Non-utshwala isifo okunamafutha isibindi (NAFLD): izimbangela, izimpawu, izimpawu kanye nokwelashwa

Non-utshwala okunamafutha isibindi isifo - ukugula kuhambisana ekuqongeleleni lipid amaconsi ku hepatocytes. inqubo enjalo ithinta ukusebenza emzimbeni futhi kungaholela yezinkinga eziyingozi. Ngeshwa, lesi sithombe sokucindezeleka ngokuvamile usongene, ngakho-ke lesi sifo sitholakale umuntu, njengoba umthetho, kakade wokwenziwa kweengaba zokugcina ukuthuthukiswa.

Kusukela zokugula wandile, abantu abaningi ukubuza imibuzo ngalokho kuyinto non-utshwala steatosis kwesibindi. Izimpawu kanye nokwelashwa, kubangela kanye nezinkinga - kuba amaphuzu kubalulekile ukucabangela.

Siyini isifo? Incazelo emfushane etiology futhi

NAFLD, non-utshwala isifo okunamafutha isibindi - a zokugula evame kakhulu ukuthi libhekene ekuqongeleleni kumaseli isibindi (hepatocytes) lipids. Njengoba amaconsi amafutha kuthiwa imali ngaphakathi amaseli bese esikhaleni extracellular, lo ukungasebenzi waphawula seziPhathimandla. isifo kungelashwa kuholela yezinkinga eziyingozi, okwandisa ingozi senhliziyo, isifo sokusha noma abulalayo isimila kumiswa esibindini.

Non-utshwala okunamafutha isibindi isifo - inkinga besikhathi sethu. Ngokocwaningo olwenziwa ukuvama mayelana 25% (kwamanye amazwe futhi kufika ku-50%). Nokho, izibalo kungaba uyibize ngokuthi olunembile, eqinisweni ukuxilonga ukugula ngesikhathi kuyaqabukela kungenzeka. By the way, bathambekele ke, kokubili amadoda nabesifazane, ngisho nezingane imbala. Ikakhulu ehlaselwe isifo emazweni athuthukile, okuyinto lihlotshaniswa ehhovisi, indlela fixed wokuphila, ukucindezeleka njalo kanye nokungondleki.

Ziyini izimbangela eziyinhloko zalokhu yesifo amafutha

Umbuzo othi kungani futhi kanjani ukuthuthukisa non-utshwala isifo okunamafutha isibindi, wenziwa namanje wafunda e izikhungo eziningi ucwaningo. Kodwa eminyakeni embalwa edlule, ososayensi baye bakwazi ukukhomba izici eziningana ingozi:

• Ukhuluphele (iningi iziguli nale Ihlahlubo kukhona okhuluphele).
• Ngakolunye uhlangothi, steatosis angagcina ku isizinda okusheshayo kwesisindo, ngoba lesi simanga kuhambisana ushintsho amazinga fat umzimba, futhi ama-fatty acid.
• Izinto ezibangela isifo sikashukela, ikakhulukazi yohlobo yesibili.
• Ingozi ekhulile yemiphumela ekuthuthukiseni lesi sifo kubantu abangu nge nomfutho wegazi ophezulu ezingamahlalakhona.
• NAFLD kungase kuvele amazinga aphezulu of triglyceride futhi cholesterol egazini.
• Yingozi ukusetshenziswa kunemithi noma amaphilisi owaphuzayo, ikakhulukazi ama-antibiotic ejenti hormone (zokuvimbela inzalo amaphilisi, glucocorticoids).
• Izinto eziyingozi ezingabangela i zihlanganisa ukudla okungenamsoco, ikakhulukazi uma Ukudla iqukethe izitsha abacebile carbohydrate ezilwane.
• Lesi sifo ikhulela wokugaya ukudla izifo pheshana, kuhlanganise goiter, izilonda emathunjini umshini, pancreatitis, nokwenziwa kahle kwezakhi ngasogangeni emathunjini.
• izingozi Ezinye izici zifaka sifo, isifo samaphaphu, psoriasis, lipodystrophy, izifo oncologic, izinkinga zenhliziyo, porphyria, ukuvuvukala ezinzima, ekuqongeleleni esiningi radicals khulula, zezinzwa izicubu isifo.

Non-utshwala isifo okunamafutha isibindi: ngezigaba komqondo nezinga lokukhula kwengane

Kunezindlela eziningana ukuze uhlukanise sifo. Kodwa odokotela abaningi sinake indawo inqubo. Kuye lapho ekuqongeleleni lipid amaconsi isehlane ebalulekile eqonda elisetshenziswa eqonda, ehlasela umzimba nomumo zonal gepatoza.

Non-utshwala isifo okunamafutha isibindi eba ngezigaba ezine:

• Fatty isibindi lapho kukhona ukunqwabelana esiningi lipid amaconsi ku hepatocytes nesikhala intercellular. Kuthiwa iziguli eziningi, lesi simanga aliholeli umonakalo omkhulu isibindi, kodwa khona omubi ezithinta izici isifo bathuthele esigabeni esilandelayo sokuthuthuka.
• steatohepatitis Nonalcoholic, lapho ekuqongeleleni fat kuhambisana ukuvuvukala.
• Fibrosis kuyimiphumela a ukuvuvukala eside. amaseli Functional isibindi kancane indawo yizinto zezinzwa. Amanxeba akhiwa, ezithinta ukusebenza emzimbeni.
• Isifo sokusha - esigabeni sokugcina ukuthuthukiswa cystic, lapho iningi evamile izicubu isibindi nezibazi ukufaka endaweni. isakhiwo iphazamiseke futhi umzimba ukusebenza, okuvame ukuholela esingamahlalakhona hepatic.

Yiziphi izimpawu ahambisana umkhuhlane?

Abantu abaningi nakudzingeka ukuxilongwa "non-utshwala isibindi steatosis." Izimpawu kanye nokwelashwa - izindaba ozithandayo iziguli eziningi. Njengoba sekushiwo, isithombe emitholampilo ye isifo nivame. Ngokuvamile izicubu ukukhuluphala isibindi akuyona ephelezelwa iziyaluyalu ezinzima, okuyinto nzima kakhulu uphethwe ngesikhathi esifanele ngoba iziguli nje musa ukufuna usizo.

Ziyini izimpawu ephelezelwa non-utshwala isifo okunamafutha isibindi? Izimpawu zesifo zihlanganisa:

• Ngenxa ukushayisana kwesibindi, iziguli kaningi esekhala iziyaluyalu wokugaya ukudla, ikakhulukazi, isicanucanu futhi ukusinda esiswini, okuyinto eyenzeka ngemva kokudla, izinkinga ne kwesitulo.
• Izibonakaliso ingase ihlanganise ukukhathala, ukuphathwa ikhanda yansukuzonke, ubuthakathaka kakhulu.
• Ezigabeni kamuva yokwanda ubukhulu kwesibindi kanye ubende. Iziguli esekhala ukusinda kanye nobuhlungu hypochondrium kwesokudla.
• Cishe 40% eziguli kungabonakala nasemkhakheni hyperpigmentation kwesikhumba entanyeni e emakhwapheni.
• Mhlawumbe ukubukeka spider emithanjeni (osuke usuvulekile capillary igridi) ku izintende.
• Ukuvuvukala uvame ukuhambisana yellowness we nesikhumba noma namehlo.

isifo Adipose ezinganeni

Ngeshwa, non-utshwala isifo okunamafutha isibindi ngokuvamile kutholakala izingane nentsha. Ngaphezu kwalokho, ngibheke phambili ezinsukwini ezimbalwa ezidlule, inamba yezimo ezinjalo ikhuphuke kakhulu, ngenxa ukwanda lokukhuluphala iziguli engamahlongandlebe.

Imiphumela yaloku kuhlola okungenhla Proper kubalulekile. Yingakho ngesikhathi nokuhlolwa odokotela esikoleni isimiso, odokotela ukukala kwemigomo umzimba wengane, ukulinganisa umfutho wegazi, hlola izinga le-triglyceride futhi Esilula. Lezi zinqubo enze kube nokwenzeka ukuba ukuxilonga izifo ngesikhathi. Non-utshwala okunamafutha isifo sesibindi esingelapheki kubantu abangamaphesenti izingane zingase zingafuni zidinga ukwelashwa ezinye ethize (ikakhulukazi uma kutholwa ukuthi isheshe itholakale). Ukulungiswa lokudla ukudla okufanele nokuvivinya umzimba njalo ibe nomthelela ekubeni ukuzinza kwesibindi.

izinyathelo kwesifo: Laboratory Ukuhlolwa

Uma usola ukuthi lokhu zokugula olwenziwa ezikhungweni zocwaningo amasampuli igazi esigulini. Lapho eseyinsizwa efundela ezomthetho Imiphumela yokuhlolwa kufanele sinake izinkomba ezilandelayo:

• Iziguli waphawula ukwanda enzyme isibindi. Ukwandisa ngokulinganisela, mayelana 3 - 5 izikhathi.
• Kukhona kungukuphula carbohydrate umzimba - iziguli kahle glucose ukubekezelelana, okuhambelana izimpawu uhlobo II sikashukela.
• Esinye isici - the dyslipidemia okuyinto libhekene nenkinga yezinga anda cholesterol ne-triglyceride egazini.
• Ukwephula amaprotheni umzimba futhi ukwanda bilirubin siyenzeka kuphela ezimweni eziphambili.

luhlolo Instrumental isiguli

Eqhubeka olwenziwa ukuhlolwa eyengeziwe, ikakhulukazi, ultrasound luhlolo isibindi futhi izitho besisu. Uchwepheshe phakathi naleyo nqubo ungase uphawule izingxenye ezifakwa lipid, futhi echogenicity ngcono. Phela, US kuyinto ekahle sitholakele ngokukhukhumala kwentamo okunamafutha isifo.

Ngaphezu kwalokho olwenziwa resonance kazibuthe kanye computed tomography. Lezi zinqubo uvumele umbono ophelele isimo lesiguli nezinga ukuqhubekela phambili kwesifo. Phela, usebenzisa tomography lula kakhulu ukuxilonga foci endawo okunamafutha isibindi.

Ngezinye izikhathi kudingeka ube biopsy isibindi. Laboratory Ukuhlola izithombe kwezicubu kusiza ukuthola ukuthi ngabe kukhona ukuvuvukala, noma lusatshalaliswe kakhulu cystic lokho Izibikezelo iziguli. Ngeshwa, le nqubo kuba kubenzima futhi enezinto eziningi izinkinga ngemva kokuhlinzwa, ngakho ukuchitha kuphela ezimweni ezimbi kakhulu.

imithi ye gepatoza nonalcoholic

Non-utshwala isifo okunamafutha isibindi, naphezu ukugeleza kancane, kuyingozi, futhi ngenxa yalokho sidinga ukwelashwa ngokushesha. Yiqiniso, isikimu ukwelashwa yenziwa ngamunye, njengoba kuncike ezintweni eziningi.

Ngokuvamile, kuqala elibekelwe seziguli ezithola hepatic kanye Antioxidants, ngokukhethekile, amalungiselelo equkethe betaine, tocopherol acetate, silibinin. La mathuluzi ukuvikela amaseli hepatic ekulimaleni futhi kancane ukuthuthukiswa isifo. Ephambi kwezinduna insulin e isiguli usebenzisa izidakamizwa ukuthi ukwandisa insulini ukuzwela receptor. Ikakhulukazi, imiphumela emihle kubonakala nge thiazolidinediones futhi biguanide. Uma kukhona ukwephulwa ezibucayi lipid umzimba asetshenziswa izidakamizwa lipid-ukwehlisa.

Non-utshwala isifo okunamafutha isibindi: izincomo iziguli

Njengoba ezikhathini eziningi sifo lihlotshaniswa ukukhuluphala neziyaluyalu umzimba, isiguli Kunconywa ukuba bagcine Ukudla ilungile futhi ulahlekelwe isisindo. Asikwazi ukuvumela okusheshayo kwesisindo - konke okufanele kwenziwe kancane kancane.

Ngokuphathelene nokudla ke udinga kuqala ukuqala kancane ukunciphisa nsuku zonke caloric ukubaluleka ukudla. Fat ekudleni nsuku zonke kumele singeqi 30%. Kuyadingeka ukuba ngakususi imikhiqizo ukwandisa cholesterol, ukulahla ukudla okuthosiwe nokudla utshwala. Imenyu nsuku ukufaka kudla kunothile fibre, vitamin E kanye polyunsaturated okunamafutha acid.

Ingxenye yokuyelapha nokuvivinya umzimba. Kufanele uqale nge umsebenzi ukulawuleka (ngisho nokuhamba) 30 - 40 imizuzu 3 - 4 izikhathi ngesonto, kancane kancane zandise izinto umfutho kanye nesikhathi sokuqeqeshwa.

Ingabe kungenzeka ukwelapha izindlela zabantu?

Imithi yendabuko inikeza eziningi amathuluzi angakusiza ngcono ukusebenza sesibindi ukuhlukana emzimbeni ubuthi. Ngokwesibonelo, kutuswa ukuba uhlanganise ezomile amahlamvu ukhova nezinyosi isilinganiso 3: 1. Thatha isipuni esigcwele ezinkulu phakathi ukudla 2 - 4 izikhathi ngosuku. Umuthi asifanele amanzi okuphuza, futhi-ke, ukudla imizuzu engu-40 ngemva ukungenisa.

nomthelela omuhle isimo decoction kwesibindi oat okusanhlamvu. Njengoba kubalulekile ukubuyisela microflora esiguli, kutuswa ukuba udle kakhulu ngendlela you fantshi imikhiqizo yobisi isibilile. Kufanele kuqondwe ukuthi self at gepatoze isibindi kungaba yingozi. Nganoma iyiphi indlela ingasetshenziswa kuphela nge kwemvume udokotela ukuba khona.