Yokwelapha Photodynamic in Oncology: emihle nemibi

Umdlavuza ungomunye yezindawo zokuqala phakathi lokufa labantu. Eminyakeni yamuva, ngokucijile isibalo sezikhungo umdlavuza ukuthi uxilongwe ezigulini. Ngeshwa, Awunawo imikhawulo yobudala - lesi sifo sihlasela kokubili abadala kanye Spares nezingane.

Esikhathini sethu, zasebenzisa izindlela ezintsha ezingasho yokwelapha abantu abanomdlavuza, imithi seyithuthuke kulokhu isivele kude phambili. Enye indlela ezinjalo ukwelapha photodynamic in Oncology. Nale ndlela, sizofunda kancane kulesi sihloko.

Umqondo yokwelapha photodynamic

Le ndlela yokwelashwa yigama esifushanisiwe ka PDT futhi empeleni yayo ukusetshenziswa amaqembu ukukhanya ezithile izidakamizwa abizwa ngokuthi photosensitizers. Lapho edalulwa ukukhanyisa ketshezi izidakamizwa zanqwabelana isimila esinomdlavuza iqala ukuba deleteriously kuthinte amaseli ayo.

Kuye kwasendaweni izimila, ukulungiswa kungenzeka iqondiswa lingene egazini noma isetshenziswa ngaphansi kwesikhumba. Ngemva esifushane ke amuncwa umzimba kwezicubu, bese leli cebo iqondiswe wokukhanya.

Ake sihlole ukuthi yini Biophysics yayo. yokwelapha Photodynamic in Oncology emva ukukhanya ugongolo Falling kuyehla kube nokuxhumana chemical umoya-mpilo, futhi ngenxa yalokho, amaseli umdlavuza ayafa. Uma yokwelapha enjalo kuyadingeka ukususa izitsha ezincane igazi, wayencisha yokudla lwesimila.

Izigaba yokwelapha PD

yokwelapha Photodynamic in Oncology kuhlanganisa izinyathelo ezimbalwa:

1. Isingeniso niqaphelisa isixazululo ngemithambo yegazi.
2. Ukubuthelela izidakamizwa ezicutshini ehlaselwe umdlavuza. Banikezwe ezihlukahlukene kwezicubu nezidakamizwa, lesi sinyathelo ngezinye izikhathi ihlala izinsuku ezimbalwa. Kwakuthinta ngalesi sikhathi, izazi kutholakala ukuthi uphethwe yini isimila ngesisekelo degree of lokuhlushwa sensitizer.
3. Isinyathelo isimila ngemisebe laser imishayo. Uma umdlavuza kujule kakhulu, imishayo esetshenziselwa ukulethwa tube LED. Ngaphansi kwethonya laser iqala yokusabela anobuthi, okuholele umdlavuza amangqamuzana efa, kuyilapho izicubu eduze enempilo ayiphazamiseki.
4. Isinyathelo kwamazinyo izicubu umdlavuza ukulungisa futhi equliswa wezakhi. Ubude besikhathi bungaphezu cishe inyanga.

Njengoba lisetshenziswe ukwelashwa photodynamic in Oncology

Lokhu uhlobo yokwelapha iwukuba ukwenza ngcono izinga lempilo iziguli. PDT ayinakho ukubonakaliswa eside negative, kodwa hhayi njengoba kabanzi kuwo wonke amazwe.

Photodynamic Ukwelashwa Oncology eMoscow isetshenziswa kusukela 1998. Njengamanje, enhloko-dolobha zikhona 5 amahhovisi, okuyinto afeze le nqubo. Abangaba yizinkulungwane ezingamashumi 2. Iziguli babephathwa ngale ndlela.

I-Cancer Dispensary emitholampilo №1 lakhiwe futhi esetshenziswa contact PDT. Laser ngemisebe uqhutshwa ngendlela kwenza ukwandisa sokungena wale misebe ukujula 2 cm.

Izinzuzo lokhu indlela yokwelashwa

PDT - indlela ezintsha yokulwa umdlavuza kanye okwakheke precancerous. Okwamanje kusaqalwa of Oncology yayo azame ukusebenzisa yokwelapha njengokungathi photodynamic in Oncology has a inzuzo enkulu:

• Kungenzeka ukuba nomthelela amangqamuzana omdlavuza kuphela.
• Iziguli kalula ukubekezelela inqubo ngasiphi yobudala.
• Ukwelashwa kunomphumela mnene phezu kwezitho nezicubu ehlaselwe umdlavuza.
• Ngo umdlavuza inqubo isikhumba unika 100% Imiphumela ngempumelelo.

• Umdlavuza womlomo wesibeletho, le ndlela iyona ngempumelelo kakhulu, njengoba ikuvumela ukuba ugcine uhlelo zokuzala sowesifazane.
• Ukwelashwa engenziwa esigulini esingalalisiwe esibhedlela.
• kungenziwa kuyaphindwa uma kunesidingo.
• It has no yezinkinga letindzala.
• Ukusebenzisa le ndlela, kungenzeka ukususa izimila kanzima ukuze afinyelele izindawo.
• Ngesikhathi inqubo isiguli bayazi.
• Le ndlela kobuhlungu ngokuphelele.
• yokwelapha Photodynamic in Oncology ingasetshenziswa njengendlela indlela ezimele ukwelashwa, futhi njengengxenye ukwelashwa.

Indlela kunemiphumela kubhujiswa amangqamuzana omdlavuza, kanye virucidal (okudiliza womuntu papilloma virus), fungicidal, amagciwane kanye immunomodulatory. Ukuba khona nje zalelo nani elikhulu izinzuzo okwenza kube ethandwa.

ukulinganiselwa

Ngaphandle izinzuzo eziningi, indlela has nezihibe:

• Ukwelashwa kunomkhawulo ukufinyelela yokukhanya. Lokho amenable ekwelashweni ingxenye ukuthi itholakala ngqo ngaphansi kwesikhumba. Ngenxa yalokhu, akunakwenzeka ukuba asebenzise indlela ukuqeda amangqamuzana omdlavuza, okuyinto lapho esezinzile cishe yonke kwezitho nezicubu.
• Ngemva kwesikhashana photosensitizers agcinwayo nokuzwela ekukhanyeni.

Kodwa konke okungenhla kubonisa futhi ukuthi imishanguzo photodynamic in Oncology has a amaphutha amancane kakhulu.

Izinkomba ngokusetshenziswa indlela

Kufanele kuqashelwe ukuthi PDT isetshenziswa hhayi kuphela ukususa izimila anomdlavuza, kodwa nezalo nokwelashwa psoriasis, vitiligo, lupus cutaneous kanye nezinye izifo. yokwelapha Photodynamic isetshenziswa ukuze kulahlwe ezihlukahlukene umdlavuza kanye therapy precancer. Kuyinto ngempumelelo e izifo iso nezinkinga dermatological.

Ngaphezu kwalokho, besebenzisa le ndlela babanikeze ukwelashwa amanxeba okungezona ephulukisa kanye nezilonda trophic.

Ongenayo sifanekise inqubo PDT

yokwelapha Photodynamic in Oncology has Izimo, kodwa ezincane. It is hhayi kwenziwe:

• uma kukhona zokugula we kwezinso nesibindi;
• izifo decompensated kohlelo zenhliziyo;
• ngesikhathi ukuzwela ngokweqile emuthini;
• izifo igazi.

Indlela is contraindicated ngesikhathi ukuzalwa kanye lactation.

yokwelapha Photodynamic in Oncology kufanele asetshenziswe kuphela emva kokukhuluma nodokotela, ukuze bakwazi ukubona zonke Izimo ezikhona.

Ahamba kahle amalungiselelo lisetshenziswe ukwelashwa

Sokufeza le ndlela yokwelapha oncologists zisebenzisa izidakamizwa ukuthi zingahlukaniswa ngamaqembu amabili:

1. sensitizers isizukulwane sokuqala, ne porphyrins.
2. lesibili isizukulwane photosensitizers.

Kungakhathaliseki iqembu, ukuze isihloko izidakamizwa izimfuneko ezikhethekile:

• It has impahla ukuba agxilise sibaningi e umdlavuza futhi engenzi ukungena inyama ephilile;
• emva inqubo ngokushesha excreted emzimbeni has a ubuthi ongaphakeme;
• Akukona buthelela esikhumbeni;
• Kuyinto ukumelana isitoreji kanye nokuphathwa emgudwini wegazi;
• It has izakhiwo Fluorescent.

Uhlolojikelele izidakamizwa ngenjongo PDT

Indlela yokwelapha photodynamic in Oncology livame ukusetshenziswa nge "Photofrin" izidakamizwa. It ivuswe ngu umbala obomvu. Futhi ulisebenzise ekwelapheni kwale mibandela elandelayo:

• Umdlavuza amalaka. Emva inqubo isiguli uzizwa kangcono, ikakhulukazi sibonisa ukusetshenziswa kwezidakamizwa, lapho isimila ifinyelela usayizi cishe ekuvimbeni amalaka, futhi ukwelashwa laser abakwazi ukubhekana naso.
• emphinjeni Barrett sika. Umuthi usetshenziswa njengesibonelo ukwelashwa kokuvimbela ukuvimbela ukuthuthukiswa umdlavuza.
• umdlavuza wamaphaphu.

Aminolivulinovaya acid isetshenziswa endabeni keratosis senile. It sisetshenziswa ngqo isikhumba futhi ivuswe ngu okwesibhakabhaka. Singasetshenziswa kuphela ebusweni nasekhanda.

Zikhona nezinye izidakamizwa, kodwa zisetshenziselwa ingasaphathwa njalo.

Inqubo ukwelashwa usebenzisa "Photofrin"

I nomuthi sihloko ngemithambo yegazi zifakwa emzimbeni. Ukuthola ngaphakathi, uqala ugxile amangqamuzana omdlavuza nje kuphela kodwa futhi enempilo ukuze umzimba. Ngokuphelele amaseli enempilo zingakapheli izinsuku ezimbalwa ukuze kucace ngokuphelele ketshezi, futhi izohlala e umdlavuza.

Kodwa uma uqhubeka ukwenza lutho, akukho lutho Kuzokwenzekani yesimila. Ukusabela iqala kuphela uma kukhona ukuchayeka ukukhanya inamandla athile, aba amangqamuzana.

Uma ufuna ukufeza inqubo yokwelapha umdlavuza wamaphaphu, khona-ke lokhu kwenziwa kusetshenziswa bronchoscope ukuhlaba zingene Ubuningi bamahora ku izicubu abathintekayo. Doctors for laser PDT isetshenziswa ephethe namandla amancane, ngakho asikho ukusha kwezicubu Ngeke usathola.

Ubude besikhathi sokwelashwa incike indawo isimila nendlala okuthiwa i Ubukhulu bayo (ngokuvamile kuba kusuka 5 kuya 45 amaminithi). amangqamuzana afile nezicubu zinyamalale ezinsukwini ezimbalwa. Ngemva ukuhlolwa, uma kudingeka, inqubo yesibili.

Sicela uqaphele ukuthi imishanguzo nokusetshenziswa "Photofrin" hhayi konke kuvunyelwe, it is contraindicated uma kukhona:

• fistula phakathi emphinjeni futhi bronchi;
• isimila esinomdlavuza ukuthi isakazwa imikhumbi emikhulu igazi;
• esiswini noma ngemithambo lakhulisiwe;
• njengemithi yokungezwani komzimba nokuthile emuthini.

Yonke imibuzo ngempela ukuxoxa nodokotela wakho ngaphambi kokuba inqubo.

imiphumela emibi PDT

Okuvame kakhulu ohlangothini umphumela inqubo usebenzisa "Photofrin" iyona ukuzwela anda ukuze ukukhanya. Ngezinye izikhathi ngaphezulu ukuvuvukala kusayithi ukwelashwa futhi soreness encane.

Uma izidakamizwa engena umzimba, ke aqoqana kwamangqamuzana nezicubu ezinsukwini ezimbalwa futhi ngezinye izikhathi amasonto emva kokwelashwa angahlala kumasistimu amaseli. Sonke lesi sikhathi, iso lesiguli kanye isikhumba ebucayi ukuze okukhanya. Kusukela izibani izindawo olungavikelekile ziqala ukuba sikhukhumale ibhamuza kwamaminithi ambalwa.

Lokhu ukuzwela kungaba iqhubeka izinyanga eziningana, konke kuncike izici umzimba. Sizoba sonke isikhathi ukugwema elangeni, kodwa akusho ukuthi kudingeka ahlale endlini emnyama. emini Dosed kusiza ukubhujiswa izinto kumaseli futhi ikhuthaza ekusimameni.

ukuzwela yenu kuyovumelana kancane kancane ukushona, ungabheka it out, kodwa hhayi ngaphambili kweyodwa ngenyanga emva kokwelashwa photodynamic.

Iqhaza imiphumela kungaba ukuvuvukala endaweni yokwelapha. Uma inqubo eyenziwa emphinjeni, okokuqala kuyoba nezinkinga nge nokugwinya, futhi ngemva zokukhwabanisa yamaphaphu - moya owawusele kuyo. Phezu ukuthola izimpawu ezinjalo ngokushesha kufanele afune usizo lwezokwelapha. Eminye imiphumela emibi ibandakanya lokhu okulandelayo:

• isicanucanu, ukuhlanza, ikhanda elibuhlungu, hiccups - uma PDT wenziwa emphinjeni;
• iphika, ukuthuthukiswa Ukucinana kwemigudu yomoya emaphashini noma inyumoniya - kungaba emva kokwelashwa ukukhanya.

Zonke izinhlobo ezinjalo kudingeka azise udokotela.

Izincomo emva kokwelashwa

Ungagwema eziphawuleka side effects emva kokwelashwa, uma wazi indlela yokulungiselela futhi ukuba ziziphathe kahle ngemva kokuhlinzwa. Ukuze wenze lokhu, landela lezi zincomo:

1. Ukuya esibhedlela ukulapha photodynamic, kubalulekile ukuba avale wonke amafasitela indlu lamakhetheni, kanye ukubona ukuthi shades isibani avikelekile noma ngenye indlela.
2. Thatha nawe esibhedlela ngempela izibuko, isigqoko (mhlawumbe isigqoko esinompheme omkhulu) ukuvikela ubuso. Nezingubo kufanele abe izinto ezinemikhono emide, nezimbadada ezinyaweni zakhe - noma amabhulukwe amasokisi (esimweni esinjalo, ithemba umuthi ongakuvikela elincane).
3. Emva inqubo, ezinsukwini ezingu-30, kungcono ukuba kwenzeke emgwaqeni emini bebade, futhi qiniseka ukuvikela isikhumba sakho ngisho liguqubele uma uphume.
4. Zonke ezimweni eziphuthumayo kanye eziphuthumayo, kuyinto efiselekayo ukudlulisela kusihlwa.
5. Ikhaya Ukufundwa kubalulekile ukuvikela amehlo kusukela ekukhanyeni ngqo kusukela isibani.
6. Ngemva ukugeza akukafaneli kutsi sisetjentiselwe kufundzisa dryer - umoya oshisayo kungase kushukumise ketshezi ezisele amaseli bese kubangele ububomvu futhi eshisa.

Uma ulandela zonke lezi izincomo, therapy photodynamic in Oncology sizobonisa ngempumelelo enkulu kanti isiguli uyojabula umphumela.

ngabuka

Noma iyiphi indlela yokwelashwa ayikwazi ngokulinganayo esetshenziswa kahle ukwelapha zonke iziguli. Kodwa ukwelashwa photodynamic in Oncology Izibuyekezo kuyinto ikakhulukazi okuhle. Iziguli bathi emva kokwelashwa isimo sabo ngokuphawulekayo ngcono, kuyiqiniso ikakhulukazi umdlavuza wesikhumba, nezinye izifo zesikhumba. Ngemva PDT cishe akukho izibazi, isikhumba kuba wezindlu.

Iziguli ukubika ukwelashwa ngaphandle kobuhlungu, inani elincane engemihle. Kodwa kufanele kuphawulwe ukuthi cishe zonke iziguli ukhulume ezwela kakhudlwana ngemva kokuhlinzwa. Kufanele ugweme ukukhanya okukhulu futhi enokwethenjelwa ukuvikela amehlo akho kanye isikhumba kusukela naye.

yokwelapha Photodynamic in Oncology has impendulo engeyinhle kuphela kulabo abangazange athobele iseluleko udokotela kanye akazange ukudalula comorbidities ekhona. Kufanele kuqashelwe ukuthi umdlavuza amalaka noma wamaphaphu yokwelapha eziyinkimbinkimbi, futhi ngemva kungase unezinkinga ukugwinya nokuphefumula kanzima, kodwa into yesikhashana ukuthi ngeke kancane kancane.

Ngemva ukwelashwa, cishe zonke iziguli weneliseka yalokho, ikakhulukazi uma inqubo yenziwa onguchwepheshe abaqeqeshiwe. Ngakho, ukwelashwa photodynamic in Oncology e Novosibirsk watadisha emangalisayo UProfesa Sergey Danilovich Nikonov. Waba yokwelapha photodynamic ubuchopho, kanye indlela pleurisy yokwelapha kantseromatoznogo, kulesi senzakalo lapho ukhiphe izincwadi eziningi futhi amaphepha isayensi.

Kwamanye amadolobha, kukhona imitholampilo ukuthi ngokukhethekile nokwelapha umdlavuza kuchazwe. yokwelapha Photodynamic in Oncology e Krasnodar etholakalayo emitholampilo Dispensary oncologic №1. Lokhu isikhungo sokwelapha ifakwe ubuchwepheshe bamuva, ngakho iziguli impumelelo ukwelashwa akunakungatshazwa.

Ngenhlanhla, manje ngisho yilesi sifo esesabekayo, njengesifo somdlavuza, akuyona umusho. Into ebaluleke kakhulu - ukumambula ke esigabeni lapho ungakwazi ukubhekana ngokuphumelelayo nakho-ke. Futhi konke lokhu, khona-ke ufuna ngonanzelelo impilo yabo futhi alandele nokuhlolwa odokotela njalo. Zinakekele futhi uhlale unempilo!