Umuthi 'interferon-alpha "

I nomuthi "Interferon-alpha" kuyinto namagciwane immunomodulating izidakamizwa ngoba isicelo sendawo kanye nabangaphandle. Lokhu - inhlanganisela subtypes eziningana-alpha interferon kusukela leukocyte. Umuthi has namagciwane, antiproliferative nomphumela immunostimulating.

Umkhiqizo "Interferon-alpha": yokusetshenziswa (izimpawu, contraindications, umthamo)

Umuthi kuboniswa kwezokuphatha parenteral yezifo ezifana:

- ukusha kwesibindi kohlobo B no-C,

- warts zangasese;

- myeloma amaningi ;

- enoboya iseli wegazi;

- lymphoma;

- mycosis fungoides;

- kwezinso cell carcinoma kanye nabanye.

Isikhathi esining impela, umuthi isetshenziswa rectally ekwelapheni esingamahlalakhona noma sibi isifo sokusha kwesibindi kohlobo ezibangelwa amagciwane. Intranasally isicelo nokwelashwa kwezinkinga umkhuhlane.

"Interferon-alpha" is contraindicated kubantu abane ezinzima organic isifo senhliziyo, kwezinso ezinzima noma umsebenzi hepatic, isifo sokuwa, iziyaluyalu we CNS, i-hepatitis ezingamahlalakhona futhi ziphathwe yisifo sokuqina. Umuntu angeke alithole ukuthatha izidakamizwa njengoba kulezo ziguli abahlushwa isifo sokusha kwesibindi okungamahlalakhona, yathela ukwelashwa ahlukahlukene immunosuppressive (ngaphandle GCS), abantu abanezifo yegilo futhi baqinisekisa ukuthi uzwela kuqiniswa ukuze isakhi esiyinhloko esebenzayo zomuthi (interferon-alpha).

Ngokuqondene ngomthamo, umthamo, imvamisa yokuphathwa nobude asethwe ngamunye. Konke lokhu ngqo ehlaselwe izinto ezifana degree of isifo, inkomba, umzila yokuphathwa kanye impendulo eyodwa isiguli.

Ukulungiselela "Interferon-alpha": imfundo manual (side effects, ekuxhumaneni izidakamizwa kanye nemiyalelo ekhethekile)

Ukuze abaphathi parenteral imiphumela izidakamizwa ohlangothini zenzeka kanengi ukudlula kanye nezinye izindlela zokuphatha. Kungase kube anjalo ezahlukene Umkhuhlane imihlola (uphethwe yikhanda, imfiva, ukukhathala) futhi iziyaluyalu wokugaya ukudla (nesicanucanu, ukungakuthandi ukudla, ukuhlanza, uhudo ngezinye izikhathi); zenhliziyo (arrhythmia, hypotension); CNS (kahle ukwazi, ukozela, ataxia). Ngaphansi ezivamile emva kokwelashwa "Interferon-alpha" kungenzeka isikhumba ukusabela (isikhumba esomile, Alopecia, ukuqubuka kwesikhumba, i-erythema).

Uma sikhuluma izidakamizwa ekuhlanganyeleni zomuthi namanye amanxusa Kumele kuqashelwe ukuthi interferon bathambekele zivimbela umzimba oxidative esibindini, kungaba ke ibe sengozini biotransformation izidakamizwa ukuthi basuke akheka ngale ndlela. It is hhayi Kunconywa ukusebenzisa "Interferon-alpha" ngokuhlanganyela ACE inhibitor, kusukela isinyathelo haematological synergism kungenzeka, futhi-paracetamol (kungandisa umsebenzi enzyme kwesibindi).

Phakathi nenkathi yokukhulelwa, le izidakamizwa ingasetshenziswa kuphela iseluleko udokotela, futhi kuphela uma inzuzo engaba kwabesifazane idlula ingozi Cishe ingane.

Kakhulu ngokucophelela, umuthi isetshenziswa abantu ababenezinkinga ithuba ukuhambisa isilethikusebenza. Abantu abadala bangase babe imiphumela emibi phezu isimiso sezinzwa esiyinhloko. Ezimweni ezinjalo, impatho ngokuvamile inqanyulwe.

Iziguli hepatitis C abathola ukwelashwa "Interferon-alpha" ungase uphawule yegilo ukungasebenzi, okuyinto ukuzwakala hyper- noma i-hypothyroidism. Ngakho, ngaphambi kokuqala Inkambo yokwelashwa kuyadingeka ukuze kutholakale izinga we-hormone yegilo-inkanuko egazini bese uqala ukusebenzisa izidakamizwa kuphela endabeni hormone evamile serum.

Isexwayiso! Lolugwalo enikeziwe ukuze yazi nge isidakamizwa. Ngaphambi kokuqala ukuthatha inkambo ke, ukuxoxa nodokotela wakho, ngubani ngamunye ukunquma isilinganiso ezifanele kanye nesikhathi sokwelashwa. Funda ngokucophelela umkhiqizi isichasiselo.