"Dobutamine": yokusetshenziswa, ifomu ukukhululwa, umthamo, ukubuyekezwa, analogue

Izinkinga nemithambo yegazi kanye inhliziyo ijwayeleke kakhulu kubantu abadala. Kodwa ngokuvamile kuphakama izifo ezifana neziguli esemancane. Ukuze uthuthukise ngezimo zesiguli, odokotela bavame linqume izindawo inhliziyo. Omunye wabo lesi sidakamizwa "Dobutamine". Yokusetshenziswa, ifomu ukukhululwa, analogs nezakhiwo izidakamizwa wathi ethulwa ngezansi.

Ukwakheka, emabhokisini ifomu izidakamizwa

I nomuthi "Dobutamine", yokusetshenziswa okuyinto eziqukethwe isixha iphepha obukhulu, iqukethe into njengoba dobutamine hydrochloride, nezingxenye ezihlukahlukene ukwesekwa.

Ngo ukudayiswa izidakamizwa iza ngendlela kungekho nto enemibala emihle noma kancane aphuzi isixazululo esobala for ukumnika, ukuthi ibekwe ingilazi izitsha eziyisikhombisa.

Futhi, lo muthi angathengwa ngesimo umkhiqizo nqabela-omisiwe futhi sigxile isixazululo.

I izakhiwo pharmacodynamic i isixazululo komjovo

Uyini izidakamizwa "Dobutamine"? Yokusetshenziswa (ampoules lo muthi angathengwa ngasiphi ikhemisi) Lithi kuyinto cardiotonic, a catecholamine zokwenziwa ne-beta-1-agonists.

Lo muthi unamandla ukuze sikhuthaze receptor beta-1-adrenergic we myocardium, ukhulise contractility yayo. It kwandisa ngomzuzu, futhi umthamo ngomvimbo izitsha inhliziyo negazi kunciphisa OPS.

Ngemuva kwesicelo yaleli izidakamizwa kubange ukwanda alinganiselayo kwenhliziyo. umphumela Chronotropic zomuthi, kanye nomphumela walo omuhle dromotropic kubonakaliswa imithamo ephezudlwana.

Ngemithamo ngokulinganisela, lokhu izidakamizwa asivumelani kancane kuthinta blood pressure. Ngenxa yokuthi ukuthi unesikhathi sifushane kwesigamu-ukuphila, kufanele iqondiswa ngokuqhubekayo. Kodwa kufanele kukhunjulwe ukuthi ukwelashwa okuqhubekayo nale izidakamizwa amahora 72 noma enomthelela ngaphezulu imilutha.

Sebenzisa nomuthi "Dobutamine", yokusetshenziswa elichazwa ngezansi, kubalulekile ukulawula electrocardiogram kanyekanye, inhliziyo nomfutho wegazi lazo wawungcono.

nemingcele Kinetic we nomuthi

Umuthi 'Dobutamine "kuyokwenzeka kufanele balinde isikhathi esingakanani? Yokusetshenziswa (amaphilisi - lezo zinhlobo imithi ungakakwenzi) ubika ukuthi ngemva ukumnika emthanjeni ngomphumela izidakamizwa siyenzeka emva kwemizuzu 2. inhlanganiso yakhe esitebeleni ngisho nangemva ¼ ihora litholakala ku-plasma.

Impilo kwesigamu umuthi imizuzu 2-5.

Izinkomba ukusetshenziswa yesixazululo

Bewazi yini ukuthi kwezinye izimo, ayabelwe izidakamizwa "Dobutamine"? Yokusetshenziswa ngokuvumelana izinkomba ezilandelayo:

• ukwehluleka oyingozi inhliziyo;
• edema yamaphaphu;
• CHF decompensation (njengendlela yesikhashana ukwesekwa izindlela);
• kwehle okukhipha inhliziyo;
• kokuqhuba ukucindezeleka echocardiography (ngoba uphethwe).

Izimo ukusetshenziswa kwezidakamizwa

Ngaphansi kwaziphi izimo musa linqume ejenti inhliziyo, njengoba "Dobutamine"? Yokusetshenziswa (izidakamizwa analogue ezibalwe ngezansi) ibika ukuthi Izimo ezilandelayo:

• isimiso mechanical noma outflow wegazi ukugcwaliswa we ventricles inhliziyo (isib zenhliziyo obstructive, stenosis yomthambo i-aorta, uzwakalise tamponade inhliziyo) ;
• giperuvstvitelnost ukuze isakhi esiyinhloko;
• hypovolemia;
• Mao inhibitor.

Izidakamizwa "Dobutamine": yokusetshenziswa

Ngo izinsana, lo muthi isetshenziselwa izinkomba ekhethekile. Kuyefana nasendleleni izingane ubudala ezincane.

Kanye analogs lokhu izidakamizwa, "Dobutamine" senzelwe abaphathi emthanjeni. Ngakho ngaphambili buhlanjululwe solution, Ringer, 5% glucose noma i-sodium chloride.

Ready izidakamizwa esitolo hhayi ningi than suku. Ijubane nobude ekuphathweni incike nemingcele hemodynamic. Kule ndaba ngoba isimo lesiguli kudinga ukuqapha njalo. Kuyadingeka ukuqapha kwenhliziyo, umfutho wegazi value, futhi okukhipha inhliziyo (uma kungenzeka).

Ngakho kulokho Isikali ezinqunyiwe "Dobutamine hexane?" Yokusetshenziswa libike ukuthi omdala abantu iqondiswa i inani 2.5-10 mg / kg / iminithi (ezimweni ezingajwayelekile -. 40 UG / kg / iminithi). Ngokuqondene nabantwana, bona izidakamizwa yaphathwa umthamo 1-15 mcg / kg / imiz.

Imiphumela emibi ngesikhatsi ukwelashwa nge izidakamizwa

Yini abantu basabele ngendlela embi angabangela izidakamizwa "Dobutamine"? Yokusetshenziswa ukhuluma ngani okuvela okungenzeka miphumela elandelayo:

• ukulunywa, pectoris angina;
• bronchospasm;
• ukuqubuka, palpitations;
• tachycardia, Ukugodola;
• phlebitis kusayithi umjovo;
• arrhythmias inhliziyo (ventricular fibrillation arrythmia);
• anda systolic blood pressure;
• isicanucanu, nekhanda.

Zonke ukusabela nge izitsha inhliziyo negazi iyashiyana umthamo zomuthi. Ayevame iyanyamalala ngemuva ukumisa we ukumnika, noma nge ukwehla ijubane layo uma igijima.

Inani kanye efanayo nemithi

Yeka ukuthi kuyinto "Dobutamine hexane?" Yokusetshenziswa akukuniki impendulo yalo mbuzo. Pharmacy, intengo yaleli izidakamizwa kungenzeka ruble mayelana 350-450.

Into okufanele ibhekwe ukuba esikhundleni imithi? kumakhophi are izidakamizwa ezilandelayo: "Dobuzhekt", "Dobutamine Solvay", "Dobutamine Giulini", "Korotrop", "Dobutamine Lachema", "Dobutamine Nycomed".

Izibuyekezo Ochwepheshe Imithi

Umthengi Izibuyekezo ekulungisweni kubhekwe akukho. Lokhu kungenxa yokuthi enjalo ejenti cardiotonic esetshenziswa kuphela ezimweni eziphuthumayo (isib ukwehluleka oyingozi inhliziyo, uma ukuwa Inkomba zenhliziyo encishisiwe kwesokunxele ventricular umsebenzi contractile). Ngokuvamile, lesi sifo ebonwe cardiomyopathies, ukushaqeka ukonakala, isilethikusebenza, bese uvula ukuhlinzwa kwenhliziyo.

Ochwepheshe bezifo, imithi ibhekwa isisekelo ukuphathwa kwemithi ukushaqeka cardiogenic. It is hhayi esetshenziselwa ukwelapha ezingamahlalakhona yokumelwa yinhliziyo.

Ngenxa yokuthi lokhu imithi kungabangela arrhythmia futhi tachycardia, kufanele kusetshenziswe kungakapheli isikhathi esifushane kuphela ezimweni ezimbi kakhulu, okungukuthi ku-acute yokumelwa yinhliziyo.

Akunakwenzeka ukuba uqaphele iqiniso lokuthi lokhu izidakamizwa ezahlukene elincane phakathi imiphumela ezinobuthi kanye Ukweqiwa zokwelapha.

Ngokungafani izidakamizwa "Dopamine" Akazange kubangela vasodilatation.