I amaprotheni ku umchamo. kungenzeka ahlukahlukene Izizathu

Isilinganiso ngoba aqukethe amaprotheni amaningi e umchamo - kuba phambi serum amaprotheni ingxenyenamba, okuyinto elicwengekileyo ngokusebenzisa izindonga capillary ku izinso. Ngokuvamile, izinga kumele singeqi 0,002 g / l, uma ukuqasha ukuhlaziywa njalo ekuseni. Emini, 50-150 mg amaprotheni ku umchamo - kuyinto evamile. Kodwa phansi kwalo futhi amaprotheni esiphakeme umchamo, izizathu ngeziphambeko ezinjalo kufanele uhlolisisa emtholampilo, ikakhulukazi uma amaprotheni liphakeme kwabesifazane abakhulelwe.

Mshini yenqubo, lapho ukwanda inani amaprotheni, ama-ngocansi izinso engaphansi ulwelwesi, kunalokho xaka. It iqhaza hyaluronidase. Lokhu-enzyme, ngaphezu kweminye imisebenzi, ahlahlele mucopolysaccharides e serum. Ukwandisa umsebenzi wayo sithuthukisa permeability ka capillary izindonga ulwelwesi permeability, nezoqala kudlule i-molecule ye-protein.

Lapho iprotheni e umchamo, izimbangela kungaba yiqiniso (izinso) neyamanga (extrarenal). Iqiniso noma falsity lesi sifo, ukubandakanya yayo inqubo yesikhashana noma okungamahlalakhona kungakwenza isethwe kuphela odokotela.

Kungani amaprotheni ku umchamo

Isisekelo Kuhlanganisa amaprotheni emzimbeni womuntu - kungcono ukwaziswa kwezakhi zofuzo. It likhona sofuzo kubantu ifomu bebhala ngendlela eyimfihlo. Complicated ezokuthutha uchungechunge, zamagama, futhi edluliselwe thize kilelihlelo kuholela ukuba khona futhi efanele ukusebenza amaprotheni emzimbeni. Bika omunye izigaba neketanga eyinkimbinkimbi kugucuka ezilandelanayo amaprotheni zibe amandla elawula futhi bahlele umsebenzi wabo, futhi aholela kumiphi ivela amaprotheni umchamo.

Izizathu komgomo ezinjalo akunakubangelwa izici transiently noma stably okubangelwa ukuphazamiseka umsebenzi emzimbeni. Akunakwenzeka ukunikeza impendulo oluphelele yombuzo kungani amaprotheni ku umchamo, ngaphandle nokwenza izinhlolombono esibanzi.

Khulisa amazinga amaprotheni kungase kube nomthelela kule nkinga yokungadli kahle kwegazi kwezinso:

• anomalies ekuthuthukiseni vein kwezinso;
• izinguquko ngenxa imiphumela anobuthi ezindongeni capillary ku izinso;
• ukushintsha ngaphansi kwethonya izidakamizwa (ukwamukelwa ukuphuza noma ukuzibhala);
• ukwephulwa emisebenzini ye tubules we nezinso;
• izifo zenani elikhulu eziyifa kanye azalwa nako.

Uma isikhathi eside kukhona amaprotheni ku umchamo, izizathu kungase kube izifo ezihlukahlukene zomzimba ezifana wokugaya ukudla isifo uhlelo, igazi kakhulu, imiphumela ukusha, ukulimala, zizwa amakhaza, ukuzikhandla ngokomzimba noma isipiliyoni ngemuva imizwelo enamandla. Kulokhu, lesi sifo singumbulali ifomu zesikhashana, kanye nokuqedwa izizathu kokushiya amaprotheni kusukela umchamo.

Permanent (noma eside) khona amaprotheni ku umchamo (proteinuria) elikushoyo isifo sezinso futhi uma ezinye izimpawu ungekho.

izinto ezingabangela amaprotheni ku umchamo

• glomerulonephritis isifo;
• glomerulosclerosis ngenxa sikashukela;
• e kwezinso thrombosis semithambo;
• khona izinso congestive;
• ezinso kanye nezinye izifo.

Ukuxilongwa kanye nokwelashwa

amaprotheni ku umchamo kubhekwa inkambiso okuqukethwe zayo ezingaphezu kuka-50 - 150 mg / usuku. Inani sisheshe wamaprotheni kulula. Ngokuvamile, lokhu ukutholwa uchama. Emini ke uya Pee ku inqubo ethile. Uhlaziyo liphindwe ugweme isici okungahleliwe ukuthi ungakwazi ukushintsha isibonelo Imiphumela eziqoqiwe.

Ukuze ugweme ingozi ngesikhathi Ukuhlolwa kwesikhathi, ubuke nokuhlanzeka kwezinto zokusebenza kanye nezinto begeza le ngemomozi yakho. Ngaphezu ekuhlolweni umchamo kungenzeka iqhutshwe electron microscopy we nezinso, esiza uhlole ukwephula ulwelwesi engaphansi, ukwanda isibalo yayo ikhule ezimbotsheni kanye nosayizi yabo.

Ikakhulukazi eduze ukubukela ezingeni wamaprotheni umchamo abesifazane abakhulelwe, ngoba umsebenzi kwezinso nzima kwesibeletho likhula futhi ukwandisa umthwalo wonke umzimba futhi izinso ngokukhethekile. Norm encishisiwe futhi akufanele kube ngaphezu kwamaminithi 0.14 g / l (Assay ingenalutho).

Ukwelashwa yesifo eziyinkimbinkimbi elihlobene ne kahle umsebenzi kwezinso (noma ezinye izimo isifo ngomshini odokotela) kungaba kwenziwe kuphela emtholampilo.