Angiotensin yokwamukela blocker 2: izidakamizwa izindlela yesenzo

Bobabili nokwelashwa kwezifo zenhliziyo kudinga indlela onokwethenjelwa futhi sina. Izinkinga ezinjalo kuba uyabakhathalela abantu namuhla. Ngakho-ke, abantu abaningi bathambekele sibaphathe ngaphezulu kancane. Abantu abanjalo bavame indiva noma ngokuphelele isidingo ukwelashwa noma badle izidakamizwa ngaphandle udokotela (ku iseluleko abangane). Nokho, kubalulekile ukukhumbula ukuthi ezinye izidakamizwa wasiza abanye, akuqinisekisi ukuthi kuyokusiza. Ukuze ukwakheka ukwelashwa zemithi zidinga eyanele ngalokuphatselene nelwati, emakhono, abanale Ochwepheshe kuphela. Futhi nika yimuphi izidakamizwa ungakwazi kuphela kokucabangela izici ngamunye isiguli, kobukhulu kwezifo, ikakhulukazi isifo Yiqiniso ezinhle nangomlando. Ngaphezu kwalokho, namuhla kukhona imithi eminingi ngempumelelo ukuthi bakhethwa laqokwa ochwepheshe kuphela can. Ngokwesibonelo, libhekisela ohlangeni sartans - iqembu elikhethekile izidakamizwa (obizwa nangokuthi angiotensin 2 yokwamukela blocker). Ziyini lezi izidakamizwa? kanjani angiotensin 2 yokwamukela? Izimo ukusetshenziswa izinto okungezakho nokuthi yimaphi amaqembu amele paitsentov? Kwezinye izimo, kungafaneleka ukuzisebenzisa? Yikuphi izidakamizwa zifakwe leli qembu izinto? Izimpendulo zale mibuzo kanye neminye izophendulwa kulesi sihloko.

Sartana

Kubhekwe njengeqembu izidakamizwa ubizwa ngokuthi kanje: angiotensin yokwamukela blocker 2. ukwakhiwa kwaleli qembu izidakamizwa, thina ukuba yakhiqizwa Ukutadisha ngokucophelela izimbangela zezifo kohlelo senhliziyo nemithambo yegazi. Namuhla, ukusetshenziswa kwazo nezenhliziyo isiba kwande.

Angiotensin 2 yokwamukela: izindlela yesenzo

Ngaphambi kokuqala ukusebenzisa imithi, kubalulekile ukuqonda basebenza kahle indlela. luyakuthonya kanjani umzimba womuntu angiotensin yokwamukela 2? Amalungiselelo yaleli qembu abophezele receptor, kanjalo ivimbela nokwanda okuphawulekayo blood pressure. Lokhu kusiza ukuvimbela ngempumelelo nomfutho wegazi ophezulu. angiotensin 2 yokwamukela blocker kukhona ephumelela kunazo kulesi sici izinto. Ochwepheshe ukulalelisisa ngenxa kubo.

Ukwahlukanisa: angiotensin 2 yokwamukela blocker

Kunezinhlobo eziningana izinhlobo sartans ukuthi kuhluke yabo isakhiwo sazo sekhemikhali. Kungenzeka ukuba ukhethe ezifanele angiotensin nesineke yokwamukela blocker 2. Izidakamizwa okuzokwenziwa ezibalwe ngezansi, kubalulekile ukuhlola futhi nixoxe nokufaneleka ngokusebenzisa kwawo nodokotela wakho.

Ngakho, kunamaqembu sartans ezine:

• Biphenyl tetrazole nemikhiqizo.
• Nebifenilovye tetrazole nemikhiqizo.
• netetrazol Nebifenilovy.
• compounds Non-eyindilinga.

Ngakho, kukhona izinhlobo eziningana izinto, ahlukaniswa angiotensin 2. ukwakhiwa (core uhlu) receptor ethulwa ngezansi:

• "Losartan".
• "Eprosartan".
• "Irbesartan".
• "Telmisartan".
• "Valsartan".
• "Candesartan".

izinkomba

Thatha leli qembu izinto kungenziwa kuphela udokotela. Kukhona amacala eziningana lapho okungafaneleka ukusebenzisa angiotensin yokwamukela blocker 2. izici Clinical yaleli qembu amalungiselelo ezilandelayo:

• Umfutho ophakeme wegazi. Okungukuthi, abangabantwana isifo kubhekwa liyisibonelo enkulu sartans ukusetshenziswa. Lokhu kungenxa yokuthi angiotensin 2 yokwamukela blocker musa zibulale umzimba futhi akavumi ukuba Erectile Dysfunction, bronchial hhayi konakalise permeability. Effect zomuthi iqala ngemuva amabili kuya amane amasonto emva Ukuqalwa yokwelashwa.
• ukuhluleka Inhliziyo. Angiotensin 2 yokwamukela blocker zivimbela isinyathelo kohlelo renin-angiotensin-aldosterone, omisebenzi yakhe futhi wenza ukuthuthukiswa lesi sifo.
• Nephropathy. Ngenxa ngifundise ngesifo sikashukela nomfutho wegazi ophezulu, kukhona thuthuva sina ekusebenzeni nezinso. angiotensin 2 yokwamukela blocker ukuvikela izibilini akakwazi ukubonisa amaprotheni kakhulu umchamo.

"Losartan"

izidakamizwa Ngempumelelo kufakwe iqembu sartans. "Losartan" - blocker, angiotensin-2 yokwamukela umehluko Kusuka nezinye izidakamizwa nokwanda okuphawulekayo umsebenzi ukubekezelelana kubantu abaphethwe yisifo senhliziyo. Imiphumela izidakamizwa iba esiphezulu vele ngemuva kwamahora ayisithupha ukuthatha imithi. Umthelela oyifunayo kufinyelelwe ngemva kwamasonto amathathu noma ayisithupha izidakamizwa isicelo.

I izinkomba esiyinhloko ukusetshenziswa kwezidakamizwa kokubuyekezwa zimi kanje:

• ukuhluleka kwenhliziyo;
• nomfutho wegazi ophezulu;
• nokuncipha ingozi yokushaywa unhlangothi ezigulini unayo izimfanelo salokhu.

Ngeke ukwazi ukuthi usebenzise "Losartan" ngesikhathi ukuzalwa futhi ngesikhathi uncelisa, kanye esimweni ukuzwela umuntu ukuba yezingxenye ngazinye ukulungiswa.

angiotensin yokwamukela blocker 2, lapho kusebenza izidakamizwa kubhekwe kungadala ezinye imiphumela emibi njengokuba nesiyezi, ukuqwasha, ukulala thuthuva, ukunambitheka, umbono, liqhaqhazela, ukucindezeleka, inkumbulo disorder, pharyngitis, ukukhwehlela, ukucinana kwemigudu yokuphefumula, rhinitis, isicanucanu, kolwelwesi, amazinyo, uhudo, sokuzincisha ukudla, ukuhlanza, amajaqamba, samathambo, ubuhlungu ehlombe, emuva, imilenze, palpitations, ukuntuleka kwegazi emzimbeni, ukungasebenzi kwezinso, ubuthakathaka, buthakathaka libido, erythema, Alopecia, amawala, ukulunywa, ukuvuvukala, imfiva, sifo, hyperkalaemia .

Kufanele uthathe isidakamizwa kanye ngosuku, kungakhathaliseki ukuthi ukudla, ngemithamo ebekwe udokotela ukuba khona.

"Valsartan"

I nomuthi samanje liphumelele ekunciphiseni hypertrophy inhliziyo, okuyinto eyenzeka ngenxa ukuthuthukiswa nomfutho wegazi ophezulu. Ukuhoxiswa ayibonakali emva ukuqedwa zomuthi, nakuba kungenza abanye angiotensin yokwamukela 2 (incazelo sartans iqembu kusiza ukuthola ngokuthe ngqo ukuthi emithini zihlanganisa lesi sici).

I izinkomba esiyinhloko ethola into mbuzo izimo elandelayo: isilethikusebenza, umfutho ophakeme wegazi samabanga aphansi noma, congestive yokumelwa yinhliziyo.

Izibhebhe zithathwa ngomlomo. Kufanele ezokugwinywa ngaphandle ukuhlafuna. Dose uqoka udokotela. Nokho, inani eliphezulu ikhemikhali zingafundwa emini, kuba angu amathandathu, anamanci mane.

Ngezinye izikhathi kungase kudingeke emzimbeni futhi umthelela ongemuhle angiotensin yokwamukela blocker 2. Ukungaphathwa kahle imithi emzimbeni, okungase kubangele "Valsartan": kwehle libido, ukulunywa, isiyezi, neutropenia, nokulahlekelwa ukwazi, sinusitis, ukuqwasha, myalgia, uhudo, ukuntuleka kwegazi emzimbeni, ukukhwehlela, ubuhlungu emuva , inzululwane, isicanucanu, vasculitis, edema, rhinitis. Uma uhlangabezana nanoma yiziphi lezi ukusabela, kufanele ngokushesha uthintane onguchwepheshe.

"Candesartan"

ekwakhiweni Okubukwe washayelwa amaphilisi kwezokuphatha ngomlomo. Kufanele ithathwe kanye noma kabili ngosuku kule esilinganayo kungakhathaliseki ukudla. Kufanele ulandele ngokucophelela izincomo lochwepheshe. Kubalulekile ukuba ayeke ukuthatha izidakamizwa ngisho noma uzizwa ungcono. Uma kungenjalo, singadambisa ukuphumelela izidakamizwa.

Lapho uyisebenzisa kufanele niqaphele ukuba yalezo ziguli abanesifo sikashukela, esingamahlalakhona kwezinso noma ukuchamisela ingane. Zonke lezi zifo kufanele aziswe ochwepheshe.

"Telmisartan"

Kubhekwe umuthi amuncwa umzimba kusuka pheshana emathunjini esikhathini kwetfulwe esifushane. It ingase ikhishwe kungakhathaliseki ukudla. Inkomba esemqoka sokusebenzisa nomfutho wegazi ophezulu. Ingxenye-ukuphila umuthi amahora angaphezu amabili. Umuthi isuselwe ngokusebenzisa amathumbu cishe zinjalo.

Okunqatshelwe thatha kubhekwe izidakamizwa ngesikhathi ekhulelwe noma ukuncelisa ibele.

Umuthi kungabangela lokhu okulandelayo side effects: ukuqwasha, isiyezi, isicanucanu diareyayu, ukucindezeleka, ubuhlungu besisu, pharyngitis, amawala, ukukhwehlela, myalgia, pheshana urinary nezifo, umfutho ophansi wegazi, ubuhlungu besifuba, palpitations, ukuntuleka kwegazi emzimbeni.

"Eprosartan"

Kubhekwe umuthi kufanele kuthathwe kanye ngosuku. Inani watusa kwezidakamizwa isicelo esisodwa kuba angu angamakhulu ayisithupha. Umthelela esiphezulu kufinyelelwa ngemva kwamasonto amabili kuya kwamathathu ukusetshenziswa. "Eprosartan" kungaba yingxenye yokwelapha edidiyele monotherapy Isakhi esiyinhloko.

Akunakusetshenziswa asikwazi kubhekwe ukusebenzisa izidakamizwa ngesikhathi lactation noma ukukhulelwa.

Iziphi izinkinga zokwelashwa kungenzeka uma usebenzisa "eprosartan"? Phakathi kwabo kukhona lokhu okulandelayo: ubuthakathaka, uhudo, isiyezi, ubuhlungu bekhanda, rhinitis, ukukhwehlela, iphika, edema, esifubeni ubuhlungu.

"Irbesartan"

izidakamizwa Okubukwe ezithathwe ngomlomo. Wayelethwa ngesikhathi esifushane amuncwa umzimba kusuka pheshana emathunjini. Ubuningi esiphezulu into egazini kwenzeka ngemva nje kwamahora ambalwa. Ukudla akuphazamisi kusebenta izidakamizwa.

Uma isiguli inikezwa hemodialysis, ke akuphazamisi lo mshini wezenzo "Irbesartan". Lezi zinto ethathwe umzimba womuntu ngu hemodialysis. Ngokufanayo, umuthi angamukela ngokuphepha iziguli isifo sokusha kobukhulu okuncane noma okusesilinganisweni.

Umuthi kumele kugwinywe ngaphandle ukuhlafuna. isicelo sayo ayidingi ukuba kuhlanganiswe ukudla. isiqalo kahle umthamo kubhekwa ngayikhulu namashumi ayisihlanu angu ngosuku. iziguli esezikhulile Sisikisela ukuqala ukwelashwa nge angu ayisikhombisa. Phakathi ukwelashwa, udokotela wakho anganquma ashintshe isilinganiso semithi oyidlayo (isib, izithelo zawo ngaphansi isimo enganele imiphumela zokwelapha emzimbeni). Kulokhu, isiguli kungase kudingeke ukuba uthathe angu angamakhulu amathathu izidakamizwa noma bayawushintsha izidakamizwa oyinhloko isimiso. Ngokwesibonelo, ukwelapha ngifundise ngesifo sikashukela ohlobo wesibili kanye nomfutho wegazi ophezulu Isikali kumele kancane kancane washintsha esuka ngayikhulu namashumi ayisihlanu angu usuku angu angamakhulu amathathu (okungukuthi inani nomuthi is ephumelela kunazo yokulawula nephropathy).

Zikhona izici ezithile isicelo sale izidakamizwa. Ngakho, iziguli iziyaluyalu ibhalansi uketshezi electrolyte, ngaphambi ukwelashwa ezinye izinhlobo zako kuyadingeka ukuqeda (hyponatremia).

Uma kukhona ukwephulwa umsebenzi izinso, ayokwelashwa lwemithi kubantu kungenzeka okufanayo sengathi kwakungekho inkinga enjalo. Kuyefana nasendleleni ukungasebenzi hepatic okuncane. Ngesikhathi esifanayo, lapho hemodialysis lemali sokuqala umuthi okumele kuyehla ngesigamu eqhathaniswa ezivamile futhi bakha angu ayisikhombisa nanhlanu ngelanga.

Ochwepheshe batusa ukusetshenziswa kwezidakamizwa kubhekwe kwabancane, njengoba hhayi kusungulwa njengoba kuphephile futhi kusebenza ngempumelelo kulonyaka iziguli.

"Irbesartan" ngokuqinile contraindicated ukusetshenziselwa izinhlelo abesifazane ngubani amthole umntwana, ngoba kuthinta ngqo inqubo wokukhula kwengane esiswini. Uma ukukhulelwa ngesikhathi yokwelapha zabo, zinyanga kumele isuswe ngokushesha. Kunconywa ukushintshela imikhiqizo okunye ngaphambi kokuqala ukuhlela sokukhulelwa. Okubukwe ukusetshenziswa kwezidakamizwa akuvunyelwe ngesikhathi ibele, njengoba kungekho ulwazi ngokuthi ngabe into ngobisi lwebele.

Efingqa

Gcina impilo yakho - duty siqu awo wonke umuntu. Futhi amadala yobudala, uma wenza umzamo owengeziwe ke kuyodingeka wenze. Nokho, abekho embonini yokwenziwa kwemithi has usizo olukhulu, njalo esebenza ukudala izidakamizwa kangcono futhi kuphumelele kangcono. Kuhlanganise kabanzi wokulwa nesifo senhliziyo okuxoxwe ngazo kulesi sihloko, angiotensin yokwamukela blocker 2. Izidakamizwa, uhlu okwakubekelwa ekhonjiwe futhi idingidwa kulesi sihloko, kufanele isetshenziswe futhi isetshenziswa uya khona udokotela ukuba khona ubani ujwayelene wamanje isimo lesiguli zempilo, futhi kuphela ngaphansi kophiko lwayo unomphela. Phakathi kwemithi enjalo isehlane "Losartan" "Eprosartan" "irbesartan" "telmisartan" "Valsartan" futhi "Candesartan". Linqume izidakamizwa kubhekwe kuphela kulezi zimo ezilandelayo: ebukhoneni umfutho wegazi ophakeme, isifo sezinso futhi senhliziyo.

Uma wayefisa, qala self-kubalulekile ukuqaphela ingozi ehambisana nakho. Okokuqala, uma usebenzisa izidakamizwa kubhekwe kubalulekile ukugcina ngokunembile umthamo kanye ngezinye izikhathi yayo kushintshwe kuye ngokuthi isimo samanje wonke umzimba wesiguli. Ukuze afeze zonke lezi izinqubo kuphela uchwepheshe kungaba kahle. Njengoba udokotela kuphela can ngaphansi luhlolo kanye imiphumela cwaningo nika ezifanele umthamo kanye nokwelashwa lwemithi yakha ngokunembile. Ngemva ukwelashwa ngokuphumelelayo kuphela uma kwenzeka ukuthi isiguli izolandela izincomo udokotela.

Ngakolunye uhlangothi, kubalulekile ngazo zonke izindlela neqhaza ekuthuthukiseni isimo zabo ezingokwenyama ngokwenza ngokuvumelana nemithetho ye indlela yokuphila enempilo. Iziguli kumele ulungise ubuthongo futhi sihlale siphapheme, ukuze silondoloze ukulinganisela amanzi, futhi ulungise yokudla (phela ukudla singenele, unganikezi umzimba izakhi ngokwanele kubalulekile, ngeke wakwazi ukukubuyisela ngokuphelele isigqi evamile).

Khetha imithi eliphezulu. Zinakekele futhi obathandayo. Hlala uphilile!