Yikuphi-analog "pregna" ukuyisebenzisa? Ukuqhathanisa ukuba efanayo "pregna"

"Pregnil" lisetshenziswa ekwelapheni anovulatory ukungazali kwabesifazane, kwesisu, usongo samoaborta, kanye elawulwa giperstimulirovaniya wesibeletho, lokungeniswa nge-ovulation, anda amazinga estrogen. Ukusetshenziswa Its ngempumelelo therapy esikhundleni isikimu lutein i-hormone endogenous ukuze sikhuthaze nokuvuthwa follicular.

Izinkomba ukuze isetshenziswe madoda imisiwe ukuthomba elihlobene ne hypofunction of nezindlala ngokobulili, cryptorchidism, spermatogenesis kahle. Cabanga kunazo owaziwa Analogue "pregna" kulesi sihloko.

Incazelo "Pregnil" izidakamizwa

"Pregnil" kuhlanganisa gonadotropin chorionic (hCG), abantu. Lokhu i-hormone ukuqala ukukhiqiza izicubu chorionic ekupheleni umbungu yenzeka inqubo. HCG has FSH nomsebenzi LH kwandisa uketshezi estrogen iphinde iqalise inqubo ukukhiqizwa kwamaqanda. Ngemva kwalokho-ke isekela Corpus obusebenzayo luteum umsebenzi ngaphambi ukukhiqizwa estrogens futhi progesterone placenta.

Isicelo exogenous chorionic womuntu gonadotropin hhayi kuphela sithuthukisa uketshezi estrogen wesibeletho kanye progesterone, kodwa futhi eheha nge-ovulation, luteal kusiza okwalandela Ekhala follicle.

Ukusetshenziswa hCG amalungiselelo has nekusebenta enkulu yesifunda ngenhloso womuntu menopausal kwama-hormone follicle.

zemithi

"Pregnil" (analogue "pregna" isivakashi at umthamo ofanayo) ikhishwe 1500 futhi 5000 imithamo i-MO. Isetshenziselwa ujove esicutshini.

Ekwelapheni anovulatory ukungazali e abesifazane Kunconywa umjovo owodwa Nkonzo 5000-10 000 Wezokuvikela, ekupheleni inkambo yokwelapha of FSH (follicle eqabulayo-hormone okuthiwa i) noma HMG (womuntu menopausal gonadotropin).

Ngaphambi wokubhoboza, ukulawula ukushukuma wesibeletho iqondiswa emva kokwelashwa 5000 i-MO.

Sekela esigabeni luteal Kwenziwa ngomjovo eyindilinga ngesikhathi umthamo 1000 kuya ku-3000 i-MO njalo ngemva kwezinsuku ezintathu - izikhathi 3.

Abesilisa esetshenziselwa hypofunction of nezindlala ngokobulili futhi ukuhlukumeza ka spermatogenesis at esenikwe 1000 kuya ku-2000 i-MO kaningana ngesonto (analogu ka "pregn" ingase ikhishwe ngendlela efanayo).

Ekwelapheni cryptorchidism lisetshenziswa izingane izidakamizwa izikhathi 2 ngesonto, Kunconywa Isikali:

- kuze kube iminyaka engu-2 - 250 i-MO;

- kuze iminyaka 6 ukuqoka 500 1000 i-MO;

- emva kweminyaka 6 - 1500 i-MO.

Sesihlole isicelo kohlelo zomuthi. Kodwa okuhle nakakhulu ngaphambi kokuqala ukwelashwa kudokotela futhi uthole aphoyintimenti kusuka kuye izidakamizwa.

Analogs "pregna»

Yiziphi belungiselela "Pregnil" nozakwabo? Eqinisweni, eziningi zazo, kukhona izidakamizwa ashibhile, kukhona eqolo.

"Chorionic gonadotropin"

"Chorionic gonadotropin" kuyinto eziphansi Analogue "pregna." Ikhishwa ngezilinganiso 500; 1000; 1500 ED. It isicelo intramuscularly. Iphathwe in umthamo ka 1500 IU usuku noma 3000 izikhathi IU 2-3 ngesonto ekwelapheni ukungabi nenzalo kwabesifazane. Ekwelapheni infantilism ngokobulili ukhombe 500 kuya 1000 IU kanye ngesonto, izifundo izinyanga 2. Izingane ukhombe 500-1000 MO nge iminyaka eyishumi, bese - 1500 IU kuze kuphele inyanga nge okuphindaphindiwe course. Okusho ukuthi, lesi sidakamizwa "Pregnil" analogue zishibhile.

"Ovitrel"

"Ovitrel" yakhiwa-alpha horiogonadotropin. Ikhishwa ngezilinganiso 250 micrograms (6500 IU). It isetshenziswa phansi kwesikhumba. Kuvuselela ukwakheka Corpus luteum, follicle nokuvuthwa kanye nge-ovulation. 250 g elilingana amayunithi 5000 ka human chorionic gonadotropin. Lapho ukukhuthazwa superovulation wesibeletho futhi wamukele 250 .mu.g esetshenziswa, ngemva Yiqiniso yokwelapha noma womuntu menopausal FSH. Ekwelapheni anovulation umthamo engabelwe 1 usuku ngaphambi kokuya ocansini.

"Horagon"

Enye Analogue "pregna." Itholakala umthamo 1500 futhi 5000 i-MO. Iphathwe intramuscularly. Isetshenziselwa dysmenorrhea, gonads hypoplastic, infantilism ngokobulili ukusheshisa ukuthomba, usongo isisu nokuguqulwa, ntombazane superovulation. Ntombazane superovulation yaphathwa a umthamo 5,000 ukuze 10,000 MO nge esisodwa. Ekwelapheni isisu komkhuba kutuswa ukusebenzisa ngosuku lokuqala ukusungulwa sokukhulelwa amasonto 14, kabili ngesonto 10 000 i-MO. ukuphathwa hypogonadism yakhiwa esasikhipha kusuka 1,500 kuya 6,000 MO nge kanye ngesonto. ukuntula Androgen ezingabantu ziphathwe ukusetshenziswa hCG 1 njalo emavikini amabili izinyanga ezintathu.

"Choriomon"

Ikhishwa ngezilinganiso 5000 IU / ml kwezokuphatha esicutshini. Kuyinto ngempumelelo kakhulu ekwelapheni anovulatory imijikelezo futhi amenorrhoea. Sisetshenziswa ndawonye menopausal womuntu gonadotropin (75 i-MO) izinsuku ezingu-10 phansi kwesikhumba noma intramuscularly, ukuze andise uketshezi of estrogens. Lapho ultrasound follicle ovuthiwe ucele nge-ovulation lokungeniswa iqondiswa kusukela 5000 kuya ku-10 000-MO nge "Choriomon". Umuthi iqondiswa izinsuku 1-2 emva umjovo lokugcina FSH noma HMG. Sexual hlangana Kunconywa nsukuzonke kuze ukukhiqizwa kwamaqanda.

Okungavundile ngenxa enganele isigaba luteal "Choriomon" wasebenzisa 5000 i-MO 21, 23 nezinsuku 25 umjikelezo.

"Profazi"

"Profazi" - fanekiso ukuba "pregna 5000". Itholakala umthamo 2000 futhi 5000 i-MO. It isicelo intramuscularly. Ukwelashwa anovulatory ukungazali uqhutshwa ngokwethula 10 000 MT phakathi umjikelezo, emva kokwelashwa ne HMG noma FSH. Ntombazane superovulation liqoke i-MO 10000 ngelanga kocingo neqanda. Lapho Corpus luteum esingamahlalakhona Kunconywa ukuphatha i-MO 5000, futhi eyesihlanu Ngosuku lwesishiyagalolunye emva nge-ovulation. "Profazi" kuphumelela kakhulu ekwelapheni kwesisu yansukuzonke. It is esetshenziswa 10 000 MO nge e isicelo kuqala, bese - ku 5000 wezokuVikela kabili ngesonto amasonto 14.

Izimo

Izimo ukusetshenziswa hCG amalungiselelo:

- nambili kuya kwabadala.

- izimila-hormone okuthiwa i-producing we nezindlala zangasese.

- izimila hypothalamus futhi pituitary indlala.

- izimila esibelethweni akuhambisani nokukhulelwa.

- Thrombophlebitis.

- i-hypothyroidism.

- noTubhali sokukhulelwa umlando izinyanga ezintathu ngaphambi kokwelashwa.

- esibelethweni Polycystic.

- lactation.

side effects

Imiphumela engemihle evela ukusetshenziswa human chorionic gonadotropin:

- ukucasuka yanda, lability ngokomzwelo, ukuphathwa ikhanda, nokukhathazeka.

- iziyaluyalu dyspeptic (isicanucanu, ukuhlanza).

- ukuzwela ekhulile yemiphumela izingono.

- Gynecomastia ezingabantu.

- amawala, isifuba.

- Syndrome ka hyperstimulation wesibeletho.

- A ukwanda yesikhashana wenduku, ukwakhiwa ongaphilile.

- Ukuncishiswa indlala pituitary.

- Ukuncishiswa afundwa igazi ivolumu (hypovolemia).

- ekuqongeleleni igazi e komgodi ongaphakathi kwamathumbu.

- Thromboembolism.

- ukukhulelwa amaningi.

- Fluid nokugcinwa, uzwakalise, edema ezivamile.

Analogue "pregna 1500" bahluleka ukukhubazeka azalwa naso kwesibeletho, futhi ezihlobene lwesitho sangasese sowesifazane, ukuvuvukala kule amashubhu fallopian, eyinhloko ukwehluleka wesibeletho, izimila fibrotic esikhulu kwesibeletho.

wonke Ukwelapha ithatha indawo ngokuqinile ngaphansi uchwepheshe kokuqondisa nokulawula izinguquko ukuhlaziya, ukusetshenziswa kwalezi izidakamizwa ekhaya akuvumelekile futhi kungase kube nemiphumela ungalungiseki empilweni.

Ukwelashwa nokuvikelwa anovulatory ukungazali kufanele kwenziwe ngaphansi ultrasound ukulawula follicle ukukhula nokuhlola okuqhubekayo Inkomba wesibeletho.

ukuqapha Okubalulekile yansuku zonke lokuhlushwa estradiol. Nge izimpawu okungafunwa wesibeletho ukwelashwa hyperstimulation chorionic gonadotropin is anqanyulwa ngokushesha.

Sesihlole emuthini "Pregnil" analogue, ukusetshenziswa ukuze zibaqondise uphindze uchazwe.