Umuthi 'Warfarin'. Yokusetshenziswa

Umuthi 'Warfarin "imiyalelo ukusetshenziswa libhekisela esigabeni anticoagulants ka engaqondile senzo. Umuthi uyakwazi zivimbela synthesis ekunqandeni izici (vitamin K-kuncike) kanye amaprotheni C no S esibindini. Kahle anticoagulant umphumela waphawula ngosuku lwesithathu noma lesihlanu ngemva emizameni yokuthuthukisa yokwelapha kanye sinqanyuliwe emva kwezinsuku ezintathu kuya kweziyisihlanu ngemva umthamo wokugcina. Umuthi itholakala ifomu tablet.

Kunconywa uma usebenzisa imithi "Warfarin" Ukudla kuhilela nokugcina cishe esilinganayo vitamin K ekudleni

ubufakazi

Umuthi kuboniswa ngenxa nokwelashwa thrombosis futhi thromboembolism. Ngu izinkomba ngoba izidakamizwa "Warfarin" imfundo manual uyalandisa thromboembolism ne-acute thrombosis emithambo yegazi, embolism yamaphaphu, ukuphinda isilethikusebenza, thrombosis nasezinkingeni ezilandela ngemva kokuhlinzwa. Ukulungiswa ezinqunyiwe ekusebenziseni ukususwa thromboembolic noma thrombosis kuhlinzwa (njengesilwane izindlela ezengeziwe) ngoba fibrillation atrial (cardioversion kagesi), relapsing (re) vein thrombosis, embolism ku Umthambo yamaphaphu. Kusho "Warfarin" imfundo manual uncoma ngalezi zitho semithambo valve inhliziyo (okuyinto uvunyelwe nokusetshenziswa kuhlanganiswe of acetylsalicylic acid). Ngaphezu kwalokho, lo izidakamizwa ezinqunyiwe thrombosis, palsy, nemithambo yegazi yenhliziyo kanye neuropathy, kanye nokuvinjelwa yesibili thrombosis noma embolism ngesikhathi nokucwayiza i atrial noma ngemva infarction.

Izimo imanuwali izidakamizwa "Warfarin" imfundo libabiza ukungabekezelelani ngabanye, kwezinso noma isifo hepatic ezinzima, ukopha acute, umfutho wegazi ophakeme (uhlobo ezisindayo), exacerbation izilonda esiswini noma duodenum, oluhambisana diathesis, ukuntuleka S futhi C amaprotheni, ukuba umlutha wotshwala, ukopha palsy, kwezinso umsebenzi esingamahlalakhona, acute DIC, thrombocytopenia. Khomba izidakamizwa ngesikhathi sokukhulelwa.

Okuvame kakhulu izigameko ezingezinhle ezavela ngesikhathi nokuphathwa izidakamizwa "Warfarin" is ukopha. Ezimweni ezingavamile, kukhona necrosis kwesikhumba, ama-enzyme isibindi yanda, uhudo, eczema, ukuqothuka kwezinwele, vasculitis.

Isikali

Umuthi kuboniswa kwezokuphatha ngomlomo. Kunconywe isicelo esisodwa, esikhathini esifanayo. Umthamo kokuqala - amabili nesigamu kuya angu amahlanu usuku nosuku.

Okwalandela nokushintsha kokudla nokufakwa lwemithi "Warfarin" (INR noma isikhathi prothrombin lapho lokhu kunakwe) inqunywa ngamunye. Ezikhathini ezimbili kuya emthonjeni kumele andisa isikhathi prothrombin. Kulesi simo INR (isilinganiso kwesejwayelekile international) kufanele sifinyelele (kuncike zokugula ematfuba ukopha, thrombosis ingozi) 2.2-4.4.

Ukuze ezigulini esezikhulile noma sikuleso simo sokuba buthaka ebekiwe ngemithamo engezansi izidakamizwa "Warfarin".

Ngaphambi esondela operation (esimweni nezici ezithile ukuze ukuthuthukiswa yezinkinga thromboembolic) yokwelapha iqala izinsuku ezimbili noma ezintathu ngaphambi kokungenela.

Ngo-acute ukwelashwa thrombosis Kwenziwa lihambisana izidakamizwa "Heparin" kuze kube isikhathi lapho umphumela anticoagulant akuyona wabonakaliswa ngokugcwele (ngokuvamile hhayi ngaphambi ngosuku lwesithathu futhi lesihlanu).

Isikhathi yokwelapha kuncike isimo lesiguli.

Ngaphambi ekuqaleni ukwelashwa kuyadingeka ukucacisa Inkomba INR (ngokuhambisana isikhathi prothrombin, banikezwe ukuzwela Coefficient thromboplastin).

Ngokusho iziguli eziningi, imithi "Warfarin" akuyona kuphela ngempumelelo, kodwa futhi elula, ngoba sidinga ukuthathwa kanye ngosuku kuphela. Ngaphezu kwalokho, kusho kwamukeleka kahle, side effects awavamile. Nokho, ngaphambi kokusebenzisa umkhiqizo wakho, kumele uxhumane nge onguchwepheshe, futhi ufunde imiyalelo ngokucophelela.