I Amylase enzyme. Norm ezingeni umsebenzi wayo

Kwamakhemikhali kwegazi uqhutshwa ukucacisa umsebenzi enzyme. Enzyme kukhona amaprotheni molecule kusheshiswe ukugeleza emzimbeni zonke izinqubo kwamakhemikhali. Umuntu ngamunye izinhlobo eziningana enzyme, ngamunye okuyinto unomthwalo impendulo ngokuqinile kuchazwe eyodwa kuphela. Cabangela esinye enzyme esebenzayo enqubeni wokugaya ukudla - Amylase.

Kukhona izinhlobo ezintathu amylases: α-, β- futhi γ-Amylase, kodwa le ncazelo obujwayelekile umsebenzi α-Amylase. It is ekhiqizwa amanyikwe, nokuqukethwe kuyinto esiphezulu e ngamathe futhi juice amanyikwe. Lokhu-ke kusho ukuthi njengoba esebenzayo Amylase isikhungo aphume ashone calcium ion.

P gqwa S-uhlobo α-Amylase. ukuthi Esezishilo, futhi egazi noma omchamo Amylase samanje. Okuvamile - okuqukethwe 65% α-Amylase P-uthayiphe umchamo futhi mayelana 60% S-uhlobo α-Amylase egazini. Ngokuhamba izifundo kwamakhemikhali ukuze ugweme ukudideka futhi ugweme amaphutha, P-uhlobo alpha-Amylase, kwanqunywa ukuba ushayele diastase. Norma igazi Amylase ngoba umuntu ovamile ongenayo izinkinga zezempilo, kufanele kube khona abangaphezu kuka-200 U / L, kodwa umsebenzi umchamo diastase ongafinyelela afinyelela ku-1000 U / L.

Kufanele ukuthi ekunqumeni umsebenzi kungakanani Amylase, izinga linendima ebalulekile, ngoba iyiphi ukuphambuka kusuka lokho kungase kubonise ukuthi pancreatitis nanoma yiziphi ezinye izifo kwamanyikwe. Ngezinye izikhathi kungase kungabi kube nomphumela omuhle kakhulu cwaningo, sokunquma elingakanani umsebenzi igazi Amylase. Imithethonqubo womsebenzi enzyme kungenzeka kudlulwe. Lesi simo kuthiwa i hyperamylasemia. Isizathu ukuze kutholwe kwakho kungenzeka lezi zinto ezilandelayo:

• ekuqaleni pancreatitis acute;
• exacerbation amafomu njalo pancreatitis;
• khona kule amatshe amanyikwe , noma izimila;
• utshwala ukudakwa ;
• acute igciwane lohlobo, isibonelo, ezifana ingulube;
• ukhulela ethunjini.

Kukhona amacala lapho kuyinto evamile igazi Amylase, umchamo diastase elifanayo ngesikhathi esifanayo weqiwe. Lesi senzakalo ngokuthi giperamilazuriya. Kungaba ukuthuthukisa kulezi zimo:

• pancreatitis acute (diastase umsebenzi kunyuke izikhathi ayi-10-30);
• ahlukahlukene isifo sesibindi ukuvuvukala;
• cholecystitis;
• appendicitis acute;
• utshwala ukudakwa;
• wamathumbu isimiso;
• ekwelapheni izidakamizwa isisu ejenti sulfanilamide inzalo zemibuzo nezimpendulo morphine;
• emathunjini ukopha isilonda.

Kuyadingeka ukuthi umdlavuza pancreatic, pancreatitis okungamahlalakhona, kanye nokuthuthukiswa ingqikithi pancreatitis ngokuvamile abakwazi wandise ingxenye yawo ka Amylase. yokwenza evamile enzyme zingancishiswa. Ngokwesibonelo, kwehle umsebenzi umchamo diastase Kutholwe ngokuyinhloko ezifana nesifo ezinzima, amabhere lezinceku njengoba cystic fibrosis. yehlise amazinga umsebenzi α-Amylase egazini kungase kubangelwe ngomunye exacerbation okukhulu pancreatitis noma necrosis pancreatic.

Eqinisweni ezithakazelisayo: the Amylase likhona hhayi kuphela e kwamanyikwe, kodwa futhi nezinso isibindi. Nokho, izinga layo womsebenzi kunqunywa ngokuyinhloko khona izifo ezihlukahlukene pancreatic. Ukuze isifundo kuyakuba umchamo noma igazi umthambo esiswini esingenalutho ekuseni. Kumele kukhunjulwe ukuthi esikhathini esedlule awubalulekile ukudla okunamafutha kanye ukudla okunongwe ngemiphumela eqonde kakhulu. Ngokuvamile, eminyakeni yamuva cishe yonke laboratories yesimanje waqala ukusebenzisa izindlela enzymatic wokutadisha umsebenzi Amylase. izindlela ezinjalo kakhulu ethize futhi ngesikhathi esifanayo ngempela fast futhi kunembile.