Wokugoma HIV kuzokusiza ukwakha amasosha omzimba izinkomo

Izinkomo bangadlala indima ebaluleke kakhulu ekulweni ne-HIV. Uchungechunge lwemfundo ucwaningo, abacwaningi bathola ukuthi izinkomo unekhono ngokushesha namasosha igciwane, ezingasetshenziswa ukusiza ekukhiqizeni umjovo ukuze ulwe nesifo esibhubhisayo.

Izinga lwamasosha omzimba oluvame

Umsebenzi eyenziwa yi-US National Institutes of Health, luveza ukuthi izinkomo utheleleke nge-HIV antigen, waqala kokukhiqiza amasosha omzimba eyaziwa ngokuthi bNAb (ngobubanzi zokuyithena amasosha omzimba) ukuthi bophezela kuphela evulekile ebusweni antigen. Emva kwezinsuku 42 kuphela, ososayensi batholé ukuthi amasosha omzimba izinkomo singadambisa amaphesenti nesigqi ihlolwe we-HIV 20, futhi phakathi nezinsuku ezingu-381 inani lakhuphuka lafika ku amaphesenti angu-96.

"Le miphumela washaqeka ngempela kithi, - uthe uDkt Devin Soklt. - Baze kulukhuni kukukholwa loko, njengoba umzimba zabantu namasosha, sikhuluma iminyaka, kuthatha ezintathu kuya kweziyisihlanu. Lokhu kubalulekile ngempela ngoba umzimba wethu ngeke ngesikhathi esincane kangaka ukuba sibhekane ngokuphumelelayo lo msebenzi obalulekile. Ubani nje nempela owayeke wacabanga ukuthi inkomo uzokwenza neqhaza elikhulu ekulweni ne-HIV? ".

izici Eyingqayizivele omzimba izinkomo

Izinkomo abakwazi HIV ngendlela yemvelo, njengoba igciwane sokuba wezinkawu futhi kuhloswe, ukuhlasela amangqamuzana omuntu. Nokho, abacwaningi bebelokhu benesithakazelo ukwazi ukuthi umzimba izinkomo bayosabela kanjani lapho igciwane ngoba amasosha omzimba izinkomo inezici ahlukile, ngokososayensi, izimo zivuma akhiqiza amasosha omzimba enamandla ephendula ukutheleleka.

Abacwaningi injected antigen viral 117 amathole ukufunda impendulo umzimba. Nokho, ijubane impendulo kwesimiso somzimba sokuzivikela ezifweni kwezilwane ehlaselwa abacwaningi. Bavele baphethe ngokuthi ngoba isimiso sokugaya ukudla bungene izinkomo ezigcwele ama-bacterium inhlabamkhosi utshani, amasosha omzimba izilwane wathola ikhono ngokushesha akhiqiza amasosha omzimba ukugcina la magciwane ngaphansi kolawulo.

Ezimweni ezingavamile, abantu abathile bayakwazi ngokwemvelo ukukhiqiza amasosha omzimba afana, kodwa ngenxa yokuthi kuthatha isikhathi eside emva kokutheleleka, igciwane ekwazile liguquke futhi uzinqobe. Nokho, izinkomo bNAb ekhiqizwa phakathi namasonto ambalwa.

Inani ucwaningo olusha

"Okutholakele yethu Okwaphawuleka ngoba izifuyo, ngokusobala ukhiqiza amasotsha omzimba bNAb esikhathini esifushane yesikhathi. Ngokungafani amasosha omzimba womuntu izinkomo cishe uyoba izici eyingqayizivele futhi ube inzuzo phezu immunogens eziyinkimbinkimbi HIV ", - wachaza Dennis R. Burton, owayehola kulolu cwaningo.

Nakuba lokhu okwatholakala kubalulekile, abacwaningi ukuxwayisa ukuthi amasosha omzimba awukwazi ngqo zisebenzisa ekulweni ne-HIV kubantu. Nokho, lokhu kungaba isinyathelo esibalulekile ekukhiqizweni kwezinye iyahambisana umzimba omzimba womuntu, nakho zingaphendulwa zibe yizindawo yokuhlanganela wokugoma.