APTT ephakanyiswe: okwenzeka kungani lokhu? Khulisa APTT ngesikhathi sokukhulelwa

APTT (isebenze thromboplastin ngokwengxenye isikhathi) - lena kuyinkomba ebaluleke kakhulu igazi ekunqandeni, okuyinto ikuvumela ukuba kutholakale ingozi amahlule noma okuvela ukopha. Kahle ekuhloleni umsebenzi ohlelweni coagulation, ungakwazi ukunquma indlela okunzima lesi sifo, futhi ukhethe ukuphathwa ngendlela efanele. Ake sixoxe ngakho.

kuyinto isivivinyo APTT kanjani?

Kuhlatiya ku ngesilinganiso igazi ekunqandeni kuyabaveza kwezinso systemic ngokuvamile ibonisa ukuthi kukhona ukwephulwa ambalwa kanye izinkomba qualitative ka igazi.

azihlole wenziwa iphethini ethize. Okokuqala, indaba ifanele ihlolwe, okumele kunezelwa tube eliqukethe anticoagulant yokubopha calcium ion, ngenxa lapho igazi kungaqali ihlule. Zilandelwa ngu centrifugation ukuhlukanisa plasma kusukela zegazi nezinye izakhi. Ngemva kwalokho, isivivinyo tube ingezwe phospholipids, calcium chloride futhi Activator. Kusukela ukuhlola isikhathi kwakhiwa lapho ihlule legazi is.

Phospholipids kusebenze indlela extrinsic of coagulation, ne-calcium chloride kuyinto nemiyo ebalulekile inqubo coagulation. uhlaziyo okunjalo ngeke ukuhlola ngokugcwele inqubo thrombus ekwakhekeni, kodwa kuyabaveza kwezinso in the rate, ukuze ke ubheka izimbangela zalesi simo.

Ngezinye izikhathi kuvela ukuthi APTT anda noma kwehle. Lokhu kukhomba izinkinga ezikhona emzimbeni.

kuyinsakavukela

Inkomba kukalwa ngemizuzwana kanye kungahluka ngenxa amandla, ubudala isiguli kanye nokwelashwa. APTT Jwayelekile omdala womuntu ivela imizuzwana 28 kuya ku-40. Ngo izinsana, lesi sibalo ephakeme 1-3 imizuzwana.

Isigqugquzeli igazi aPTT sitholakale lapho noma iyiphi isici ekunqandeni kuyehla noma landa ngamaphesenti angaphezu kuka-30%. sehliselwe ngokuvamile ibonisa hypercoagulability.

Ukunqunywa APTT e abadala nezingane ligcinwe ukuze kutholakale imbangela yokushona abampofu amahlule, kanye nokuhlola ukusebenza ukwelashwa nge anticoagulants.

Izizathu okwandisa APTT

Abaningi kakhulu ecasukile uma they thola cishile ukuthi APTT anda. Kusho ukuthini? Lokhu kwenzeka uma kukhona ingozi ebangela ukopha. Izizathu kungaba:

1. Inani ezinganele vitamin K emzimbeni. Lokhu kukhomba izinkinga wokugaya ukudla, ngoba lokhu Vitamin ikhuthaza synthesis amagciwane emathunjini. Iphinde kubalulekile ukusebenza evamile zonke izakhi ezijiyisayo. ukuntula kwalo kwenzeka ngenxa dysbiosis, nge yokudla nolaka, okungaholela ekwelashweni eside ngemithi elwa namagciwane.
2. kwezinso bofuzo okuhlotshaniswa ukuhlukumeza nemingcele qualitative ambalwa kwegazi. Kulokhu, Inkomba APTT zanda kakhulu.
3. Kwangemva Kokubeletha ukopha, wegazi acute, DIC.
4. Hemophilia uhlobo A, B, C.
5. Ukuba khona masosha omzimba egazini ngokumelene izici ukusonga futhi lupus anticoagulant.
6. ukulungiselela okungafanele ukuhlaziywa, le ingress kwephutha heparin e isampuli.

Ukwandiswa APTT, ingane ingase futhi kube ngenxa yalezi zizathu.

APTT ngesikhathi sokukhulelwa

Phakathi nenkathi yokukhulelwa, le isebenze ngokwengxenye thromboplastin isikhathi isiqala ukushintsha. Uma Izinga umuntu ovamile phakathi imizuzwana 28 kuya ku-40, kwabesifazane abakhulelwe kuba imizuzwana 17-20. Lokhu kusho ukuthi kuyehla. Izinguquko ezinjalo, ngakho avuse lezi zinto ezilandelayo:

• Kulesi sikhathi esinzima e emzimbeni womuntu wesifazane, i utero-esinomhlapho kwegazi ezengeziwe. Placenta siqukethe sebuningini izitsha. Ngisho uma isifika ihlukane encane, ukulahlekelwa igazi kungaba ephawulekayo. Ngokuvamile lamabutho kwenzeka ngenxa lenyuka lesizalo ithoni.
• Phakathi lokuzalwa ngokuvamile owesifazane ndawo ilahlekelwa 400 ml igazi. Lokhu kwenzeka ngokushesha kakhulu, futhi uhlelo coagulation kufanele silungele nokulahlekelwa okunjalo okunzima igazi, ngakho amahlule nazo isiqala zimiswe masinyane ukuze uvimbele ezinye ukopha.

Kungani APTT kwaphakanyiswa sokukhulelwa?

APTT luyanda uma isikhathi ekunqandeni kuyinto ngemizuzwana engaphezu kwengu-40. Lokhu kunciphisa ikhono amahlule ukwakha, kuphumele ingozi ephezulu ukopha.

Ngokuvamile APTT anda uma owesifazane okhulelwe is ukuphuza imithi elwa namagciwane, heparin, aspirin ne izidakamizwa thrombolytic. Ngaphambi kumelwe bavivinywe, kufanele azise udokotela yabo.

Ukwanda APTT kubonisa ukwehla ikhono igazi ukuze ihlule, futhi kwenzeka izimo zokucabanga okubangelwa isifo ezilandelayo:

• isifo sesibindi egqoke waveza ukwehluleka hepatic, kuhlanganise futhi ziphathwe yisifo sokuqina. Kulokhu kukhona kungukuphula synthesis izakhi ezijiyisayo egazini.
• Ukungabi vitamin K, kwenzeka ngokumelene isizinda dysbiosis esiswini, kanye ngenxa yokudla engafanele.
• Umdlavuza wegazi.
• Hemophilia uhlobo A, B, C. Lena esiwufuzo elinesimo ukuntula azalwa naso we izakhi ezijiyisayo, okuvame ukuphumela ukopha nokuguqulwa zenzeka.
• isifo Von Willebrand sika.

isiphetho

Ukuhlaziya APTT ngempela eyenziwa ngaphambi ukusebenza kungafiki ukuthola fast kanjani negazi akunakulidla ihlule. Ukwenyuka noma ukwehla kusukela kuyinsakavukela likhombisa pathologies ezehlukene. Ukuze ugweme ingozi ukopha, aphathe ngokufanele.