Umuthi 'papaverine "(isibhamu)

Nomuthi "papaverine" (imijovo) kuyinto antispasmodic, nemiphumela hypotensive. Umuthi uyakwazi zivimbela PDE (PDE), imbangela ekuqongeleleni ekamu (Adenozinmonosfata eyindilinga) ukwehlisa Ca2 +.

Kusho "Papaverine" (ukufakwa) ephumula futhi kunciphisa bushelelezi imisipha ithoni kwezitho zangaphakathi (genitourinary, wokugaya ukudla, zokuphefumula) nempahla. Isikali olwengeziwe singaluthola nangokufunda ukunciphisa excitability we senhliziyo esilimele futhi conduction kancane (intracardiac). Izidakamizwa "papaverine" (isibhamu) kunomphumela wavuma abusisa ngaso CNS. Ngemithamo ezinkulu ke unomthelela sine.

Ukuphumelela lomuthi waphawula emva kwemizuzu amabili kuya amane ngemva kokuphathwa. Isenzo zomuthi ingahlala kusuka amahora amane kuya kwayisithupha.

Kusho "papaverine" (imijovo) kuboniswa ngenxa spasm imisipha abushelelezi semithambo neuropathy (endarteriite), izitho ngaphakathi komgodi ongaphakathi kwamathumbu (colic kwezinso, nesifo spastic pilorospazme, cholecystitis), inhliziyo (angina ekwelashweni), izitsha ubuchopho (cerebral). Umuthi kuboniswa ngenxa premedication (belungiselela ukuhlinzwa) njengoba izidakamizwa osizayo.

Hhayi engabelwe ukufiphala hypersensitivity, AV block, kwasebekhulile, ukuhluleka kwezinso ezinzima, ebuntwaneni (sikhatsi lesingaba tinyanga letisitfupha).

Ngokulungiselela ngokucophelela isetshenziswa ezigulini eziye kwadingeka ukuhlukumezeka ikhanda, isimo ukushaqeka, nomsebenzi enganele indlala adrenal, Hyperplasia we wendlala indlala, i-hypothyroidism, tachycardia supraventricular.

Ukusetshenziswa kwalesi izidakamizwa Ingabangela arrhythmia ventricular, ukuqunjelwa, ukwehlisa umfutho wegazi, ukusabela iguliswa, ukozela, eosinophilia, kukhuphuke transaminase umsebenzi "isibindi".

Ngo ukweqisa izidakamizwa waphawula diplopia, somnolence, ubuthakathaka, ukwehla ingcindezi (igazi). ukwelashwa okunezimpawu kufanele isekele BP.

"Papaverine" imijovo. Yokusetshenziswa.

Phansi kwesikhumba, intramuscularly iqondiswa amabili kuya amane angu (1-2 ml isixazululo amaphesenti amabili), usuku, izikhathi ezimbili kuya kwemine. umjovo i-intravenous Kwenziwa kancane. Isikali - angu amabili.

Ukusebenzisa izidakamizwa "papaverine" (imijovo) kufanele sinikezwe kuphela ngaphansi kweso lwezokwelapha.

Phakathi ukwelashwa kubalulekile ukubeka eceleni yokuvuma ethanol.

Emtholampilo esungulwe ukuphepha izidakamizwa phakathi nokukhulelwa kanye lactation. Ukuqokwa is hhayi Kunconywa ngaphansi kwalezi zimo.

Lapho ukubhema ugwayi incipha vasodilating nomuthi.

Izidakamizwa "papaverine" uyakwazi ukunciphisa umphumela hypotensive ka methyldopa futhi levodopa kusebenta antiparkinsonian. Kube okhulisa izakhiwo antispasmodic zomuthi ngenkathi usebenzisa nge barbiturates. Hypotensive umphumela izindlela kungase kukhule lapho kuhlangene quinidine, reserpine, procainamide, tricyclic antidepressant.

Umuthi iyatholakala ngefomu ithebhulethi, ngesimo suppositories. Amakhandlela abe nomthelela wendawo. Bavame (suppository) ayesetshenziswa kwayo nezifo zabesifazane ukuze akhulule uthi spastic. Amakhandlela ezibhekwa izindlela ezinamandla kakhudlwana ukuze akhulule zibe kwezitho okhalo.

Ukusebenzisa izidakamizwa ezinganeni kufanele ziqondiswa uchwepheshe.

Ukuqokwa kufanele ukuvala amathuba khona Izimo.

Ukwemukelwa sefomu tablet ye izidakamizwa izingane kufanele ziqashwe nguchwepheshe.

Kusho "papaverine" kubhekwa izidakamizwa wandile okudambisa izinhlungu zibe. Njengoba kuboniswa umkhuba emtholampilo, imithi kahle ikubekezelele iziguli.