Pseudomonas aeruginosa: ukwelashwa kanye ikakhulukazi

Pseudomonas aeruginosa noma Pseudomonas aeruginosa - ezithathekayo Gram libhekisela ezingosomathuba. Emvelweni, lusakazwe kabanzi, ehlala kuwo umhlabatsi nemanti, izitshalo, e pheshana emathunjini e kokubili ezilwaneni. Kuyinto ezihambayo iningi micro-umzimba ukuthi kungabonakala nasemkhakheni amasampula amanzi athathwa ezivela emithonjeni yemvelo mhlawumbe.

Yini ihlukile kwezinye amagciwane ngentuba, kungani 'uzekwayo kangaka odokotela nososayensi bakhangwa Pseudomonas aeruginosa? Ukwelashwa nokuvikelwa izinqubo sokugembula odalwe lolu silwanyana, kunzima kakhulu, Wand kuyinto multiresistant nemithi. Kanye sofuba Mycobacterium nasezinhluphekweni zakulezi ezithile staphylococci, lingelikaJehova amabhaktheriya ukumelana kakhulu chemotherapeutic izidakamizwa atholakalayo namuhla. Kodwa ngisho kulolu hlu, ngokuvamile kudinga indawo ehamba phambili.

Lokhu kungenxa khona biofilm, okuyinto unendima zokuzivikela, kanye isithiyo okuyinto adalwe elingaphandle lipopolysaccharide ulwelwesi. Futhi kukhona zamagciwane okuyinto anenkani cishe zonke ezaziwayo namuhla.

Nokho, Pseudomonas aeruginosa, amalungiselelo imithi okuyinto kuyinselele, nozwelo phenol (esibulalini 2% isixazululo), 3% i-hydrogen peroxide kanye chloramine (0.5% isixazululo). In imvelo, ikakhulukazi emanzini futhi umoya zinomswakama igciwane uyakwazi hhayi kuphela iqhubeka isikhathi eside, kodwa futhi zanda. Eliphezulu ukuthuthukiswa yayo ubhekwa 37 ° C lokushisa, kodwa futhi ngaso 42 ° C imbewu eletha uyakwazi ezikhulayo.

Pseudomonas aeruginosa: Izimpawu

A indima ebalulekile kakhulu ukuthuthukiswa amagciwane izifo nosocomial, basengozini ngokuya lengculaza nokucwila, izindlu zangasese, ompompi izibambo, izinto ezimanzi (amathawula, isibonelo). izilonda Local ngokuvamile zenzeka endaweni ukusha kanye ezivuzayo nasezinkingeni ezilandela ngemva kokuhlinzwa, ukusikeka kanye amanxeba. Ngokuvamile ukuthola induku nge otitis, pyoderma, dermatitis. Ngenxa yalokho yokulimala noma ukuhlinzwa igciwane kungabangela izifo esweni, kanye ngomgudu womchamo (ngokuvamile besebenzisa ipayipi).

Ukuze izinqubo sina ukuvuvukala, okungase kusolwe Pseudomonas aeruginosa, zihlanganisa endocarditis (umonakalo ka valve inhliziyo), i-pneumonia, ubuchopho ithumba, meningitis, i-shock syndrome, emalungeni. Ngokuvamile, ukugula noma izifo zibangelwa lokhu induku, kaningi kuholela bacteremia - ukutheleleka wonke umzimba ngokuqondene kwema- agent ezithathelwanayo egazini.

Isici nobuntu le-bacterium oqinile Ukukhetha endo- futhi exotoxins, hemolysin, cytotoxins, umsebenzi okusezingeni eliphezulu proteolytic, synthesis hyaluronidase, ikhono synthesize kwakwakhe krahmalopodobnogo njengoba isikhwehlela, okwandisa impahla yayo ingcina, kanye eziningi zemibala. Izilonda kubangelwa wathi silwanyana zenzeka ne izimpawu ezinamandla zokudakwa, izinga lokushisa eliphakeme. Ikakhulukazi, Pseudomonas inyumoniya omsakazo njalo uyagijima kanzima, ukubukela ekuseni iziqongo imfiva, iphika cyanosis. I okusezingeni eliphezulu lokufa (50-60%) laligujwa at meningitis, uma yokutakula esiguli, ophikelelayo imihlola asalile waphawula njengoba iziyaluyalu okwedlulele zezinzwa.

aeruginosa Pseudomonas: ukwelashwa

Okokuqala udinga izindlela laboratory ukunquma nozwela lwegciwane emuthini. Ukwelashwa nokuvikelwa Pseudomonas aeruginosa, njengoba umthetho, kudinga ukuqashwa kukaNksz eziningana (okungenani amabili) kwama-antibiotic. Ngo-acute, ezisongela ukuphila ezimweni lapho isikhathi silinde imiphumela izitshalo hhayi antibiotic, avame amagciwane ebucayi, ukuba umthamo esiphezulu. Lezi zihlanganisa izidakamizwa penicillin akuzange kusize lesihlanu kanye isizukulwane lesithupha (amdinotsillin, pitratsillin, azlocillin). Ngokuvamile kukhona ngempumelelo futhi carbenicillin. Osetshenziswayo futhi cephalosporins - tsefzulodin, ceftazidime. Avame kuhlangene i aminoglycoside. Ngokuphumelelayo nokusetshenziswa emthanjeni of ciprofloxacin. Emva kokuthola zokutshala Imiphumela ukucacisa wesifunda yokwelapha.

Lapho yefilakisi, okungamahlalakhona, okwakumenza angenwe izifo kalula self-ephulukisa, okuyinto zibangelwa Pseudomonas aeruginosa, ukwelashwa ngaso sonke isikhathi kudingeka. Ezimweni eziningi kwanele nika omunye umuthi olwa namagciwane. Muva nje, ngokokuqala ekwelapheni Pseudomonas bacteriophage kabanzi ketshezi. Nokho, kufanele sikhumbule ukuthi kuleli cala kubalulekile ukunquma nozwela lwegciwane ukuba amalungiselelo begazi.