Ukulungiselela "Alfadol-Ca": yokusetshenziswa, isichasiso, analogs kwakwakhe. "Alfadol-Calcium": kuzibuyekezo, izintengo

Uyini izidakamizwa "Alfadol-Ca» ( «Alfadol Calcium")? Yokusetshenziswa, intengo, analogs, kanye nezitatimende ukuqokwa izidakamizwa kuzoxoxwa ngezansi.

Ukwakheka eziyisisekelo, emabhokisini incazelo futhi ifomu

Ukulungiselela "Alfadol Calcium", imiyalelo for ukusetshenziswa lapho kuqukethwe iphakethe eyenziwe amakhadibhodi, ekhiqizwa ngesimo ezithambile gelatin amaphilisi. izingxenye zabo eziyinhloko alfacalcidol ne-calcium, okuyinto ifomu nge-calcium carbonate futhi ekhiqizwa kusuka oyster amagobolondo.

Ukudayiswa ukucabangela nomuthi kuya nentaba emangqamuzaneni okuthiwa Agcwele emabhokisini lephepha.

Pharmacodynamics nomuthi

Ukulungiselela "Calcium Alfadol" (yokusetshenziswa, intengo izidakamizwa kuzoxoxwa ngezansi) iyindlela ahlangene we elawula exchange of calcium ne phosphorus. Ukuthola lokhu imithi ikhuthaza replenishment nokushoda vitamin D3 no calcium abantu.

"Calcium Alfadol" kuhloswe ukuba ngcono 1.25 gidroksikolekaltsiferola lokuhlushwa egazini. Ngenxa yalesi emzimbeni womuntu hhayi kuphela ithuthukisa ukumuncwa kwe-calcium, kodwa futhi phosphate, kanye ngcono aligugu kanye kwehle ithambo resorption. Ngaphezu kwalokho, e seziguli ezithola lokhu ejenti ezigulini benganhlanhlathi okuqukethwe hormone parathyroid egazini, ithambo isuswe futhi ubuhlungu bemisipha.

Izici zomuthi

Kuyini ephawulekayo iwukuba umuthi ngokuthi "Alfadol-Ca»? imfuyo yayo asebenzayo ehilelekile igazi ekunqandeni, ithambo ekwakhekeni, ukudluliswa kwe-nerve amaza, kanye nokwehla imisipha lwamathambo kanye nemithetho inhliziyo.

Kufanele futhi wazi ukuthi nomuthi kubhekwe kusiza sithuthukiswe calcium ukumuncwa kusukela amathumbu, futhi ngcono nesineke kwamathambo.

I kinetics we ejenti calcium-equkethe

Ukunciphisa zomuthi "Alfadol-Ca» okusezingeni eliphezulu. okuhlushwa sakhe esikhulu kunazo zonke esegazini laligujwa ngemva kwamahora angu-9-18. It engena ngokuqondene ethize alpha-globulin, futhi akheka esibindini nge ukwakheka metabolite esebenzayo calcitriol. Ingcenye encani yalokhu le mali akheka e ithambo.

Vitamin D3, oluqukethwe kulesi ukulungiselela, akuphazamisi umsebenzi izinso. Lokhu kukuvumela ukuba babela it nabantu nokwehluleka ukusebenza kwezinso.

nomuthi lubonakaliswa ngesigaba Bile nezinso e esilinganayo.

Izimpawu I-reception-calcium

Yikuphi izifo usebenzisa izidakamizwa "Alfadol-Ca» ( «Alfadol Calcium")? ochwepheshe lezivakashi baye bame kwelokuthi lokhu ikhambi ngokuvamile wabonisa for:

• osteodystrophy kwezinso;
• kwamathambo (menopausal, senile, steroid, idiopathic nabanye), kanye yezinkinga zayo (kuhlanganise bone waphuka);
• hyperparathyroidism futhi hypoparathyroidism (isifo bone);
• ukwehluleka kwezinso imvelo ezingamahlalakhona.

Izimo ukusetshenziswa kwezidakamizwa calcium-equkethe

Kwezinye izimo, imithi kungenzeka ingasetshenziswa "Alfadol-Ca» ( «Alfadol Calcium")? Umhlahlandlela uxwayisa ngokuthi akufanele enqunywe wumgomo, uma unayo izifo elandelayo:

• urolithiasis (okungukuthi, ukwakheka kwe-calcium amatshe);
• Ukwandiswa ukuzwela nesineke uvithamini D3;
• hyperphosphataemia (ngaphandle uma eba ku isizinda hypoparathyroidism);
• amazinga egazi calcium ephakeme;
• olunzulu emsebenzini parathyroid, Vitamin hypervitaminosis D, izimila e bone metastases, osteochondrosis);
• gipermagniemiya;
• ukungabekezelelani okuletha kukhompiyutha noma lamantongomane;
• Zollinger;
• yobudala ezincane.

Ngokunakekela lesi sakhiwo kumele kube ngabantu abaphethwe ukuphathwa izinso, kanye nalabo abasendleleni hemodialysis. Ngempatho eside inani calcium excreted ngu izinso, kumele ihlolwe njalo emavikini ambalwa.

Ukulungiselela "Alfadol-Ca» ( «Alfadol Calcium") incwadi yeziyalezo

Intengo izimali impela high. Wakhe sethula ngezansi.

Umthamo zomuthi kuyakhethwa kuye ubufakazi.

Ngo kwamathambo, i-nomuthi iqondiswa e isamba 1-2 amaphilisi ngosuku.

Lapho hyperparathyroidism futhi hypoparathyroidism, okuyinto ahambisana ithambo, "Alfadol-Ca» kumele kusetshenziswe 1-2 amaphilisi ngosuku.

Ngo osteodystrophy, kanye ezingamahlalakhona ukwehluleka kwezinso ubunjalo izidakamizwa kunconywa ukuthatha 2 Amaphilisi ngosuku.

Isikhathi impatho izidakamizwa kunqunywa udokotela wakho.

uhlangothi imihlola

Wenzenjani ngokwemvelo kungabangela reception "Alfadol-Ca" izidakamizwa ( "Alfadol Calcium")? Manual ithi e imithi oyinikiwe nale ejenti iziguli kungenzeka zingasebenzi kahle kwezinye umsebenzi izinhlelo:

• ipheshana wokugaya ukudla: uhudo, noma ukuqunjelwa.
• umzimba: hypercalcemia. Abantu ne ezinzima izinso umsebenzi bangezwa hyperphosphatemia.
• uhlelo urinary: nephrocalcinosis.
• Yokungezwani komzimba: ukuqubuka, pruritus, urticaria.

ukweqisa izidakamizwa

Hypercalcemia razivshayasya e seziguli ezithola ebulilini zomuthi, ebonakaliswa ukucobeka, ubuthakathaka, ukutubeka komzimba, isiyezi, ubuhlungu bekhanda, ukozela, nomlomo owomile, isicanucanu, ukuqunjelwa, isilungulela, uhudo, ukuhlanza, iziyaluyalu gastro-emathunjini, ubuhlungu besisu, ukhwehlela nobuhlungu bomzimba, ubuhlungu bamalunga, ithambo ubuhlungu, ukulunywa.

With ukuthuthukiswa lezi zimpawu ngokushesha kufanele ayeke bokusebenzisa imithi le.

hypercalcemia Sinzima kudinga ngokweseka izinyathelo zokwelapha lapho umuntu eba nosawoti infusions, futhi kwezinye izimo - ukusetshenziswa corticosteroids futhi isisu.

Ngo overdosage acute Kufanele nifeze ukwelashwa owandulelayo nesineke esebenzisa lavage noma ukuphathwa uwoyela amaminerali. Lezi zinyathelo ukusiza ukunciphisa ukumuncwa futhi sandise excretion of nomuthi ngokusebenzisa emathunjini.

ukuxhumana

Hypercalcemia kubantu ukuthatha glycosides inhliziyo, kuqinisa arrhythmia inhliziyo, ngakho isicelo sabo ngokuhlanganyela kufanele kugwenywe.

Iziguli ehlelekile ethola anticonvulsants futhi barbiturates, ukuze kuzuzwe imiphumela oyifunayo udinga ukwandisa umthamo "Alfadol-Ca» izidakamizwa.

Absorbability zomuthi zingaphazamisa kuthathwe amafutha amaminerali okuhambisanayo (administration ezingamahlalakhona ikakhulukazi), kanye colestipol, colestyramine, sucralfate futhi esiningi antacids aluminium-aqukethe.

Nge ukusetshenziswa ngesikhathi esisodwa nezimali laxatives, antacids, nemithi equkethe magnesium, kanye abantu abaku- hemodialysis, kufanele inake ukuthuthukiswa okungenzeka hypermagnesemia.

I nomuthi "Alfadol-Ca» ( «Alfadol Calcium") analogs kanye nezindleko

Buyisela ukulungiselela asebenzayo kungenzeka izidakamizwa ezifana "oksidevit", "Alpha-D3 Teva", "Alfacalcidol", "Alfadol", "Tevabon", "van-Alpha" nabanye.

Wathi kusho ukuthenga amaphilisi kungabangwa ruble 380-450.

Uphenyo imoto

Ngokusho kwezazi, wathi ekwakhiweni sithuthukisa ukumuncwa emathunjini calcium ne phosphate. In iziguli esingamahlalakhona kwezinso, lokuhlushwa lezi zinto kufanele njalo ukugadwa. Futhi kudingeka ukuqapha lokuhlala phosphate, i-calcium, magnesium, phosphatase ane-alikhali futhi creatinine.

Njengoba for iziguli, bexabana ukuthi "Alfadol-Ca» ubhekana kahle umsebenzi walo. Nokho, kufanele kuphawulwe ukuthi ngokuvamile imiphumela emibi zenzeka ezifana hypercalcemia noma hypercalciuria. Izimo ezinjalo ngempela ukuqedwa kalula ngemikhiqizo ye izidakamizwa zokuqaleka.

Enye Ububi wathi izindlela zihlanganisa izindleko zalo okusezingeni eliphezulu nokungakwazi zisebenzisa labo khona urolithiasis ezinganeni.