"Nalbuphine": imfundo, incazelo, ukwakheka, ukubuyekezwa

Kumzwisa ubuhlungu ... Kubuhlungu ... Akukho omunye umuntu ngeke leli zwi. Lapho sinokuthile kubuhlungu, zonke ezinye izinkinga ziba ubala. Into ebaluleke kakhulu futhi okubaluleke okwamanje - ukwenza ukungakhululeki wanyamalala.

Modern Ikhemisi ilungele ukunikela amakhasimende ayo yokusungula omkhulu izidakamizwa izinzwa nezimiso ezahlukene isinyathelo. Omunye imithi enjalo kuyinto "nalbuphine." Ukufundiswa ulawula njengethuba agonist futhi-opioid yokwamukela omelene, a analgesic kwezidakamizwa, afakwe ohlwini ohlwini lwesithathu izidakamizwa kwezidakamizwa.

Ukwakheka kanye pharmacodynamics

The main esebenzayo isithako "Nalbuphine" kuyinto nalbuphine hydrochloride. Umuthi kuyinto iqembu analgesic opioid (izidakamizwa ezinikeza ithonya nomzimba womuntu, efana isenzo opium). Umgomo we isinyathelo zomuthi "nalbuphine" imfundo on isicelo uthi lokhu okulandelayo: isithako esebenzayo eyinhloko kuvimbela ukudluliselwa ubuhlungu amaza phakathi izinzwa isimiso sezinzwa. Umuthi kuvusa izingxenye ephakeme zobuchopho, kanjalo ekushintsheni umbono ngokomzwelo ubuhlungu.

Effect "Nalbuphine" emzimbeni womuntu ifaniswe ne umphumela "Morphine". hydrochloride Nalbuphine kuvusa isikhungo ukuhlanza, uyakwazi ukucindezela ikhaliphe moya, kunomphumela sine. Imithi suppresses isikhungo zokuphefumula, kodwa ngezinga ezincane kakhulu 'Morphine "," Promedol "noma" Fentanyl ".

Khipha ifomu umthamo lwemithi

Abakhiqizi zinikeza amakhasimende abo umuthi izitsha eziyisikhombisa "nalbuphine 10" futhi "20 nalbuphine." ampoule ngalinye - 1 ml nomuthi. Eyokuqala ( "nalbuphine 10") phama pack of 10 izitsha eziyisikhombisa, kanti eyesibili - ukuze 5. "Nalbuphine" (isixazululo) yokusetshenziswa, bezempilo yangempela ukuncoma ukhethe uhlelo ngokuqinile ngamunye, kuye ngokuthi isisindo somzimba, nobukhali ubuhlungu elikulesi sihloko izifo.

I nomuthi kungenzeka iqondiswa ngemithambo yegazi, intramuscularly noma phansi kwesikhumba. A umthamo owodwa ngoba umuntu omdala kungase isukela 100 .mu.g ukuba 1 mg ngayinye esisindo kg. Umthamo lokuqala ingane - akuyona ezingaphezu kuka-300 g ngalinye 1 kg esisindo. Imvamisa isicelo se-nomuthi incike isithombe Imininingwane emtholampilo. Inkambo ukuphathwa akufanele kuhlale ezingaphezu kuka 3-4 izinsuku, kusukela umuthi lapho kwelashwa futhi kwezokuphatha ende ingase idle isikhathi esiningi.

Izinkomba ukusetshenziswa "Nalbuphine"

"Nalbuphine" imfundo manual incoma ngokungenisa eqinile ubuhlungu syndromes ukuthi kungenzeka ukuthi umataniswe nge isikhathi nasezinkingeni ezilandela ngemva kokuhlinzwa, ukungenelela izifo zabesifazane kuhlinzwa ekwelapheni isifo senhliziyo kanye nomdlavuza.

Futhi, imithi kabanzi lisetshenziswe endabeni prednarkoznoy premedication (pre-izidakamizwa ukulungiselela isiguli ukuba ukubulawa kwezinzwa okuvamile nokuhlinzwa). Empeleni, injongo eyinhloko le nqubo - ukunciphisa izinga lokukhathazeka Isiguli kanye nokuqiniswa isenzo izidakamizwa ngoba izinto zokubulala izinzwa. Eqinisweni, lena main endaweni kwesicelo of hydrochloride nalbuphine.

Ubani okufanele ayeke ukuthatha leso?

"Nalbuphine" imfundo, impendulo nochwepheshe iseluleko benqatshelwe ukwamukela iziguli ezine hypersensitivity okukhulu isithako esikhulu. Inadmissible ukusetshenziswa nomuthi wokwelapha iziguli zonke izinhlobo zezifo kwesibindi nezinso. Lokhu kungenxa yokuthi akheka "Nalbuphine" esibindini. Ifomu sokuqala nomuthi is excreted ku umchamo (70%) ngesimo nemikhiqizo excreted ku Bile.

Ayikho izidakamizwa iqondiswa iziguli utshwala sezidakamizwa. Ngaphandle isidingo esiphuthumayo imithi Kunconywa ukuba isetshenziswe izingane. Njengoba "nalbuphine" kunemtselela izikhungo ephakeme zobuchopho, it is hhayi Kunconywa ngesikhathi yokwelapha iziguli engazinzile ngokomzwelo (i sengqondo, ukucindezeleka nezinye. N.).

Spillover umphumela "Nalbuphine"

"Nalbuphine", ukusetshenziswa okuyinto ngenxa ithonya kwezidakamizwa emzimbeni womuntu, kungabangela imiphumela eminingi engemihle njengezindlela ezithile kusukela izinhlelo ezahlukene eziyishumi nemitshingo. Ngakho, esimiso senhliziyo nemithambo yegazi bakghone ukuphendula isicelo yentuthuko nomuthi tachycardia, arrhythmias, umfutho wegazi iyehla iyenyuka.

Kusukela isimiso sezinzwa kungadala ikhanda, okunamandla umphumela okulalisayo (ukucobeka), nesasasa. Kube zenzo ziwukubonakaliswa ngemilingo ezifana hyperactivity, ukukhathazeka anda. pheshana emathunjini kungaba uzikhumbuze ukubonakaliswa dyspepsia (ukuqunjelwa zonke izinhlobo).

Kwezinye izimo, nalbuphine imithi ' "(ngesandla siqukethe iziyalo ezikhethekile) kungabangela ezihlukahlukene komzimba nezinto (anaphylaxis kuhlanganisiwe).

Futhi, njengoba kushiwo ngaphambili, "nalbuphine" - umuthi kwezidakamizwa, ngakho kungabangela umlutha.

Ukweqiwa ngokweqile

Isikali nomuthi ngokuqinile ngayinye umthamo ngamunye nesineke kuyakhethwa kuye ngesimo jikelele, nobukhali ubuhlungu, isisindo nokunye. N. Olungasihlukanisa isicelo yayo ngaphandle udokotela kokuqondisa kungaholela overdosing. Kulokhu, njengoba umthetho, kukhona zimpawu ezilandelayo: ukucindezeleka kohlelo sezinzwa, ukucobeka, dysphoria (the antonym ka "Isasasa" kwemizwelo okugulisayo ecindezelekile, Kubonakala e ukucasuka, inzondo aphatha ngayo abanye, kalula ubudlova, njalo isimo nokuqubuka). Overdose kungaholela ukungasebenzi isikhungo zokuphefumula.

Ukwelashwa liqukethe isicelo yokuvimbela (elisho "Nalbuphine", njengoba iningi opioids - kuyinto "Naloxone"), lavage esiswini kanye therapy okunezimpawu.

mums abakhulelwe ...

Lapho ekhulelwe lokuqoka "nalbuphine" imfundo ivumela kuphela izinkomba esiqinile. Ngokuqapha okukhulu kuyinto imithi kadokotela ngenxa wazalwa kungakabi isikhathi futhi ezimweni lapho kukhona izinsolo yokungavuthwa fetus. Lezi zenzo zihlobene yokuthi "nalbuphine" ngokwanele kalula sihamba umgoqo esinomhlapho futhi zingabangela ukucindezeleka zokuphefumula ku neonate.

Futhi ngokucophelela Kunconywa imithi ngesikhathi ibele, nakuba "Nalbuphine" futhi abelwe nge ubisi lukamama ngemithamo emincane, abangenalo ukubaluleka emitholampilo (ngaphansi kuka-1% of the izidakamizwa Imininingwane iqondiswa). Noma kunjalo, asikho isidingo engozini ingane ngaphandle ngesizathu esizwakalayo.

imiyalelo Special

Isixazululo for umjovo eliqukethe e yayo Ukwakheka 10 mg / ml we hydrochloride nalbuphine ( "nalbuphine Farmeks"), manual incoma isicelo ngokucophelela in iziyaluyalu umsebenzi zokuphefumula, ngoba uyakwazi inciphise zokuphefumula ngomzuzu ivolumu ku-25%. Ngaphansi kokulawula udokotela kufanele kube iziguli ukuthatha "nalbuphine" futhi kuhambisana uremia ukuhlupheka futhi ifomu ezinzima yokungondleki, kanye nasebekhulile.

Ezigulini ezine-imithi esingamahlalakhona kwezinso noma hepatic ngokucophelela futhi ngokuqinile ngamunye alinganisiwe. Kufanele kwenzeke ukumisa okusheshayo "Nalbuphine" kulesi sigaba sama-iziguli.

Ngokuqapha kuyinto izidakamizwa kadokotela ngenxa abantu yokulimala ugebhezi, njengoba kukhona amathuba wokuthuthukisa zokuphefumula ukucindezeleka inqubo. A ofiseleka kakhulu ukuhlanganisa nokusetshenziswa "Nalbuphine" nezinye analgesics, ngenxa kuyadamba okungenzeka analgesia.

Ngaphansi kweso lwezokwelapha njalo futhi ngemithamo emincane izidakamizwa isetshenziswa isizinda narcosis, elele imithi, anxiolytics, antidepressant futhi neuroleptics. Lokhu "endaweni" kungaba avuse ukucindezeleka okweqile isimiso sezinzwa esiyinhloko futhi zokuphefumula ukucindezeleka maphakathi umsebenzi.

Okumele kuqashelwe "Nalbuphine" inikezwa yokwamukela iziguli ambulatory, okuyinto ilawulwa komgwaqo, noma labo abamagama umsebenzi ezihlobene izinga lengqondo ukusabela.

lebanga lentengo

Ububanzi intengo ebanzi ngokwanele ukuba "nalbuphine" izidakamizwa. Yokusetshenziswa, intengo izidakamizwa iwubufakazi bokuthi izidakamizwa odingeka phakathi abathengi. Ngaphezu kwalokho, analgesic umise ngokwaso njengoba i izidakamizwa ngempumelelo e abasebenzi bezempilo. Umkhiqizo iphakethe "nalbuphine 20" (5 vials) kungenzeka ukuthenga Pharmacy Russia yemali kuleli uhla ruble 620 kuya 810. "Nalbuphine 10" izobiza ruble 650 kuya 690 (pack of 10 izitsha eziyisikhombisa).

Kwezinye Pharmacy kungabonwa ukudayiswa "Nalbuphine" ku isipetu (10 mg / 1 ml), senzelwe umjovo owodwa. Izindleko lolu hlobo lokukhishwa azungeze 160 ruble.

Ukuxhumana nezinye izidakamizwa

Njengoba kushiwo ngaphambili, "Nalbuphine" (umsebenzisi iqukethe ulwazi ezifana) kanye nemithi yokunciphisa ukucindezeleka, anxiolytics, neuroleptics, hypnotics, ama-ejenti izinzwa, izidakamizwa antihistaminic nge nomphumela okulalisayo, sithuthukisa Ethanol nokudangala nomthelela isimiso sezinzwa esiyinhloko. Ukusebenzisa parallel analgesic nge-penicillin futhi phenothiazine kungabangela yokukhulisa isicanucanu nokuhlanza.

"Naloxone" (yokuvimbela) kuzonciphisa umphumela ukuchayeka opioids ngakhoke inciphise ukucindezeleka zokuphefumula nemisebenzi CNS inqubo kwabangela "Nalbuphine".

"Naltrexone" kakhulu ukusheshisa ukubonakala izimpawu sokwesulwa ku isizinda yizidakamizwa ( "e yonke inkazimulo yayo" izimpawu zingavela emva kwemizuzu 5 kuphela ngemva nokuphathwa izidakamizwa, uzoqhubeka amahora angu-48). Symptomatology asishintshi neze, kunzima ngempela ukususa.

Umbono abathengi bezempilo

Iziguli ukhulume "nalbuphine" njengendlela umuthi sasivumela ngempumelelo esikhathini ngemva ukungenelela kuhlinzwa in Oncology. Nakuba side effects luvamile ngempela futhi zivame obonakaliswe bekhanda, ukozela, nokunganaki, ukuphazamiseka wokugaya ukudla. Ngokusho ochwepheshe bezokwelapha, "nalbuphine" (Umyalelo, indlela yokwakheka nomuthi, isimiso umthelela ezichazwe ngenhla) kuyinto analgesic kuhle isifo ngokwanele sina ezihlobene uhlala esezinhlungwini ezinzima.

Kukhona esinye isigaba abasebenzisi izidakamizwa - yezidakamizwa. Lapha, izingxoxo kanye nokubuyekeza ziyancipha umbuzo ukuthi isenzo kufana "Nalbuphine" futhi "Morphine". Kukho konke, njengoba kufakazelwa leli qembu abathengi, kumele kuphetfwe ukuthi kukhanga kangakanani kuwo yezidakamizwa ukwenza "nalbuphine" intengo (ukubala lemanyuwali iziguli ezinjalo kungamukelwa). Umuthi kancane (izidakamizwa kuqhathaniswa kanzima), kungashiwo Nokho uthenge ngasiphi ekhemisi, ngokuvumelana iresiphi. Nokho, amazwi abo 'okusezingeni eliphezulu kuyindida, kodwa ikhefu-up the real kakhulu. "

Ngokwalokhu okungenhla kungenziwa lwaphetha ngokuthi "nalbuphine," Yiqiniso, analgesic ngempumelelo kakhulu. Nokho, bayidayise kuphela kadokotela - futhi kube kufanele. Kusukela ngamunye akhethiwe udokotela umthamo kanye mode kwesicelo - isiqinisekiso sokuthi umphumela izidakamizwa emzimbeni wesiguli uzokhombisa ukuthi unalo igciwane, futhi ingozi nemiphumela engathandeki yalawo maphilisi - ubuncane.