Umuthi 'dopegit ": izibuyekezo odokotela

Kuyasiza ekulinganiseni Umfutho izidakamizwa "dopegit". Izibuyekezo lodokotela zithi usebenza masinya. Kuyinto engabizi. Kuthengiswe cishe kuwo wonke ikhemisi. It is uvunyelwe ukuthathwa kwabesifazane abakhulelwe. Umuthi has Izimo, ngakho-ke asikho isidingo ukuphuza ngaphandle kadokotela.

Sakhiwo Ukwakheka

Izidakamizwa "dopegit" (izimpendulo wezazi ziqinisekisa ukuthi lokhu ikhambi kuphela ingcindezi elawulwa kwabesifazane abakhulelwe kanye nomfutho wegazi ophezulu) itholakala amaphilisi. Amaphilisi asemhlophe, umbala kancane lemicu empunga elinamathela othini. Iqukethe mayelana 282 mg isithako esisebenzayo - methyldopa sesquihydrate. Lokhu ubuningi nsé 250 mg methyldopa. izingxenye engeziwe izibhebhe yilezi:

• corn isitashi;
• stearic acid;
• talc;
• sodium carboxymethyl isitashi;
• ETHYL cellulose;
• magnesium stearate.

Tablets zahlanganiswa ngo amabhodlela ngengilazi amnyama yizicucu ayisihlanu. Lezi ziyalezo ebiyelwe ukusetshenziswa.

Isenzo kwemithi zomuthi

Bheka Wegetotropona antihypertensives emaphakathi isenzo "dopegit" amaphilisi (izibuyekezo wezokwelapha abasebenzi bathi lo muthi, abesifazane abaningi baphuze ngesikhathi sokukhulelwa). Uma emzimbeni, le nomuthi is baguqukela metilnoradrenalina ekudalweni-alpha abakhipha umphumela hypotensive ngokwenza izindlela eziningana. Umuthi incipha ithoni nozwela. Lokhu kungenxa ukusebenza kwawo ezinkulu inhibitory presynaptic .alpha.2-yokwamukela.

Umuthi uba neurotransmitter zamanga futhi esikhundleni phezu eziyimpumelelo emsipheni we dopaminergic Dopamine endogenous. Yehlisa umsebenzi renin egazini futhi nomphumela ofanako ukumelana Imininingwane neuropathy. Kumisa synthesis noradrenaline. Yehlisa kumiswa epinephrine, Dopamine, norepinephrine futhi serotonin ngenxa nokucindezela umsebenzi enzyme dopa-decarboxylase.

Ingqikithi asebenzayo - methyldopa - akuphazamisi inhliziyo nomzimba umsebenzi akusenzi okukhipha inhliziyo. Musa avuse ukubonakala tachycardia reflex. It akuphazamisi ijubane filtration glomerular. Ayikho nomthelela kwezinso ukugeleza kwegazi futhi ayinaso ingcindezi ingxenyenamba filterable.

Ngezinye izikhathi lapho ukuphuza umuthi kungase wehlise kwenhliziyo. Imithi incipha ngokushesha umfutho wegazi. Ezimweni ezingavamile, kungabangela hypotension postural.

Ngemva izibhebhe komthamo wokuqala umphumela omkhulu kunayo yonke siyenzeka ngemuva kwamahora 4-6 bese sithatha amahora 12 kuya 24. Umuthi kunganciphisa ingcindezi ngosuku ngokuthatha amaphilisi wesibili noma wesithathu.

ubufakazi

Izinkomba ukusetshenziswa "dopegit" izidakamizwa (izibuyekezo baphikisa ngokuthi izidakamizwa akunankinga ungathenga ngasiphi ikhemisi) kuyinto nomfutho wegazi ophezulu. Lo muthi evame ukunikezwa iziguli abakhulelwe.

Izimo ukusetshenziswa kwezidakamizwa

Lo mbhalo uthi enikeza nomphumela omuhle zomuthi "dopegit" ingcindezi, ukubuyekezwa wezokwelapha. Naphezu kwalokhu, izidakamizwa akukashicilelwa ngoba isifo sokusha kwesibindi ngo esigabeni acute yentuthuko, futhi isibindi sibe sesomile. Ban ukusetshenziswa izifo hepatic kukhona isitho umlando. Izimo ukusetshenziswa kuyinto ekwelapheni mao inhibitor. Awukwazi ukuthatha amaphilisi nokucindezeleka, anaemia hemolytic, futhi isilethikusebenza esigabeni acute yentuthuko.

Musa akunikeze imithi e pheochromocytoma ezingaphansi kweminyaka emithathu ubudala futhi ngozwelo ekhethekile yezingxenye efana izidakamizwa.

Ngokucophelela okukhulu kumele amaphilisi iziguli ezine esingamahlalakhona kwezinso. Lokhu kudinga ukulungiswa umthamo. Ukuze ngaphansi kweso lwezokwelapha ngesikhatsi ukwelashwa, iziguli kufanele diencephalic syndrome, asebekhulile, izingane kusukela eminyakeni emithathu ubudala.

"Dopegit" phakathi nokukhulelwa kanye lactation

Izidakamizwa "dopegit" kabanzi lisetshenziswe zokubelethisa iminyaka engaphezu amahlanu. Ngalesi sikhathi, akukho izigameko zenzeka ngemiphumela teratogenic izidakamizwa embungwini. Ngenxa zokwelapha ifakiwe ingozi akude ukuchayeka amaphilisi on umbungu.

Umuthi ngesikhathi sokukhulelwa kweqa yi-placenta, ngakho bekezela ngaphakathi the "isikhundla" kufanele kube ngaphansi kweso lwezokwelapha njalo. "Dopegit" ngesikhathi lactation (izibuyekezo uqaphele ukuthi odokotela batusa hhayi amaphilisi ephuza kanye nokuncelisa ibele) ludlulele ngaphakathi ubisi lwebele. Ngesikhathi sokwelashwa udokotela belulekwa uphazamise ibele.

Ngo sokukhulelwa, baqale ukwelashwa imithi lamashumi amabili ngesonto sokukhulelwa. Izingane ezizalwa omama ababephathwe "Dopegitom" abazange babe nanoma yiziphi izinkinga. Isithombe esihlukile laligujwa kwabesifazane abakhulelwe abaye benqaba yokwelapha nale ejenti. izingane zabo sazalwa iziyaluyalu zezinzwa ukuthi kwavela ngenxa isikhathi eside-mpilo indlala.

Izidakamizwa "dopegit" ngesikhathi sokukhulelwa:

• Kunciphisa neuropathy semithambo ukumelana.
• Kunciphisa ukukhiqizwa renin.
• It kuholela evamile ingcindezi diastolic.
• Kancane ingena esikhundleni Dopamine - ingxenye ukuthi kwandisa umfutho wegazi.
• It kunomphumela kancane okulalisayo.

Emtholampilo, it is wafakazela ukuthi izidakamizwa ungakulimaza ingane, ngokufaka ngokusebenzisa placenta noma webele ubisi. "Dopegit" kufundiswe ngesikhathi sokukhulelwa (Izibuyekezo bathi lokhu izidakamizwa ayiyona ingozi umntwana) uncoma ukuba linqume lapho inzuzo abazoba umama kakhulu lidlula okungaba yingozi ingane.

Indlela isicelo, umthamo

Medicine "dopegit" lisetshenziswa ngomlomo. Tablets kungukuthi ezokuhlafunwa wageza phansi ngamanzi. Amaphilisi ukuthatha isigamu sehora ngaphambi kokudla noma imizuzu engu-30 ngemva kokuba.

Izinsuku ezimbili zokuqala we imithi belulekwa ukuba aphuze 0.25 g kathathu ngosuku. Umthamo isethwe okusekelwe blood pressure. Ngokukhuthazela ezinhle umthamo liyakhula kancane kancane zonke izinsuku ezimbili. Ngemva kwezinsuku ezintathu ukwelashwa, "Dopegitom" livela umphumela ukukhanya okhalela phansi opholile.

Ukukala iziguli nomfutho wegazi ophezulu kuyinto 0.5-2 g It ihlukaniswe yaba ukwabelana ngokulinganako nokubuthelela kudle kane ngosuku. Umkhawulo umthamo nsuku zonke 3 g

Lapho ethola umthamo wansuku zonke ukwelashwa 2g akunamthelela, futhi ukucindezela kuyehla embi, "dopegit" okunqunyiwe lihambisana namanye izidakamizwa antihypertensive, noma esikhundleni salo omunye izidakamizwa.

Imithi kungenziwa inikezwa iziguli abasebenzisa ekwelapheni nezinye izidakamizwa antihypertensive, kodwa isimo ukususwa kwabo esikhathini esizayo. Kulesi simo, impatho isiqalisile nge 0.5 g ngelanga, kancane kancane, uma kunesidingo, inani izidakamizwa anda ngezikhawu amahora angu-48.

Abantu abadala kufanele uqale ukwelashwa nge 0.125-0.25 g Akufanele kuthathe ngaphezu 2 amagremu ngosuku. Ezinganeni ezineminyaka esukela kwemithathu yemithi izinga onqunyiwe 10 mg kilogram of isisindo sengane ngayinye. Umthamo okuholela ihlukaniswe izigaba eziningana.

Musa kuthathe ngaphezu 65 mg izidakamizwa amakhilogramu esisindo kanye umthamo nsuku zonke ngamunye akufanele idlule iminyaka 3 Ngemva kwezinyanga ezintathu usebenzisa "Dopegita" kukhulunywa ngayo kaningi ukubekezelelana emuthini. Kulokhu, eminye ebekiwe isisu futhi antihypertensives.

"Dopegit" Medicine: yokusetshenziswa ngesikhathi sokukhulelwa

Izibuyekezo Ochwepheshe uqaphele ukuthi amaphilisi abazenzi kalula futhi cishe akukho imiphumela emibi. Ngenxa yalokhu, avame ebekiwe esikhathini sokukhulelwa. Umuthi has Izimo ezimbalwa futhi ayinayo imiphumela anobuthi embungwini. Le mpahla kwenza kube nokwenzeka ukuba athathe abakhulelwe yakhe isikhathi eside, kwaze kwaba ukulethwa. Ngo sokukhulelwa, amaphilisi ukwelashwa kufanele kuhambisane kokuqondisa kukadokotela sika nokuqaphelisisa ukuhlolwa igazi.

Kuthiwa ngokushesha kuholela ingcindezi evamile "dopegit" ngesikhathi sokukhulelwa, ukubuyekezwa. Umthamo kunqunywa ngamunye udokotela. owesifazane Okokuqala wahlola. Khona-ke, ngokusekelwe imiphumela cwaningo kushintshwe umthamo. Ngokuvamile ekuqaleni ukwelashwa nge iphilisi elilodwa 250 mg ngosuku. Kubukeka sengathi izidakamizwa ibekezelelwe. Ngokukhuthazela ezinhle kancane kancane ukwandisa umthamo ngezikhawu izinsuku ezimbili. Ukuthatha izidakamizwa nje ingcindezi eza emuva evamile. esiphezulu I umthamo wansuku zonke kwabesifazane abakhulelwe - 2 Iminyaka

"Dopegit" ladies kule sikhundla unikezwe indaba nje kuphela ezimweni ngekucindzetelwa kakhulu. Ngokuvamile, trimesters wesibili nowesithathu. Umuthi kuyadingeka ekukhulelweni ukuvimbela preeclampsia ifike sekwedlule isikhathi, i-fetus okhula evamile.

Umuthi Kusiza ekudambiseni ukucindezela ngokucacisa 10-20%, okuvumela lady abakhulelwe evamile ukuzizwa.

side effects

Tablets "dopegit" Izibuyekezo abakhulelwe kubhekwa izidakamizwa engcono usimamise blood pressure. Naphezu kwalokhu, izidakamizwa kungabangela enjalo engemihle ezifana ukozela, ukucobeka, ukudideka. Uma uthola imithi ngezinye izikhathi ivela ukukhubazeka ebusweni, isiyezi, Gait ongagxilile, parkinsonism. Kusukela uthatha imithi ye imbangela ikhanda, orthostatic umfutho wegazi ophakeme, myocarditis, bradycardia, kukhuphuke senhliziyo futhi angina. Kwakukhona edema neuropathy, ukuminyana, pericarditis.

Therapy "Dopegitom" yavela glossalgia, kome umlomo, uhudo, ukuhlanza reflex, nesifo. Sibekezele amaphilisi uma nithatha ungase uphazamise hepatotoxicity, jaundice, futhi pancreatitis. Fixed leukopenia, agranulocytosis, anaemia hemolytic futhi thrombocytopenia.

Umuthi kungabangela myalgia, arthralgia, futhi gynecomastia. Avuse galactorrhea, amenorrhea futhi hyperprolactinemia. Nciphisa libido futhi potency.

Ezimweni ezingavamile, ukwelapha imfiva iphutha, Lyell Syndrome. iziguli Disturbed awahlabi, ukuqubuka. Kube ukuminyana acinene zivuvukale nezindlala salivary.

eshalofini yokuphila, isitoreji indlela

Umuthi ekhiqizwa e-Hungary ngu "EGIS". Umuthi kumele agcinwe ezingeni lokushisa kusuka +15 ukuba + 25 ° C. Endaweni uvikelekile ezintweni ilanga nezingane. Impilo eshalofini amaphilisi - iminyaka emihlanu. Imithi ayikwazi ukusetshenziswa ngemva kwalesi sikhathi.

Izindleko kwemithi

Kunconywa kudokotela ngaphambi kokusebenzisa "dopegit" imiyalelo ukulungiselela ukusetshenziswa. Uphenyo odokotela bathi lokhu umuthi ephephile yazo zonke ukunciphisa ingcindezi, ngakho-ke, it is ebekiwe kwabesifazane abakhulelwe.

Imithi zingathengwa cishe njalo ikhemisi. Intengo amaphilisi 50 250 mg nxazonke 200-250 ruble.

Uphenyo odokotela

Odokotela bavame ukunquma "dopegit" amaphilisi ngesikhathi sokukhulelwa. Uphenyo odokotela abonisa ukuthi izidakamizwa akunamthelela inhliziyo. Musa avuse ukubukeka tachycardia futhi akusenzi okukhipha inhliziyo. Ngokusho kwabo, umuthi kwehlisa umfutho wegazi ngokunciphisa ngevolumu ukugeleza kwegazi, kanye ukushuba ukushaya kwenhliziyo.

Odokotela avumele ukusetshenziswa imithi ngesikhathi sokukhulelwa, kodwa ukhumbule ukuthi udinga ukuwaphuza kuphela enemibandela. Bheka ku-lwemithi ephephile. Kuthiwa yini amaphilisi angenza umonakalo kakhulu somntwana ongakazalwa futhi ezithinta ukuthuthukiswa yayo. Umuthi uyasebenza emini, okuyinto inzuzo eyengeziwe ngakho.

Odokotela ukholwa ukuthi leli imithi ababuthakathaka futhi cishe ubani ngaphandle kwabesifazane abakhulelwe, ke akukashicilelwa.

Medicine "dopegit" ngesikhathi sokukhulelwa: Izibuyekezo

Mhlawumbe omunye izidakamizwa ezivamile ebekiwe ngesikhathi ukhulelwe "dopegit". Abesifazane abakhulelwe abakhathalela-high blood pressure, ukuwaphuza waze wabeletha. Bathi it kunciphisa ingcindezi ngokushesha nangempumelelo. Bonke labo wathatha lawo amaphilisi zalujabulela umphumela wabeletha izingane enempilo. Bona wazi ukuthi izidakamizwa akunamthelela kwengane esiswini, kodwa kunalokho, ukusiza ukuvimbela preeclampsia kamuva, kunomthelela ukuthuthukiswa evamile umntwana utero.

"Dopegit" ngesikhathi sokukhulelwa kanye nokubuyekeza ezimbi kubangelwa. Laba bantu kusebenta ongaphakeme zomuthi. Bathi it kwehlisa umfutho wegazi futhi ezimbi neze kuyasiza. Kungadala ubuthakathaka futhi ukozela. Abanye bangase bangathandi intengo kanye iqiniso lokuthi izidakamizwa kufanele esiphuza isikhathi eside.