Kuyini neurosyphilis? Izimpawu, amafomu, ukwelashwa, imiphumela

Ngaphansi ugcunsula libhekisela Venereal isifo semvelo, lokuyindlela iphula ezinye isitho izinhlelo zangaphakathi. In the ukungabikho ukwelashwa abanekhono emva kwesikhashana kungase ukuthuthukisa neurosyphilis, libhekene Ukungena ukutheleleka ku isimiso sezinzwa. Kuyingozi kakhulu impilo yabantu zokugula, esongela ukukhubazeka Imininingwane noma ukufa.

Kuyini neurosyphilis?

Ngaphansi neurosyphilis libhekisela esithathelwanayo isimiso sezinzwa esiyinhloko yomuntu. Ukuthuthukiswa sifo sibangelwa kwema- agent umzimba causative of ugcunsula. Lesifo kungenzeka abahilelekile sokugembula kuzo zonke izingxenye zesimiso sezinzwa yobuchopho ziphethe izinzwa. Emtholampilo, lesi sifo livezwa eziningi iziyaluyalu zezinzwa: isiyezi, buthakathaka kwezicubu, ukukhubazeka, ukuquleka, komqondo.

Ngokokuqala ngqá mayelana ugcunsula ukhuluma Ephakathi. Ngalezo zinsuku alchemy engazi ukuthi neurosyphilis. Wahlushwa isifo, kubahlanganyeli Zokholo. Phakathi Eminyakeni Eyikhulu neMpi ugcunsula kungenjalo ngokuthi isifo isiFulentshi, ngokuthi iBritish "baletha" ke esuka ezwekazini. Emashumini eminyaka adlule, ugcunsula kwakubhekwa njengesibusiso zemisho esithathelwanayo. Ngenxa ukuthuthukiswa ngokushesha isayensi namuhla, lesi sifo ingelapheka emasontweni ambalwa. Nokho, amafomu eziphambili ngokuvamile imbangela yokufa. Sifaneleka ikakhulu ngenxa okusezingeni eliphezulu lokufa ka neurosyphilis.

Lesi sifo ukuzisho aphila kunoma iyiphi inkathi ukutheleleka syphilitic. Sifo kusekelwe imiphumela izindlela serological ucwaningo kanye ukubonakaliswa emtholampilo. Ngoba impatho kwamaphilisi evame ukusetshenziswa mincane-bohlu. Namuhla isifo neurosyphilis kwenzeka kakhulu kancane njalo kuka kule minyaka eyikhulu edlule. Lokhu kungenxa ngcono ikhwalithi izindlela zokuxilonga, izivivinyo zokuvimbela sabantu, ukwelapha ekuqaleni.

Ziyini izimbangela eziyinhloko zalokhu ukutheleleka

Lwegciwane neurosyphilis - ukuphaphatheka treponema igciwane. Ukutheleleka kumuntu ogulayo kwenzeka ngqo. Ngokuvamile, lokhu kwenzeka ngokusebenzisa ubuhlobo bobulili ngaphandle kokuzivikela. Lwegciwane ingena emzimbeni womuntu ngokusebenzisa unezilonda nolwelwesi lwamafinyila noma isikhumba. Lesifo ke zibhebhetheka kanye egazini.

Umzimba iphendula amagciwane angaphandle ngu ukukhiqizwa omzimba. Ngokunciphisa kusivimbeli gazi ebuchosheni ukuphaphatheka treponema busuka isimiso sezinzwa. Ngakho kancane kancane neurosyphilis.

Izimbangela lesi sifo futhi bangase ukugqoka nonspecific. Kutfutfukiswa isifo ukwelashwa imisiwe ikhuthaza amafomu ngaphambili lesi sifo, ukucindezeleka ngokomzwelo, amasosha omzimba encishisiwe, ukulimala ekhanda, yokukhathala kwengqondo.

Izindlela eziyinhloko ukutheleleka:

1. Ngokocansi. Kuyinto ifomu evamile yokudlulisela. Lwegciwane lingena nolwelwesi lwamafinyila kanye microdamages esikhumbeni. Uhlobo ngocansi ngokuvamile akwenzi inendima ekhethekile. Ukusetshenziswa isithiyo zokuvimbela inzalo (ikhondomu) kunciphisa ingozi yamagciwane, kodwa akusenzi ke zero.
2. Ngokumpompela Igazi (ukumpontshelwa igazi, manipulations amazinyo).
3. ZaseNdlunkulu. Ukuze ekuthelelekeni kuze kwansuku kudingeka ngokuseduze kakhulu umuntu ogulayo. It is hhayi ngaphandle ukudluliswa nge amathawula, izinto zasekhaya ezivamile, ngensingo noma isixubho.
4. Transplacental (umama okudlulisa ngqo i-fetus).
5. Professional. Okokuqala, kumayelana bezempilo abangekho contact njalo lomzimba (igazi, isidoda, ngamathe). Ukutheleleka kungenzeka zokubelethisa, ukungenelela kuhlinzwa, kwesidumbu.

Singalokothi sithintane no-umuntu itheleleke nge neurosyphilis, njalo uthwala usongo.

emitholampilo isithombe

Izimpawu neurosyphilis kungenziwa liphinyiselwe noma kusulwe, lapho lesi sifo ngendlela efanele usaqala yentuthuko. Ezinye izimpawu ezivamile isici isifo, odokotela kuchasiselwe ikhanda yansukuzonke, ukukhathala, ukungabi namizwa nasemilenzeni.

Ochwepheshe ukuhlukanisa ekuseni, okufana sekwephuzile futhi azalwa naso lesi sifo. Okokuqala ithuthukiswe iminyaka eminingana ngemva kokuzalwa ukutheleleka. Kungenjalo-ke kubizwa ngokuthi mesenchymal ziye ngokuyinhloko abathintekayo kulo sokugembula inqubo izitsha kanye nolwelwesi ingqondo. ifomu Late zokugula kuzibonakalisa cishe eminyakeni emihlanu kusukela Ukungena Treponema pallidum emzimbeni. It kuhambisana lesion of amangqamuzana ezinzwa yemisipha. neurosyphilis azalwa naso eba ngenxa yokudlulisela transplacental ukutheleleka kusuka kumama kuya fetus obonakalayo phakathi nezinyanga zokuqala zokuphila.

I neurosyphilis ekuseni

Le ndlela lesi sifo ngokuvamile eba phakathi neminyaka engu-2-5 ngemva Ukungena ukutheleleka emzimbeni. Lesi simo sihambisana lesion we ulwelwesi ubuchopho futhi imithambo yegazi. zako ezisemqoka ezisetshenzisiwe meningitis syphilitic, a ugcunsula kanye neurosyphilis esicashile. Izimpawu kanye izimpawu nobuntu ifomu ngalinye, cabanga ngemininingwane eyengeziwe.

1. Asymptomatic (esicashile) neurosyphilis kungenzeka ebizwa nge- "okungahleliwe" thola. Kulesi simo, izimpawu nobuntu kungukuthi waphawula, futhi uphethwe kungenziwa esisungulwe kuphela ushintsho ukubunjwa yotshwala.
2. Syphilitic meningitis uvame kutholakala nentsha. Phakathi izimpawu zokuqala bungabonakala isicanucanu nokuhlanza, izinhlungu zekhanda ezinamandla. I lokushisa lomzimba liyaphuma kakhulu kuyaqabukela. Ukuzibandakanya Kunokwenzeka inqubo zokucabanga okubangelwa isifo izinzwa cranial kubonakala ongaboni kahle kanye nokuthuthukiswa sensorineural ubuthulu.
3. A ugcunsula libhekene kahle kwegazi ebuchosheni. zokugula Clinical wabonakaliswa thuthuva sezinzwa, kukhuphuke ikhaliphe, kwehle ukunakwa inkumbulo ukungakhuli. Ukungabi ukwelashwa okufika ngesikhathi kungaholela unhlangothi ischemic. Ngokuvamile landulelwa zekhanda ezinamandla, ubuthongo ukungakhuli, kungenzeka nokuquleka.

neurosyphilis ngasekupheleni

Lokhu zokugula naye ehlukene ku ngezindlela ezihlukahlukene:

• ukukhubazeka Progressive.
• Tabes dorsalis.
• Gummy neurosyphilis.
• Yoma we emsipheni optic.
• neurosyphilis Meningovascular (izimpawu efana ifomu ekuqaleni kwalesi sifo).

Uma kuziwa ukukhubazeka lesichubekako, ukubandakanya meningoencephalitis ezingamahlalakhona. Wayevame eba emva kweminyaka 5-15 emva kokutheleleka nge ugcunsula. Isizathu esikhulu salokhu uhlobo lesi sifo - ukuphaphatheka treponemes Ukungena ku amangqamuzana obuchopho nokubhujiswa kwabo okwalandela. Ekuqaleni, iziguli kutholwa izinguquko womsebenzi ephakeme kwemizwa (ukuwohloka ukunakwa inkumbulo, ukucasuka). Njengoba ukuqhubeka kwesifo abazihlanganisa zengqondo (ukucindezeleka, okuyize, ukusangana). Phakathi kungenzeka izimpawu zokungasebenzi kahle kwemizwa waphawula eliqhaqhazelayo ulimi, dysarthria futhi ushintsho ngesandla. Lesi sifo eba ngokushesha futhi ezinyangeni ezimbalwa liyabulala.

Uma sithinta impande amaphiko nezintambo umgogodla, odokotela bathi tabes dorsalis. zokugula Clinical kuzibonakalisa ngesimo ukulahlekelwa iqakala ikhaliphe, ukungazinzi ngokwezomnotho kule sikhundla Romberg. Ngenxa yalokho zokushintsha Gait komuntu. Kungenzeka kwavela optic nerve yoma. Esinye isifo isici iyona izilonda trophic.

Yoma ka emsipheni optic , kwezinye izimo, uba ifomu ezimele lesi sifo njengoba neurosyphilis. Imiphumela sifo iyehlisa izinga lempilo. I kokuqala inqubo sokugembula kuthinta nelihlo elilodwa, kodwa ngemva kwesikhashana kuba zamazwe amabili. Ancishisiwe acuity ezibukwayo. In the ukungabikho ukwelashwa esifike ngesikhathi asathuthuka ngobumpumputhe.

Gummy neurosyphilis. Gummi kukhona zokwakheka oyindilinga okuyinto akhiwa ngenxa kwamathambo okubangelwa yi-treponema. Ingathinta asebuchosheni nomgogodla, ukugxisha izinzwa. zokugula Clinical livezwa ukukhubazeka yezingalo nemilenze neziyaluyalu okhalo.

neurosyphilis azalwa naso

Le ndlela isifo sitholakale kakhulu kuyaqabukela. Phakathi nenkathi yokukhulelwa, owesifazane okhulelwe ngokuphindaphindiwe novivinyo ukuhlonza izifo. Uma ukutheleleka intrauterine eyenzekile, kulula kakhulu ukuba aqaphele. Isithombe emitholampilo libhekene izimpawu ezifanayo njengoba ukuthi iziguli omdala, ngaphandle tabes dorsalis.

ifomu azalwa naso lesi sifo inezimpawu ehlukile. Lokhu okuthiwa iphimbo kanye Hutchinson triad: ubuthulu, keratitis kanye deformation we amazinyo engenhla. ukwelashwa esifike ngesikhathi ungayeka inqubo ukutheleleka, kodwa izimpawu zokungasebenzi kahle kwemizwa iqhubeka kukho konke ukuphila.

ukuxilongwa neurosyphilis

Kuyini neurosyphilis, siyatshelwa. Kanjani ukuqinisekisa sifo? uphethwe esichazayo kungenziwa okusekelwe criteria ezintathu eziyinhloko: isici isithombe yomtholampilo, imiphumela ngoba ugcunsula, ekuboneni izinguquko ukubunjwa cerebrospinal fluid. ukuhlolwa lolwenetisako isimo lesiguli isebenza kuphela emva luhlolo zezinzwa.

Ngokuphathelene ukuhlolwa laboratory, yenziwa ngokucophelela. Kwezinye izimo, ukuhlolwa ukuphindaphinda. Ilabhorethri kakhulu ulwazi izindlela zokuxilonga zihlanganisa RPR-ukuhlaziywa RIBT, Rif, futhi ukuhlonza ejenti ezithathelwanayo ngo okuqukethwe isikhumba abathintekayo.

In the ukungabikho izimpawu liphinyiselwe wenziwa lumbar wokubhoboza. Neurosyphilis e CSF show amazinga amaprotheni iyokhushulwa, kanye ejenti causative yesifo - ukuphaphatheka treponemu.

MRI kanye CT scan emgogodleni ezinqunyiwe zonke iziguli nge neurosyphilis okusolwayo. Sifo ngu apparatuses ekhethekile lembula yoma iphimbo kanye nobuchopho izidakamizwa.

Indlela ukunqoba neurosyphilis?

Ukwelashwa amafomu ekuqaleni kwalesi sifo kusekelwe yokwelapha nolaka antibiotic. Ngenxa yale njongo, amalungiselelo penicillin futhi cephalosporin chungechunge. Ngokuvamile, ayikho indlela yokuyelapha eziyinkimbinkimbi futhi kuhilela ukusetshenziswa imithi amaningi ngesikhathi esifanayo. Isikimu evamile: "penicillin", "Probenecid", "Ceftriaxone". Yonke imithi iphathwa ngemithambo yegazi. Imijovo "penicillin" futhi wenze umsele umgogodla. Inkambo yokwelashwa kuvame ukuthatha amasonto amabili. Ngemva kwalokho, isiguli asitholayo ukuphinda luhlolo, lapho ungakwazi ahlulele imiphumela yokuthi ukuthi kungenzeka ukunqoba neurosyphilis. Ukwelashwa yelule uma cerebrospinal umbukiso uketshezi ukuphaphatheka treponemu.

Ngosuku lokuqala yokwelapha izidakamizwa zingase zibe zimbi izimpawu zokungasebenzi kahle kwemizwa (uphethwe yikhanda, ukunyuka kwezinga lokushisa, tachycardia). Ezimweni ezinjalo, impatho is kwahambisana by izidakamizwa eqeda ukuvuvukala kanye corticosteroids.

Ukuze ulwe amafomu sekwedlule neurosyphilis wasebenzisa izidakamizwa nge-arsenic ne-bismuth libhekene ubuthi okusezingeni eliphezulu.

Isibikezelo nemiphumela

amafomu Sakudala neurosyphilis ukuphendula kahle ekwelashweni, alulame ngokugcwele kungenzeka. Kwezinye izimo, lalilokhu okuthiwa imiphumela asalile ngesimo paresis kanye dysarthria ukuthi kungabangela ukukhubazeka.

amafomu kwesikhathi zokugula kabi yokwelapha wezokwelapha. izimpawu zokungasebenzi kahle kwemizwa bavame ukuhlala nesiguli ukuphila.

Progressive ukukhubazeka edlule eminyakeni embalwa kuholele umphumela ebulalayo. Namuhla, nokusetshenziswa kwamaphilisi penicillin akuzange kusize ivumela nokunciphisa ukubonakaliswa izimpawu kanye neurosyphilis kancane.

Photo iziguli nale Ihlahlubo emva kokwelashwa izifundo asivumela ukuba baqonde zokugula usongo kuletha emzimbeni. Yingakho wonke umuntu azi ukuthi angasilawula kanjani ukuvimbela lesi sifo.

izinyathelo

Ukuvimbela ukutheleleka, odokotela batusa ukulahla ubuhlobo bobulili engalawuliwe. Kuyinto ukunakekela okukhethekile inhlanzeko yomuntu siqu. Abantu abatheleleke nge-Treponema pallidum, nsuku saziso kufanele ibhekane luhlolo ukuzivikela ngokuphendukela isazi sezinzwa.

Kuyini neurosyphilis? Lesi isifo esiyingozi libhekene CNS. In the ukungabikho ukwelashwa esifike ngesikhathi amathuba yezinkinga ezisongela ukuphila, okuyinto ngqo kuthinte izinga lokuphila, futhi ngezinye izikhathi kubangele ukufa. Ngakho-ke, akufanele sidebeselele nokuvimbela izifo, futhi emva kokutheleleka ngokushesha afune usizo lwezokwelapha.