"Gleevec" (imatinib): the nozakwabo intengo. Lapho inzuzo ukuthenga Gleevec?

Antineoplastic (anti-isimila) ejenti "Glivec" kuyinto inhibitor amaprotheni tyrosine kinase. Isici esebenzayo zomuthi - imatinib - suppresses cell ayanda e isimila nendlala okuthiwa i imiphumela nokwahlukana elawulwa esitokisini imigqa (apoptosis), kuhlanganise wegazi emangqamuzaneni okuthiwa akhiwa in iziguli acute wegazi lymphoblastic ngefomu kanye nalabo abaphethwe ezingamahlalakhona wegazi myeloid e.

Kungani izidakamizwa ejwayelekile "Gleevec" intengo aphansi?

Ukuze uthenge nemithi ebalulekile akatholakalanga isiguli, kukhona ukukhiqizwa izidakamizwa ejwayelekile - izimali, ekhishwa uphawu izidakamizwa ubuchwepheshe futhi ube isithako efanayo esebenzayo. Umthelela kokuthola ejwayelekile kuyafana futhi intengo uhlale kufinyeleleke. Lokhu kungenxa yokuthi ukukhiqizwa yayo akudingi umakhi noma ukuthuthukiswa izindleko, akukho zindleko ukukhangisa nokuhlolwa.

izindlela IsiZulu "Gleevec", oluqanjwe ngokuqinile Indian Cipla Ltd. kuba, libito lalowo Imatib. Futhi ungakwazi ukuthenga it on the website WWW.ONKO24.COM., Ngesikhathi esifanayo sina ugcine on ukuthenga. Ngakho, capsule "Gleevec" intengo eRussia kugcinwa ngaphakathi ruble 73 000. Futhi intengo ejwayelekile esayithini okuthiwa mayelana ruble 7320. Ngiyavuma, umehluko kuyaphawuleka ngempela.

Isikali

Kodwa ngaphambi izidakamizwa ejwayelekile "Glivec" ukuthenga, kufanele uvumelane ukusetshenziswa kwalo nge onguchwepheshe abanolwazi ekwelapheni zabasiza abathile abanomdlavuza. Umthamo izindlela wathi incike Ihlahlubo isimo lesiguli.

Ngakho, endabeni ezingamahlalakhona myeloid wegazi (CML) kungenzeka eyabizwa ngokuthi mg 400 kanye 600 ngosuku. Futhi uma ayibangelwa yokwamukela neutropenia noma thrombocytopenia, umthamo wansuku zonke anda afinyelela ku-800 mg / usuku njengoba kudingeka. ukwanda okunjalo kungase kubangelwe izinkinga ukuqhubeka kwesifo kunoma yisiphi isigaba, futhi ukungabi khona umphumela olulindelekile ngemva kwezinyanga ezingu-3 Yiqiniso ukuze athole ukwelashwa.

Izici isicelo

Amaphilisi Abonayo "Gleevec" Kufanele bedakiwe kanye ngosuku aphuze amanzi amaningi. Ukuze ugweme iziyaluyalu wokugaya ukudla, ochwepheshe batusa ngokuthatha izidakamizwa ngokudla.

Uma isiguli inikezwa umthamo esiphezulu ejenti (800 mg), khona-ke kungcono wahlukanise 2 imithamo. Uma kudingeka, hlambulula izidakamizwa apple juice noma amanzi. Ukumiswa okuholela kufanele esiphuza ngokushesha ngemva nokulungiselela.

side effects

Imiphumela emibi ngokusebenzisa "Gleevec" imfundo izidakamizwa lapho kuhlongozwa kule iphepha, kunzima ngempela ukulinganisa, njengoba kukhona inqubo yokwelapha futhi izimpawu ezinhlobonhlobo ethize ukuze lesi sifo ecashile futhi izimpawu yemiphumela emibi yemithi ezithathwe ngesikhathi esifanayo.

Ukwahlulela ukubuyekezwa, "Glivec 'ebekezelele ngokubhekakade kahle nge kokubili abadala kanye nezingane. Kodwa imiphumela emibi isicelo yayo kwenzakala ikakhulukazi imnene ngokulinganisela.

Ngokuvamile kungabonwa:

• anaemia;
• isifo sohudo,
• isicanucanu, akhuthaza ukuba ukuhlanza;
• imisipha amajaqamba;
• ubuhlungu bemisipha kwendawo;
• ikhanda;
• ukuqubuka emzimbeni.

Izixwayiso

Ukwelashwa kwala magciwane kufanele kuhambisane ukuhlolwa igazi njalo, kanye ukulawula kokusebenza kwesibindi, isisindo somzimba kanye nemibandela emathunjini. ngokukhethekile kufanele inikezwa iziguli isifo senhliziyo kanye nezingane kusukela zokugcina ethola izidakamizwa Ingabangela ukuboshwa ukukhula.