"Avodart": imfundo amazwana. "Avodart" (amaphilisi): Inani

Yini oyaziyo izidakamizwa "Avodart"? Analogs, intengo izinkomba kanye nemiyalelo ye ithuluzi izokwethulwa kulesi sihloko. Uyofunda ukuthi izakhiwo esivela ku izidakamizwa wathi eqenjini eyenza imithi eyilunga lokho likhona ngezithako zawo, njalo njalo. D.

Ubujamo, incazelo, emabhokisini kanye nokusungulwa

Umuthi "Avodart" iza ngendlela ethambile gelatin amaphilisi, oblong futhi opaque ophuzi, esibhalwe ukuthi "lo GX CE2" ikhodi. On ukudayiswa lo muthi ingatholakala amakhadibhodi amabhokisi, okuyinto ezibekwe ne amashashaza amaphilisi 90 noma ezingu-30.

Isici esebenzayo olucutshungulwayo kusho izenzo dutasteride, futhi asetshenziselwa izingxenye njengoba ozikhethela: gelatin, butylhydroxytoluene, triglyceride, ama-titanium dioxide, Uyinki obomvu sokuphrinta, mono- acid, caprylic acid, glycerin, lecithin, nensimbi oxide abamnyama.

izici pharmacodynamic

Ngisiphi isiqhema iyona ikhambi elenziwa "Avodart"? Iziyalezo yokusetshenziswa Lithi kuyinto ejenti anti-androgenic. umenzeli asebenzayo kuyinto inhibitor ombaxambili enzyme 5-alpha-reductase. Le ngxenye uyakwazi zivimbela izinqubo ukuguqulwa kwe-testosterone ukuze DHT. Lokhu kwenzeka ngenxa nokucindezela umsebenzi 5-alpha-reductase lwezinhlobo lokuqala nelesibili.

Emva kokuthola "Avodart" ukuchama evamile, kunciphise Usayizi endlaleni engasesinyeni, futhi kwandisa amathuba ikhambi isifo ngaphandle ukuhlinzwa.

Izici izidakamizwa

Ngokwe-art, "Avodart" amaphilisi abonise nethonya zokwelapha emva kwezinsuku 8-15 emva kokuqala ukwelashwa. Umthamo ephakeme zomuthi, kulapho-ke kuthinta nokukhiqizwa kwamangqamuzana DHT.

izakhiwo pharmacokinetic

I nomuthi "Avodart", intengo oboniswe ngezansi, kutholakala igazi lokuhlushwa esiphezulu emva 1.5 ihora ngemva ukungenisa. bioavailability Its 60%. ukudla ngesikhathi esisodwa eyanele akunamthelela le kinetic imingcele imithi.

Kulesi kusho degree kahle esikhulu uxhumano plasma amaprotheni (cishe 99%). Kufanele kuphawulwe ukuthi ekuphathweni ngendlela ehlelekile nokuya njalo-12% isithako esebenzayo ingena isidoda.

Njengoba isiphelo sesimiso izimali? Abakushoyo ngalokhu umhlahlandlela impendulo? "Avodart" lisasetshenziswa akheka kubantu. Cishe 2-15% we ketshezi esebenzayo excreted ingashintshiwe ngokusebenzisa esiswini. ukuqedwa Qedela zomuthi Kwenziwa cishe inyanga ngemuva kokuphela yokwelapha.

Ochwepheshe bathi ngisho nangemva kwezinyanga eziyisithupha esincane zomuthi kungatholakala egazini.

ubufakazi

babhekwa izidakamizwa singasetshenziswa eyabelwe ngayiphi injongo? Nquma ukuthi lo myalo futhi impendulo? "Avodart" - umuthi isetshenziswa kulezi zimo ezilandelayo:

• monotherapy nokuvinjelwa ukuqhubeka wendlala wendlala Hyperplasia (amafomu ingozi) ngokunciphisa lingakanani, ekuthuthukiseni ukuchama, izimpawu, kanye ekunciphiseni amathuba kokungenela kuhlinzwa, ingozi acute nokugcinwa urinary;
• therapy inhlanganisela ngokuhlanganyela alpha1-adrenergic, lokuvimbela ukuqhubeka wendlala indlala Hyperplasia (amafomu ingozi) ngokunciphisa lingakanani, ekuthuthukiseni ukuchama, ukuthanjiswa izimpawu, ekunciphiseni amathuba kokungenela kuhlinzwa, ingozi acute nokugcinwa urinary.

Izimo

Ungasebenzisi izidakamizwa "Avodart" ku:

• hypersensitivity kuya dutasteride, kanye nezinye izinto izidakamizwa;
• hypersensitivity kuya inhibitor 5-alpha-reductase.

Kufanele kuqashelwe ukuthi le izidakamizwa is contraindicated ukwamukela izingane kanye ocansini bubuhle.

Qaphela "Avodart" kufanele ezinqunyiwe esingamahlalakhona hepatic.

Amaphilisi Abonayo "Avodart": yokusetshenziswa

Imithi ezithathwe ngomlomo, kungakhathaliseki ukudla.

Capsule kugwinyiwe lonke ngaphandle ukuhlafuna noma ukuvulwa (okuqukethwe kungase kubangele ubuhlungu we oropharynx).

BPH abadala namadoda amadala izidakamizwa iqondiswa i inani 1 capsule kanye ngosuku.

Naphezu kweqiniso lokuthi umphumela zokwelapha zalesi imithi iza amasonto amabili, kutuswa ukuthatha okungenani ezinyangeni eziyisithupha.

Ukuze ekwelapheni wathi isifo "Avodart" lingase lisetshenziswe futhi monotherapy noma inhlanganisela ene-alpha 1-blocker.

A imithi ekhethekile reception

Ngezinye umthamo micrograms 500 ngosuku, ikhishwe ngokusebenzisa izinso cishe 0.1% ekwakhiweni. Kule ndaba, asikho isidingo ukunciphisa umthamo abantu ngomsebenzi kahle kohlelo urinary.

Iziguli imithi "Avodart" isibindi enezinkinga okufanele zithathwe ngokucophelela okukhulu, njengoba isithako yayo asebenzayo asitholayo umzimba olunzulu emzimbeni.

side effects

Yiziphi imiphumela emibi zenzeka ngenkathi ethatha ngaphansi ukucatshangelwa imali? Yini abantu bathini mayelana Izibuyekezo wezokwelapha? "Avodart" kungabangela ukusabela elandelayo enqabayo:

• abantu abaningi abasinaki futhi nokucindezeleka;
• silume ukuqubuka kwesikhumba, isifuba edema, nokungezwani komzimba nezinto (kufika ku angioedema);
• iqothukile phezu umzimba futhi hypertrichosis;
• ubuhlungu wamasende nokuvuvukala;
• ukwehla libido bese beshayela ngokobulili, Erectile Dysfunction, ubuhlungu nokuvuvuka amabele, izinkinga ababa nazo ejaculation.

Amathuba okuvela ohlangothini ukusabela ancipha kakhulu nge okwandisa isikhathi yokwelapha (isb, owesibili amaphilisi eyamukelayo).

Uma sihlanganise "Avodart" nezinye imithi, tigameko nezinhlobo izigigaba ezingezinhle kungahluka kancane.

izincomo ezithile

Amaphilisi Abonayo "Avodart" ayikwazi lwembula, kanye nokuqukethwe zabo Gwema ukuthintana nolwelwesi lwamafinyila kanye isikhumba. Uma izidakamizwa namanje uthola esikhunjeni, kufanele kube ngokushesha uxubha ngamanzi agobhozayo.

Inhlanganisela dutasteride futhi ukuhlola kwe-alpha-blocker kwandisa ingozi yesifo senhliziyo.

Ngaphambi kokuthola izidakamizwa, kanye therapy kubalulekile ukuba afeze Ukutadisha endlaleni engasesinyeni (rectal digital, assays ngoba PSA futhi t. D.).

Izindleko amaphilisi kanye amalungiselelo efanayo

Kungakanani buyisidakamizwa "Avodart"? Intengo yaleli izidakamizwa kuphezulu kakhulu. Thenga amaphilisi 30 zomuthi unga ruble 1500-1600.

Okuvame kakhulu "Avodart" analogue zingamathuluzi ezifana "Proscar", "Adenosterid", "Finpros", "Urofin", "prostane", "Penester", "Finistère".

Asinakusho ukuthi izindleko lezi izidakamizwa kungenzeka kancane kunakunoma kubhekwe yithi amaphilisi.

Izibuyekezo

"Avodart" - umuthi omuhle esithandwayo esisetshenziselwa ukwelapha kanye nokuvinjelwa BPH. Uphenyo kungaba ukuhlangabezana ezahlukene kakhulu. Ezinye iziguli ukubika ukuthi emva kwezinyanga ezingu-12 isebenzisa i-izidakamizwa kakhulu kwehle indlala wendlala. Nokho, ngezinye ekunqanyulweni yokwelapha, anda futhi. Ezinye iziguli unganelisekile kakhulu nge izindleko eziphakeme izidakamizwa, kanye nezinkinga Erectile futhi kwehle isifiso sobulili ngemuva yokwemukela yakhe.

Ochwepheshe bathi ukusabela komzimba okufana zinyamalale bebodwa emva 3-4 nezinyanga zokwelashwa.