Umuthi 'Algezir Ultra ": yokusetshenziswa, incazelo, ukwakheka kanye nokubuyekeza

I "Ultra Algezir" odokotela bavame linqume iziguli muva. Imiyalo le ndlela kuyinto kunalokho ulwazi futhi uchaza izici isicelo sokuba izigaba ezahlukene iziguli, kodwa kunokuba ulwazi oluphelele mayelana ithinta indlela umzimba kusho.

kwemithi

Njengengxenye izindlela - ama-NSAID, okuyinto esuselwe naftilpropionovoy acid. Ngo inqubo Uthola le izidakamizwa ine anti-inflammatory, antipyretic futhi isenzo analgesic, njengoba ngokuvamile kuboniswa Izibuyekezo "Algezir Ultra". Umhlahlandlela luhlobo futhi ukhomba le mininingwane.

Lo mshini wezenzo zomuthi lihlanganiswe ngokuqondile okusithiyayo of Cox enzyme ezikhethekile ephakamisa prostaglandidov zivimbela synthesis arachidonic acid. Futhi, le ndlela inikeza okusithiyayo of platelet wokuhlanganisa.

ngokukhethekile kufanele ikhokhwe yokuthi e inqubo ukuthatha ubuhlungu izidakamizwa encishisiwe, kuhlanganise ubuhlungu emalungeni kunyakaza futhi uphumule. Ngo inqubo yokuthola encishisiwe ukuvuvukala ngokuhlanganyela, ekuseni ukuqina, ukwandisa ububanzi motion, othi cishe wonke umuntu ushiye amazwana mayelana «Algezir Ultra" lisho ukuthini. Imiyalelo ulwazi olufana sihlanganisa, ngesikhathi esifanayo khona uphawula futhi yokuthi umphumela anti-inflammatory bungatholakala ekupheleni ngesonto lokuqala ukwelashwa okusebenzayo.

Pharmacokinetics

Ngemva kwalokho, yokwamukela ithuluzi ku naproxen iqala ugxile ngokushesha esuka pheshana emathunjini. Inkomba C _max plasma siqala okuqhubekisela esidlule 1-4 amahora ngemva ukungenisa. Kufanele kuqashelwe ukuthi ukusetshenziswa ngesikhathi esisodwa imithi nge ukudla kungase kukwenze wephuze ngesilinganiso ukumuncwa, kodwa akazange ukwehlisa izinga isiyonke ukumuncwa. Naproxen kuyahluka ukumuncwa ngokwanele ezinhle esimweni ekuphathweni rectal, kodwa kulokhu kukhona ukumuncwa ahamba kancane kakhulu kunalokho, uma iqhathaniswa umzila ngomlomo.

Ngezinye lokuhlala oqabulayo isici asebenzayo sibopha ukuthi plasma amaprotheni cishe 100%. I lokuhlushwa naproxen ku inyuka plasma kulingana ngesikhathi ukusetshenziswa ngemithamo ofika ku-500 mg, kuyilapho ngesikhathi ngemithamo ephakeme kukhona nokwanda kokungabi imvume, okuyinto kubangelwa ukugcwaliswa ephelele amaprotheni oketshezi olungenambala olusegazini.

Naproxen lisabalalisa ku uketshezi lwamalunga.

T _1/2 amahora ngu-13. Mayelana 95% inani umthamo ekugcineni excreted ku umchamo esimweni unmodified, 6-O-futhi conjugates yayo dezmetilnaproksena ahlukahlukene. Yonke enye into esikhathini esizayo esiseduze ngemva kokuthatha excreted endleni yabantu abanaleli.

Isikali

Kuyaphawuleka ukuthi Kunconywa imithamo ngazinye ukusungulwa ngokuhambisana kobukhulu isifo lesiguli. Ngu izidakamizwa "Algezir Ultra" imfundo ibonisa ukuthi kunconywa abadala ukuthatha ngemithamo of 0.5-1 g ngosuku ngemithamo ezimbili, kuyilapho ezhednevnayadoza ukulapha evamile yesondlo kufanele kube ngu-500 mg.

Umkhawulo kungenzeka umthamo zonke izinsuku we 1.75 g

Umthamo izingane

Uma impatho wenziwa iziguli ezineminyaka ephakathi kuka-iminyaka-1 kuya 5, kuleso simo kufanele lisetshenziswe ku-2.5-5 mg ngayinye kg ngosuku 1-3 reception nsuku zonke, esiphezulu ukwelashwa okungcono kakhulu ongakuthola kuleli icala kungaba 14 izinsuku. Esikhathini nokwelashwa arthritis ezincane izingane abaneminyaka engama-5, umthamo wansuku zonke iqinile futhi 10 mg ngayinye kg.

Izidakamizwa ukuxhumana kusho "Algezir Ultra"

Yokusetshenziswa Kuyaphawuleka ukuthi, ukube bekunjalo lokhu kubathinta kabi ukumuncwa naproxen, okuyinto ebaluleke ngempela ekwelapheni uma isetshenziswa ngesikhathi esisodwa antacids, okuhlanganisa aluminium, magnesium, kanye sodium hydrogencarbonate.

Uma ithuluzi lisetshenziswa ngezincazelo anticoagulants ngokungaqondile, kungase kube khona ezincane okhulisa isinyathelo le mithi ukuthi Kuye kwaphawulwa ngokuhamba izifundo zokwelapha ezikhethekile.

Futhi ngesikhathi ucwaningo ke wahlolwa umphumela ukusetshenziswa ngesikhathi esisodwa amoxicillin izidakamizwa, ukuze ezimweni ezithile waqala ukuthuthukisa nephrotic syndrome. Uma "Algezir Ultra" yasetshenziswa acetylsalicylic acid, kwezinye izimo encishisiwe emakamu ingqikithi naproxen e oketshezini olungenambala lwegazi.

izici engeziwe nokuxhumana

Ngaphezu kwalokho, kuyafaneleka lezi zimo ezimbalwa ezedlulele ukuthi ebaluliwe emuthini "Algezir Ultra" (amaphilisi) Yokusetshenziswa:

• ngenkathi usebenzisa sihlinzekela izinguquko ezithile pharmacokinetic Amapharamitha diazepam;
• Uma ithuluzi sisetshenziswa kanyekanye ne-caffeine, naproxen umphumela bungathuthukiswa;
• ukusetshenziswa kuhlangene lithium carbonate luhlinzeka ukuthi kungenzeka okwandisa emakamu lithium-plasma yegazi;
• lihambisana methotrexate kwandisa ubuthi ketshezi;
• lapho "Algezir Ultra" lisetshenziswa kanyekanye probenecid incipha emakamu ingqikithi naproxen e oketshezini olungenambala lwegazi;
• isicelo kanyekanye ivumela salicylamide ukuthuthukisa isenzo we ketshezi.

Kunemibiko okubonisa ukuthi uma ithuluzi isetshenziswa ngesikhathi esifanayo ne-morphine, ekugcineni, lokhu kungase kuholele ekubeni ukuthuthukiswa myoclonus. Futhi, ngenkathi usebenzisa prednisone waphawula nokwanda okuphawulekayo degree of lokuhlushwa ketshezi oketshezini olungenambala lwegazi. Ngaphezu kwalokho, njengoba kuphawuliwe lesicelo ngokwehlukana ngesikhathi esisodwa furosemide ohlinzekela nokuncipha umphumela isisu we ketshezi. Lokhu kuphawulwe ku isikhungo ezifana izidakamizwa "Algezir Ultra" ukubuyekezwa. Ukufundiswa Sibonisa kulesi sici zomuthi.

Nokukhulelwa kanye lactation

uqaphe kakhulu Kunconywa ukusebenzisa lolu izidakamizwa kwabesifazane abakhulelwe noma lactating, futhi ikakhulukazi lokhu kusebenza futhi nakulabo okwamanje uhlala senyanga yokuqala noma wesithathu. Lonke iphuzu lapha liwukuthi emva kokuthatha lesi naproxen izidakamizwa uqala ukungena ngokusebenzisa isithiyo esinomhlapho, futhi kamuva kudedelwa eziningi ezincane e ngobisi lwebele.

side effects

Kuhle kokusho ezimbalwa side effects ukuthi ebaluliwe emuthini "Algezir Ultra" imfundo manual. Izincazelo kulokhu ayatholakala ku ngamaqembu ahlukene ejensi:

• Isimiso sokugaya ukudla bungene. Phakathi reception kungenzeka ukuhlanza samanje, isicanucanu, ukungakhululeki ku epigastrium. Ezimweni ezingavamile erosive zabonakala futhi izilonda emathunjini yokusetshenziswa pheshana emathunjini, kanye ezihlukahlukene normal isibindi umsebenzi ukopha.
• Isimiso sezinzwa esiyinhloko. Uma usebenzisa kwezinye iziguli khona ukozela, ikhanda, futhi ekunqandeni isivinini lengqondo ukusabela. Ezimweni ezingavamile kakhulu, isicelo kwaleli thuluzi, kukhona kwempilo ukuzwa, njengoba kufakazelwa izidakamizwa "Algezir Ultra" imfundo manual. Abstract alimchazi ngokuningiliziwe ukusetshenziswa lesi sici.
• uhlelo hematopoietic. Kakhulu thukela esebenzisa izidakamizwa kuholela okuvela granulocytopenia futhi thrombocytopenia futhi hemolytic noma unenkinga yegazi eliphansi aplastic.
• uhlelo zokuphefumula. Ezimweni ezingavamile angagcina inyumoniya eosinophilic.
• Uhlelo urinary. Ezimweni ezingavamile, kungase kubangele thuthuva ezihlukahlukene nokusebenza kwezinso.
• komzimba. Ngo iqembu ethile iziguli ngokuhamba nophenyo waphawula urticaria, ukuqubuka, angioedema, okuyinto ukusabela lalivamile iguliswa izingxenye ezihlukahlukene ezakha izidakamizwa, njengoba kushiwo "Ultra Algezir" imfundo manual. Ukwelashwa kulesi simo angeke okwesikhashana.

Ngaphezu kwalokho, ukunakekelwa okukhethekile ufanelwe futhi iqiniso ukuthi esimweni yokusetshenziswa rectal, kukhona ingozi uketshezi lwamafinyila kusukela nengcosana igazi noma okuvela sokuzikhulula ezibuhlungu.

Lapho isetshenziswa?

Kule minyaka embalwa, odokotela yesimanje ngokuvamile ngokwanele kuqalile ukuba linqume ukuba iziguli zabo leli thuluzi ekwelapheni ezihlukahlukene izifo, kuhlanganise nalezo ezichazwe "Ultra Algezir" imfundo manual. Intengo yaleli izidakamizwa kuyatholakala cishe kuwo wonke umuntu, ngokuqondene ngalo futhi evame ukunikezwa esikhundleni iningi elikhulu izimali efanayo.

Ikakhulukazi, kuyafaneleka a izifo ezimbalwa eziyisisekelo, ukuphathwa zazo isetshenziswa kakhulu esebenzayo:

• osteoarthritis;
• rheumatoid arthritis;
• ankylosing spondylitis;
• sifo acute;
• syndrome articular;
• neuralgia;
• myalgia;
• ubuhlungu yomgogodla;
• ukuvuvukala ebuhlungu kwezicubu ezithambile noma uhlelo zemisipha.

Ngaphezu kwalokho, "Algezir Ultra" ngokuvamile kuba asizayo ekwelapheni izifo ezihlukahlukene ezithathelwanayo futhi sokuvuvukala ENT, dysmenorrhea eyinhloko, adnexitis, kanye yamazinyo nekhanda.

Izimo

Kukhona Ezimweni ezimbalwa lapho leli thuluzi akumelwe lisetshenziswe, futhi sikhomba lesi sidakamizwa "Algezir Ultra" yokusetshenziswa (incazelo). Izibuyekezo Odokotela futhi ngokuvamile babonisa ukuthi lesi izidakamizwa is hhayi Kunconywa kwalezi zimo:

• "Aspirin triad";
• zonke izinhlobo erosive kanye izilonda emathunjini e pheshana emathunjini;
• eshiwo ngokucacile iziyaluyalu kumsebenzi kwezinso;
• uhlelo hemodyscrasia;
• eshiwo ngokucacile iziyaluyalu e kokusebenza kwesibindi;
• ukuzwela kakhulu ukuba naproxen kanye nezinye izinto afakwe indlela yokwakheka izidakamizwa.

Phakathi kwezinye izinto, ukusetshenziswa kwaleli thuluzi is hhayi Kunconywa izingane ezingaphansi kweminyaka engu-unyaka owodwa, njengoba kufakazelwa izidakamizwa "Algezir Ultra" imfundiso. Intengo leli thuluzi ruble 85-90. amaphilisi 10.

Izixwayiso

ukunakekelwa Extreme kufanele ithuluzi lisetshenziswe ekwelapheni izifo ezihlukahlukene nezinso isibindi, pheshana emathunjini emlandweni, kanye senhliziyo, umfutho wegazi ophakeme noma khona izimpawu dyspeptic. Ikakhulukazi, okuphoqelekile kumele ukuba bonana nodokotela wakho mayelana nokuthi kungenzeka ukusebenzisa izidakamizwa ngemva ukungenelela okukhulu kuhlinzwa.

In the ukwelashwa kufanele ngaso sonke isikhathi kugcinwe ukulawula esihleliwe ukusebenza kwe-izinso futhi isibindi, kanye neuropathy igazi isithombe. Uma kudingeka, zama ukuthola ukuthi lokuphuma phambili okumisiwe lokuhlushwa 17-ketosteroids ethola naproxen ngempela udinga ukukhansela elinye amahora angu-48 ngaphambi kosuku kulindeleke cwaningo.

ngokukhethekile kufanele ikhokhwe yokuthi ngokuthatha izidakamizwa kuthinta ikhono ukushayela imoto ezokuthutha kanye nokuphathwa kwe-izindlela ezehlukene zokwenza lokhu. Kule ndaba, kungcono nomkhawulo lukugweme iyiphi imisebenzi yingozi kuhlobane ngokuqondile isidingo okuhlushwa futhi ngakhula ijubane lengqondo ukusabela njengoba isicelo "Algezir Ultra". ekufakweni kwesicelo imiyalelo ukulungiselela eceleni Leli phuzu ligcizelelwa.