ALT kuyinsakavukela

Alanine aminotransferase (ALT) - one of the izinkomba main e izilonda amaseli isibindi senhliziyo esilimele. izinkomba zokuveza indlela ukusebenzisa ALT - a ukulimala kwesibindi anobuthi, izivivinyo zokuvimbela kanye ne-hepatitis ezibangelwa amagciwane.

ALT kuyinto-enzyme zihilelekile umzimba yeselula amino acid. Inani enkulu yalo - e izinso, isibindi, imisipha lwamathambo kanye inhliziyo. Njengoba ALT itholakala ngokuyinhloko cytoplasm amaseli, yikuphi ukulimala ithwala ukwanda okuqukethwe noma umsebenzi waleli enzyme.

In izifo oyingozi noma ezingamahlalakhona kungaba lesion organic, okuyinto iyolandelwa necrosis omsakazo amaseli eziholela ophumayo ALT lingene egazini kusukela lesion. Ezinye ukwanda umsebenzi we enzyme acute isilethikusebenza kwenzeka cishe ngo-6 -. 12 amahora, futhi kuvumelana isiqongo womsebenzi ALT.

Isici kakhulu ukwanda egazini ALT umsebenzi e izifo zesibindi ukuthi ahambisana sokusha kwesibindi noma imiphumela anobuthi. Futhi ALT enzyme kuyinto inkomba kobukhulu kwesibindi izilinganiso A, B no-C Hhayi ucabangela etiology, isifo sokusha kwesibindi kohlobo acute, umsebenzi ALT zingandiswa kayishumi futhi abangele jaundice.

Kakhulu ukwanda okusezingeni eliphezulu e umsebenzi enzyme ibizwa ebonwe acute ukusha kwesibindi kohlobo ezibangelwa amagciwane. Ngezinye congenial umsebenzi isifo kulo lonke ukuzinza senzeka ngenyanga. Uma kwenzeka ukuthi le nkathi kwaba eside, kungase kukhombise aphuma acute yesifo sokusha kwesibindi kohlobo ezingamahlalakhona.

Lapho i-hepatitis okungamahlalakhona, metaphases kwesibindi, nomdlavuza wesibindi, kanye mononucleosis ezithathelwanayo kunokwanda okuncane emsebenzini ALT. Futhi alanine umsebenzi aminotransferase kungase kwandise e isilethikusebenza, kodwa kakhulu kancane, okungenani eqhathaniswa aminotransferase aspartate (AST). Ukuze ukuletha ukusazi ngokunembile isifo esikuphethe kakhulu nje, ukuvaleka kwegebe ukubala de Rytis, okuyinto isilinganiso AST emsebenzini ALT.

AST ALT izinga 1.3 ± 0.4. It is kudlulwe e kokunqotshwa imisipha yenhliziyo. Necrosis lamaseli sesibindi esingelapheki kubantu abangamaphesenti viral ukusha kwesibindi kohlobo ALT AST izinga kuyehla kube 0.6 - 0.8. Lezi zinombolo abasakwazi kusandile e-Ukraine nase-Europe, kodwa ngesisekelo namakhemikhali athile, lezi zibalo ingahluka kakhulu. Zonke incike isethi we reactants ukuthi ukucacisa ALT enzyme AST kanye laboratories ekutholweni transaminase izinkomba ngokuvamile unamathisele izinga.

Ngo-hepatitis acute, amazinga ALT kudlulwe kuyinsakavukela aminingi ukudlula UMTHETHO. A isilethikusebenza weqiwe isikhathi eside. Njengoba elinikeziwe isifo ALT izinga inyuka kancane de Ritis Coefficient inyuka kakhulu. A viral ukusha kwesibindi kohlobo ALT izinga ukubuyiselwa emasontweni ambalwa.

Ngo abadala nezingane ngonyaka amadala kweyodwa ngoba amadoda kuba amayunithi 10-40 ilitha legazi ngalinye, futhi abesifazane - 7-35. Kusukela ekuzalweni kuya onyakeni owodwa ALT izinga ezinganeni amayunithi cishe 13 kuya ku-45 ilitha legazi ngalinye.

Izinkomba salokhu ukuhlaziywa ngokuvamile kwesibindi isifo uphethwe, ukuxilongwa umehluko, ukuhlolwa donor, izifundo ukugqashuka kwesifo sokusha kwesibindi sohlobo, esivimba amanzi zokugula zinkulu, kanye lwamathambo imisipha isifo.

amazinga ALT kufanele kuhlaziywe esiswini esingenalutho ekuseni, ngoba ngesikhathi izinga usuku zingase zishintshe. Inkomba zingandiswa kwenzeka ukuthi esisindo ingaphandle kuyinsakavukela.

Isifundo ku-ALT ekhiqizwa indlela kwamakhemikhali usebenzisa serum ngaphandle hemolysis ngendlela ekhethekile test tube ngesivalo obomvu noma plastic isikulufa cap. amasampula elondolozwe akuzona esingaphezu kosuku.