Umuthi 'Triftazin ": yokusetshenziswa, intengo, analogs, ukubuyekezwa. Overdose, imiphumela emibi, futhi ukuqedwa "triftazin"

Izidakamizwa "Triftazin" imfundo okuzokwenziwa wachaza ngokuningiliziwe kulesi sihloko, kubhekwa omunye ephumelela kunazo imithi antipsychotic. Ukusetshenziswa kwalesi izidakamizwa lihlotshaniswa ubuqili eziningi ngokuya umthamo kanye isikhathi yokwelapha.

Incazelo lokulungisela Ukwakheka

Ngokusho iqembu sokusebenzisana izidakamizwa "Triftazin 'kubhekisela esenzakalweni esiyisimangaliso izidakamizwa eqinile antipsychotic sibe nomthelela emelene emetic. The main isithako kuyinto kwakwakhe kusukela iqembu phenothiazines - trifluoperazine, okungase kuthinte hhayi kuphela isimiso sezinzwa esiyinhloko, kodwa futhi ezigabeni zalo neuropathy, ngaleyo ndlela, eqinisweni, has umphumela antiemetic.

A isixazululo lomjovo okucacile, uketshezi kungekho nto enemibala emihle, akukho iphunga eyinqaba futhi ukunambitheka. Tablets "Triftazin" babanjwa, camera okwesibhakabhaka, ekuqa- omhlophe noma cishe emhlophe.

Khipha ifomu, imigomo nemibandela isitoreji

Medicine "Triftazin" impendulo evela kodokotela mayelana nokuthi iziphi izinhlelo cishe njalo akhayo, etholakala amafomu amabili Isikali: njengoba isixazululo umjovo kanye amaphilisi. Okuqukethwe lomcebo asebenzayo ampule ngasinye isixazululo of 0.2% (2 mg e 1 ml isixazululo). I ampoules tihlelwe sebesemabhokisini 5, 10, noma 100 izingcezu ndawonye ekhethekile ampoule ummese kanye yokusetshenziswa zomuthi.

Ngo amaphilisi "Triftazin" ketshezi asebenzayo kuqukethwe imali 0,005% (0.5 mg). Agcwele e amabhamuza yizicucu 10, okuyinto yena, afakwe amakhadibhodi amabhokisi ne 4, 5 noma 10 izingcezu ngamunye. Futhi iyatholakala ngomthamo ifomu izigubhu ngengilazi amnyama noma plastic ezimhlophe opaque, equkethe amaphilisi 50 noma 100.

Impilo yabo bonke izinhlobo umthamo kuyinto engu-3. Gcina izibhebhe futhi isixazululo "Triftazin" yokusetshenziswa Kunconywa endaweni epholile ne komoya okuhle. Awukwazi ukuvumela ukuba amaphakheji kwemithi ukuqondisa elangeni noma uketshezi. it is hhayi Kunconywa ukuthatha izidakamizwa emva kosuku lokuphelelwa yisikhathi.

izakhiwo kwemithi "Triftazin" izidakamizwa

Ake sicabangele izakhiwo eziyisisekelo lesi sidakamizwa "Triftazin". Yokusetshenziswa (official) sinikeza ngolwazi olunemininingwane ngokuthi lo mshini wezenzo we asebenzayo izidakamizwa into la mangqamuzana ezinzwa asebuchosheni emsipheni vagus esiqeshini gastro-emathunjini. Ngokwesibonelo, lithi trifluoperazine PMD amabhlogo ama-receptor asebuchosheni D2 zemizwa cerebellum. Ngaphandle lokhu neuroleptic sikwazi ukunikeza alpha-adrenoceptor Ukuvinjwa umphumela, okungukuthi, umthelela esebenzayo ku blood pressure, ukwehlisa ke.

Nokho Trifluoperazin wafunda ngokujule ngokwanele ngokuya pharmacokinetics, wazi kahle ukuthi ngenkuthalo nakanjani plasma amaprotheni (okungenani u-80%). kwamazinyo elihlangana ezosetshenziswa metabolites njengoba ufundwa kancane. Excretion zomuthi kusukela umzimba kwenzeka ikakhulukazi nge izinso, ingxenye encane ketshezi asebenzayo futhi metabolites salo okukhipha ngokusebenzisa emathunjini (e Bile).

izinkomba

Njengoba imanuwali isenzo "Triftazin" ukulungiselela imfundo libabiza ngokuthi antipsychotic, zokugula nezifo eziningi okuyiwona kuzuzisa ukusebenzisa, kuhlanganisa ezihlukahlukene okuthile engqondweni. Phakathi kwabo - lokusangana, lengqondo thuthuva, ixhala ukwesaba (ongalawuleki ukwesaba esilawulayo). Ngaphandle kwezidakamizwa isetshenziselwa ukwelapha emesis ayibangelwa izifo emathunjini.

Kuphephe kangakanani sisuke sicabanga izindlela ukuthi zonke izigaba iziguli ingasetshenziswa "Triftazin"? Yokusetshenziswa, ochwepheshe wangempela ke lingahunyushwa baphetha ukuthi kubalulekile ukuthatha izidakamizwa kuphela emva inhlolovo esibanzi, njengoba nje iye eziningi nemiphumela emibi kanye contraindications. Naphezu kweqiniso lokuthi wakhulula izidakamizwa ngaphandle kadokotela, ukunquma wavuma akudingekile.

Izimo

Ngesikhathi amaphilisi kanye isixazululo "Triftazin" imijovo kukhona contraindications ukusetshenziswa ukuthini lokho ukungabi nakwenzeka kwento ukusetshenziswa kwazo. Phakathi kwabo zibizwa sezinzwa uhlelo ukucindezeleka futhi equlekile. Ngaphezu kwalokho, lesi sidakamizwa "imiyalelo Triftazin 'ukusetshenziswa is hhayi Kunconywa ukuthatha e izifo zenhliziyo, isibindi kanye nezinso, hematopoietic uhlelo. Nesigaba lesi sifo nokugasela ngamandla busebenze akusho badlala indima ebalulekile. Iqiniso lokuthi kukhona eziningana imiphumela yokwamukela amaphilisi kanye "Triftazin" isixazululo. Imiphumela engemihle, okuzoxoxwa kamuva, ngokwabo zinzima kakhulu, futhi khona comorbidities angase avuse nemiphumela ngisho kuyinkimbinkimbi nakakhulu ukuze isiguli.

It is ibuye Kunconywa hhayi ukusebenzisa ithuluzi nge umlando komzimba nezinto iyiphi ingxenye izidakamizwa.

Ukusebenzisa "Triftazin" ngesikhathi sokukhulelwa

I asebenzayo izidakamizwa imithi "Triftazin" (ukubuyekezwa odokotela aqukethe ngakho eziningi nemininingwane esekela) inomphumela omubi phezu embungwini. Ngakho hhayi Kunconywa ukuthatha izidakamizwa ngesikhathi sokukhulelwa. Iqiniso lokuthi esebenzayo izidakamizwa trifluoperazine ezitholakele kwezicubu fetus lokuhlala kuphakame kakhulu kunalokho ngemithamo zokwelapha. Lokho-ke kwenza abantu bakuphathe isethi ezibuthakathaka isisindo sengane, futhi kwandisa ingozi yokulimala ekwakhiweni ahlukahlukene ekukhuleni kwakhe.

Izidakamizwa "Triftazin" (analogs we ketshezi esebenzayo Kuyadingeka ukuba acabangele) is hhayi Kunconywa kanye lactating abesifazane njengoba izithako izidakamizwa ezitholakala ngobisi lwebele. Ngisho noma umama ngeke zibukele yini imiphumela emibi, ingane esikhathini esizayo ungase ubhekane nezinkinga ezifana tardive dyskinesia nokudideka.

side effects

Njengoba kushiwo ngaphambili, lesi sidakamizwa "Triftazin" kungabangela eziningi ukusabela ezingezinhle phezu ingxenye cishe zonke izinhlaka futhi izinhlelo. Ngokuyinhloko izidakamizwa esebenzayo kuthinta isimiso sezinzwa esiguli, okusho ukuthi share sengonyama amathuba okuba nemiphumela engemihle kwenzeka kuwo. Okokuqala, bafake ezinjengokungcoliswa Isakhiwo sazamazama, imisipha zibe entanyeni nolimi, kungani kungase egwinya (ukusabela extrapyramidal). Izimpawu ze-dyskinesia tardive zivela njengoba ngokuvamile kunjalo, ukuqwasha, akathisia, neziyaluyalu autonomic.

Okuvame kakhulu ukusabela ezingezinhle ezivela isimiso sezinzwa esiyinhloko kubangelwa edonsa "Triftazin" izimpendulo izidakamizwa libizwa ukozela, isiyezi kanye nokulahlekelwa nokucaca kombono. Ngokuvamile lezi zimpawu, kwenzeka kuzona ngokwazo ngosuku lokuqala ngemuva kokuqala ukwelashwa izidakamizwa.

Yini enye kungabangela isixazululo reception ngoba umjovo noma amaphilisi "Triftazin"? Imiphumela engemihle, ngokuvumelana ubufakazi iziguli nodokotela, ngokuvamile kuthinta isimiso sokugaya ukudla bungene. Lokhu kubonakala ifomu omlomo ezomile noma ukuzincisha. Futhi, kaningi kukhona izinkinga kanye ukusebenza evamile kwesibindi. Ngaphezu kwalokho, ukubukeka okungenzeka iguliswa ukuqubuka kwesikhumba, ukukhishwa amenorrhea, agranulocytosis.

Izixwayiso

Le ncwadi eshiwo ngenhla imiphumela emibi kungenziwa mitigated by ukwelashwa lingaze noma umthamo ukulungiswa. Khansela "triftazin" liyadingeka kuphela uma kukhona ukuphazamiseka sina ukuze isitho izinhlelo lesiguli. Ngakho, sicabanga amasu eziyisisekelo kanye nezindlela kulahlwa noma ukunciphisa ukusabela abangazidingi izidakamizwa.

Lapho ukundindizela noma ukuquleka ezimweni eziningi, ochwepheshe zithatha isinqumo ukunciphisa amazinga okukhishwa ezithathwe isiguli noma ukumisa okwesikhashana i-reception yakhe. Ezimweni ezimbi kakhulu kungase kudinge ngemithi antiparkinsonian, barbiturates noma caffeine izidakamizwa (administration ngomjovo).

Lapho izimpawu liphinyiselwe zokuqwasha noma motor disinhibition, ukuyaluza is hhayi Kunconywa ukwandisa umthamo sokuqala. Ngokuvamile ezinsukwini ezimbalwa umzimba uvuma ezinhlotsheni umuthi omusha, futhi kancane kancane izimpawu ezingezinhle zinyamalale. Kungenjalo, singadinga ngemithi "benzodiazepine" noma "Propanolol".

isimo esinjalo dyskinesia tardive, okukhulunywe ngaye phakathi emibi uma ethatha "Triftazin" izidakamizwa, ukubuyekezwa okuzokwenziwa echazwe lapha, ngokuvamile eba ngenxa ukusetshenziswa eside zomuthi noma ngokushesha ngemva kwalowo yokukhansela yayo. Ochwepheshe uqaphele ukuthi dyskinesia (tardive) ngokuvamile kutholakala iziguli esezikhulile.

Ezinye imiphumela emibi kubangelwa edonsa a nomuthi ingahambisani ne izenzo ezifana ukulawula izimoto kanye nezinqubo eziyinkimbinkimbi. Ngesikhathi sokwelashwa "triftazin" kangcono uyeke kubo.

Iziqondiso imithamo nezindlela sokulungiselela Ihora

Isikali kunqunywa nguchwepheshe ngesisekelo isiguli ngazinye, ngesimo sakhe khona izifo concomitant. umthamo ubuncane "Triftazin" izidakamizwa ngokuvamile iqondiswa ngokuhamba ukwelashwa. Tablets umyalelo siyalela ukuthatha 1-5 mg izikhathi 2 ngosuku (for iziguli omdala). Ezalandela amasonto amathathu, umthamo liyakhula kancane kancane futhi kushintshwe 45-60 mg ngosuku. Le mali kumelwe futhi ihlukaniswe izigaba ezintathu.

Ukuze ekwelapheni izingane Kuyinto evamile ukusebenzisa imithamo ezincane zomuthi. Ekuqaleni yokwelapha ningathathi ezingaphezu kwezingu-3 mg ngelanga (ngezigaba 3). Uma kudingekile, futhi ukungabi khona evelele komzimba nezimpawu umthamo senyuselwa 6.5 mg ngosuku.

Ukufakwa "Triftazin" kufanele sinikezwe intramuscularly ngezikhawu amahora hhayi ngaphezulu kuka-6. I umthamo wansuku zonke abadala nge obungu-10 mg. Izingane sikhombisa umthamo 1 mg ngelanga, ihlukaniswe ngemijovo emibili, ngezikhawu esikhathini esingekho ngaphansi kwamahora angu-12.

Thina ukuziqhakambisa yomfundi yokuthi ukuphathwa nale izidakamizwa, kungakhathaliseki ifomu Isikali kumele kwenziwe ngaphansi kokuqondisa kukadokotela. Nguye onquma ku izinguquko Isikali esinqumeni imithi "Triftazin". Overdose uma isetshenziswa kahle, kusho cishe akunakwenzeka. Ukusetshenziswa okungagunyaziwe izidakamizwa, noma ushintsho umthamo watusa ngendlela enkulu kungaholela nemiphumela engalindelekile.

izidakamizwa ekuhlanganyeleni

Yonke imithi bavame ukuba nihlanganyele. Amaphilisi kanye "Triftazin" umjovo kulokhu nabo bayajabula. Ngokuvamile, ochwepheshe acabangele izici eziningi ezithinta nekusebenta ukusetshenziswa kwalesi izidakamizwa. Ngakho, ukuthaka imithi equkethe ethanol (Syrups, isithako nomuthi kanye nokunye okufana nalokho), CNS depressants kungavundisa izakhiwo "triftazin", futhi zibulale izinqubo emishinini yokuphefumula.

Ngokuhlanganyela izidakamizwa okuyinto ukunciphisa blood pressure, ithebhulethi noma isixazululo "Triftazin" kufanele zifakwe kakhulu ngokucophelela ngangokunokwenzeka ekuthuthukiseni acute hypotension orthostatic.

Antacids namanxusa antiparkinsonian ibe neqhaza ukumuncwa elincane of esebenzayo izidakamizwa zithutha "Triftazin" kusukela ipheshana yesisu, futhi ngenxa yalokho, ukunciphisa ukuphumelela izidakamizwa.

Umphumela ongemuhle bubonakala nalapho babambisane isicelo izidakamizwa nge lithium nosawoti. Ngokolwazi wathola, inhlanganisela enjalo igcwele ukuthuthukiswa izimpawu evelele extrapyramidal futhi ngakhula Neurotoxic umphumela trifluoperazine.

Uphenyo imithi "Triftazin"

abaningi uzama ukuthola izibuyekezo mayelana ngaphambi kokuthi uqale ukuphuza umuthi. Medicine "Triftazin", nahlulele by okwashiwo izazi, kubhekwa omunye ephumelela kunazo. Ngesikhathi esifanayo, bona wazi ukuthi engalawuliwe ngokuthatha izidakamizwa angase abe nomthelela ongemuhle hhayi kuphela ngokomzimba kodwa esimweni sengqondo somuntu.

Kulabo iziguli abaye babonisa ukwamukela izidakamizwa, futhi livela ezimweni eziningi kuyindlela kuphela ukuphila okuvamile. Yiqiniso, akuyona ngaphandle kokuba nemiphumela engemihle. Kodwa, ngokusho izibalo, zonke izimpawu ezingemnandi zinyamalale kungakapheli esiphezulu amasonto amabili ngemuva Ukuqalwa yokwelapha.

Imibono ephathelene Triftazin eziguli "imithi elixutshwe. Omunye wabasiza ngempela, ngenkathi abanye kunzima ukubekezelela imiphumela emibi ukuze kwadingeka bayeke leli thuluzi. Isikhathi esining impela abathengi ukhombise ukubonakala ukukhathala, ukucobeka kanye ubuthakathaka jikelele. Ezimweni ezingavamile, iziguli yawela esimeni lapho bengafuni ukwenza ngisho ukunyakaza eziyisisekelo kakhulu.

Abesifazane, ngokungafani nabantu abangamagovu, livamile ukukhuluma ngazo ukwanda isisindo emzimbeni ngesikhatsi ukwelashwa nge "Triftazin". Ochwepheshe baphawula kutsi okuqondile phakathi lokhu yokwelapha izidakamizwa futhi akukho nzuzo isisindo. Bacabanga ukuthi lokhu kungenxa ukwehla umsebenzi motor iziguli ngokumelene isizinda ukulondolozwa yokudla wangaphambili.

Wayenethonya maqondana umphumela izidakamizwa, futhi odokotela kanye neziguli baye baqaphela ukuthi empeleni kusiza noma aqede zonke izimpawu zesifo ecashile.

Analogs futhi izindleko zomuthi

Ngakho, sahlola izimpikiswano ezinkulu ekusetshenzisweni "Triftazin" izidakamizwa. Kukhona unayo it akumiselelwa okulingana, noma okuthiwa analogs? Yiqiniso, le mithi inqwaba. Antipsychotics manje ukukhiqiza cishe zonke namakhamphani weenhlahla, futhi iningi izidakamizwa kuleli qembu ethulwa lahlotshaniswa "triftazin" (ie ukumhlangabeza ukubunjwa). Lezi zihlanganisa "Vespezin" izidakamizwa "trifluoperazine hydrochloride", "trifluoperazine hydrochloride", "fluazinam," "Ekvazin", "Stelazin", "Cyclodol" kanye nabanye abaningi.

Izindleko le mithi akuzona njalo efanayo. kumakhophi Foreign kaningi ibiza kakhudlwana, uma iqhathaniswa naso izidakamizwa "Triftazin", okwabangela inhlekelele okuyisilinganiso sabangu-ruble 50-70 iphakethe ngasinye (amaphilisi 50). Uma sicabanga ukuthi nokusetshenziswa leli thuluzi, ubude ukwelashwa, kungaba kubhekwe inani layo njengoba omunye izinzuzo main phezu analogs angaphandle.