esibindini ngu microsomal namachibi (isb, njengokuthi "Phenytoin" "Diazepam" futhi anticoagulants ngokungaqondile).

Ukusetshenziswa ngesikhathi esisodwa lansoprazole siyehla ukumuncwa pH ancike izidakamizwa, okuqondene amaqembu acid ababuthakathaka. Futhi nomuthi kubhekwe ngesivinini ukumuncwa yizidakamizwa amaqembu isizinda.

"Lantsid" kuvimbela ukumuncwa "ketoconazole" yensimbi nosawoti "Ampicillin" futhi "Digoxin".

Lansoprazole ngo-10% kunciphisa imvume "theophylline".

Sucralfate kunciphisa bioavailability of lansoprazole ka 30%. Kule ndaba, kubalulekile ukugcina isikhawu phakathi yokwamukela izindlela wathi (imizuzu 30-40).

Lansoprazole iyahambisana "Indomethacin", "i-ibuprofen", "diazepam", "warfarin", "Propranolol" izinto zokuvimbela inzalo temlomo, kanye "prednisone" futhi "Phenytoin".

Antacids kufanele sinikezwe imizuzu 60 ngaphambi noma 2 amahora ngemva isimiso sokuqondisa 'Lantsida "ngoba kakhulu ukubambezela futhi sinciphise ukumuncwa lakamuva.

izincomo ezithile

Ngaphambi nangemva ukwelashwa nge "Lantsid" kudingeka ukulawula endoscopic kwesimiso lesiguli. Lokhu kuyadingeka ukuze siqambe ukuthuthukiswa umdlavuza, njengoba ukwelashwa kungase kufihle izimpawu zesifo kanye alibale uphethwe yini.

Inani kanye analogue

Kungakanani kukhona "Lantsid" capsule? amanani abo imayelana 200 ruble. leli thuluzi Ungashintshanisa nezinye izidakamizwa uma kunesidingo. Ukuze wenze lokhu, ibhekisele gastroenterologist.

Analogue zomuthi okuxoxwa ngayo i- "Akrilanz", "Lansoprazole", "Gelikor", "Lanzaptor", "Lanzap", "Lanzabel", "Loenzar-Sanovel", "Lansofed", "esingumGreki".

Izibuyekezo

Iziguli eziningi aphendule "Lantsid" izidakamizwa (analogs zomuthi banikezwe ngenhla) kuphela ohlangothini oluhle. Abathengi ukusho ukuthi emva kwezinsuku ezimbalwa ukwelashwa izimpawu abuhlungu peptic isilonda isifo ngokushesha zinyamalale. Ngaphezu kwalokho, lihambisana namanye nemithi ithuluzi ikhuthaza okusheshayo ukuphulukiswa erosions futhi ulceration phezu mucosa emathunjini.

I yokuntula lokhu imithi zihlanganisa inani elikhulu ukusabela ezingezinhle. Nakuba ngokuqondene zonke izidingo nodokotela ngokubukeka kwabo kungagwenywa.