Amasosha Omzimba ukuze yegilo peroxidase

Thyroid peroxidase enzyme iyinhlangano nature glycoprotein. Lokhu antigen microsomal iyona ebaluleke kunazo zonke yokuthola izinhlelo zamagama kwama-hormone egilo.

Inqubo sokuhlasela kwamasosha omzimba ezihilela autoantibodies ezicutshini obumba indlala yegilo. Ukuphazamiseka umsebenzi yegilo ngokuvamile ehambisana nakho. Lokubaluleke kakhulu kulesi simo kukhona amasosha omzimba ngokumelene yegilo peroxidase.

Ubuningi eliphakeme ezitholakele thyroiditis Hashimoto sika. Esikhathini sekugcina izinqubo atrophic kule ndlala izinga labo lehliselwa kwezinye izimo emazingeni alibonakali.

Amasosha Omzimba ukuze yegilo peroxidase zivame ukubizwa-Graves 'disease. Isikhathi ukuhlonza kwabo isifo esihlobene engcupheni ukwakheka alandelayo hypothyroidism.

Lapho ezifweni ukuze tireoditu Hashimoto abesifazane babe namasosha omzimba tireperoksidaze kungatholakala ngesikhathi sokukhulelwa. Nge lokuhlushwa babo yanda senyanga yokuqala kukhona amathuba asathuthuka lesi sifo ngemva kokubelethwa.

Amasosha Omzimba ukuze yegilo peroxidase futhi kungase kubonise kwabanye pathologies yegilo. Lezi zihlanganisa, ikakhulukazi, kufanele kufake adenoma, goiter, umdlavuza yegilo. Ngaphezu kwalokho, amasosha kukhona detectable in abantu enempilo (cishe ama-10% abesifazane 5% amadoda).

ucwaningo Laboratory ku ukuhlonza yabo kufanele kwenziwe kungakhathaliseki ukuthi uhlobo inqubo sokuhlasela kwamasosha omzimba. Kuyinto ayihlukile neze futhi sikashukela (insulin-kuncike), anaemia eziyingozi, esingamahlalakhona adrenal (sokuhlasela kwamasosha omzimba), omzimba izicubu erythematosus.

Isicelo izidakamizwa angabeka avuse ukuthuthukiswa hypothyroidism, okuyinto lihlotshaniswa ukubukeka autoantibodies. Lezi zihlanganisa, ngokukhethekile, lithium izidakamizwa, "Amiodarone". mphumela sici yokwelapha immunostimulatory (isib, interferon).

Ukunqunywa amasosha omzimba ngokwanele test ebucayi ukuze kutholwe nolokubhujiswa sokuhlasela kwamasosha omzimba we indlala yegilo. Ngakho ngo kunani lokuhlonza ncamashi amaphuzu.

Qaphela ukuthi ukusungula khona i isifo sokuhlasela kwamasosha omzimba we indlala yegilo kuphela ngesisekelo the ezikhonjwe Inkomba okusezingeni eliphezulu amasosha omzimba engenakwenzeka.

izinkomba Ingabe Ohulumeni Banalo Lonke isifundo kuyinto-Graves 'disease, isibikezelo ingozi hypothyroidism kungemuva elingalodwa okwandisa lokuhlushwa i-hormone yegilo-inkanuko. Ngaphezu kwalokho, isidingo kuhlaziya kwenzeka e thyroiditis sokuhlasela kwamasosha omzimba hypothyroidism eyinhloko, kanye umhlahlo ukuthuthukiswa kwangemva kokubeletha thyroiditis e iziguli engozini.

Ukuze izinkomba isihlobo zihlanganisa

- umehluko ukuxilongwa subacute futhi sokuhlasela kwamasosha omzimba (lymphocytic) thyroiditis ku isizinda thyrotoxicosis Transistor,

- Ukuxilongwa amafomu sokuhlasela kwamasosha omzimba ku isizinda ngokukhukhumala kwentamo euthyroid noma goiter nodular,

- ukubikezela hypothyroidism e iziguli engozini, ukukhulelwa ekuseni.

Esikhathini ekwelapheni izifo ezikhonjwe cwaningo ozolandela okungalungile. Lokhu kungenxa yokuthi amazinga ayo ayibalulekile prognostic kalula uma zitholakale isifo.

Ephambi kwezinduna amathuba sokuhlasela kwamasosha omzimba yegilo isifo watusa retested ngonyaka wokuqala nowesibili observation esimweni kulolu cwaningo eyinhloko, akukho amasosha yegilo peroxidase. Sivamile umuntu enempilo isesikhathini 35 IU / ml.

Namuhla abukho zokwelapha ngokwesayensi kungase kutholakale futhi umsindo ngesikhathi AIT (thyroiditis sokuhlasela kwamasosha omzimba). Ndawonye nalokhu, ku isizinda hypothyroidism esungulwe, yegilo peroxidase amasosha omzimba uma bevuselwa, ukwelapha isifo akuyona inkinga lodokotela. Aqokwe hormone yokwelapha izidakamizwa "Levothyroxine."