Wegener sika granulomatosis - Izimbangela, izimpawu, ukwelashwa.

granulomatosis Wegener sika - kuyinto isifo sokuhlasela kwamasosha omzimba libhekene ukuvuvukala kwemithambo emincane kanye emithanjeni. Ezimweni eziningi umfula avuvukele kokunikeza igazi sinuses, wamaphaphu izinso nezicubu kuphela kodwa ngaphezu kwalokho, kukhona bobunjwa esinqunyiwe kwenzeka ukuthi sithinta umuntu oyedwa ala maqembu kuphela. Nge granulomatosis olubanzi cishe njalo ngimangaliswe kokubili amaphaphu nezinso zombili. Kuleso simo, uma abathintekayo kukhona ukukhanya kuphela noma nje izinso, iyisifo ngokuthi granulomatosis Wegener sika akuphelele.

granulomatosis Wegener sika nkinga ivame kakhulu kubantu abasebasha noma oseqinile, cishe ngaphandle ukuhlangana izingane. Kodwa, noma kunjalo, lesi sifo singumbulali uyakwazi kuthinta wonke amaqembu wobudala. izibalo Ubulili ukunqoba lesi sifo uhluke abalobi ezahlukene.

Izimbangela zesifo

Izimbangela zezifo ezifana, ezifana granulomatosis Wegener sika, namuhla bengayiqondi ngokugcwele. Ochwepheshe abaningi bakholelwa ukuthi imbangela isifo kungaba ejenti viral, ngoba granulomatosis Wegener ngokuvamile kwenzeka ngemva lokugoma, SARS, ukwelashwa ama-antibiotic noma ukuchayeka. Kodwa, ngeshwa, umenzeli microbial Namanje hhayi esabiwe, ukuze isifo njengesenzo sokuhlasela kwamasosha omzimba.

Ezinye iziguli ukudida poradenitis futhi granulomatosis Wegener sika. Kufanele kuqondwe ukuthi ukufana izimpawu izifo ezimbili ezihlukene ngokuphelele ngoba kuphakama ngenxa Amagciwane webhaktheriya (chlamydia) poradenitis, kuyilapho granulomatosis Wegener sika kuyinto isifo sokuhlasela kwamasosha omzimba.

Izimpawu kanye ifomu isifo

granulomatosis Wegener sika usungaqala kungazelelwe, kodwa kungase kukhuphukele emakhaleni ami kancane kancane. Uphawu lokuqala lesi sifo kungaba kubhekwe lokushisa subfebrile, bese-ke kunciphe iphango. Ngemva kwalokho lokushisa iqala avuke, futhi intuthuko isifo.

Izimpawu ezivame yalesi sifo zihlanganisa:

- kwesisindo;

- ukukhathala;

- ukhulisa izinga lokushisa;

- ubuhlungu emalungeni;

- ubuhlungu nokuvuvukala itheku.

Ngaphezu kwalokho, lesi sifo kungathinta izingxenye ezihlukahlukene zomzimba, enikeza izimpawu ezahlukene ngokuphelele. Isibonelo, nge ukunqotshwa yangaphandle zokuphefumula amakhala yisisu nge ezingemnandi ubovu ukwahlukana olunegazi, necrotic mucosa acinene, kanye nolwanga esithambile futhi amalaka.

Ifomu generalized lesi sifo unika kwezinyanga ezimbalwa, isimo esibucayi kwesikhumba, ikakhulukazi, zibukeka ukopha nodular, izakhi necrotic, futhi kwezinye amaqembu iziguli, pericarditis, myocarditis noma ukucinana kwemigudu yokuphefumula.

sitholakele isifo

Ngokuyinhloko esolwa iziguli Wegener sika granulomatosis ngizodabula urinalysis ngokuba khona wamaprotheni ne abomvu lamaseli umchamo. Ngaphezu kwalokho-X-ray zenziwa sinuses nasesifubeni, ukubona izinguquko sokugembula. Ngaphezu kwalokho, ukuhlaziya igazi kuthathwa futhi, ngokukhethekile, kunqunywa ESR namaprotheni C-esisheshayo. Kukhona ukuhlaziywa eziyinkimbinkimbi ngokwengeziwe, kodwa futhi kuphumelele kangcono ukukhomba antineyrofilnyh amasosha omzimba cytoplasmic.

ekwelapheni lesi sifo

granulomatosis Wegener sika, ngaphandle ukwelashwa okufanelekile isiguli bungase buholele ukufa ngaphakathi kwezinyanga ezimbili kuya kwezintathu. Konke ukwelashwa ikakhulukazi okuhloswe ngazo nokucindezela izivikeli mzimba, kanye ukusabela ukuvuvukala wendawo. Izidakamizwa ezithandwa kakhulu corticosteroids futhi cyclophosphamide. Le mithi kufanele kuthathwe kuze ukuthethelelwa sifo, bese hhayi ekubhemeni isifo Hodgkin sika, kungenziwa wanezela kubo kodwa futhi methotrexate, okufanele kuthathe kweminyaka embalwa.