"Losek CI": yokusetshenziswa. "Losek CI": ukuphathwa, ukubuyekezwa, izimpawu, contraindications

Ingabe uyasazi ukuthi, kulokho kwenza lokhu izidakamizwa ngokuthi "Losek CI"? Yokusetshenziswa, kanye izinkomba izidakamizwa uzobe achazwe kulo magazini. Ngaphezu kwalokho, sizokutshela kangakanani kubiza, wathi izindlela, uma kwadingeka iyiphi analogue kanye contraindications, yini imiphumela engemihle okuyokwenzeka ngemva kokuphathwa, nokuningi.

Ukwakheka, emabhokisini futhi ifomu zomuthi

Uyini elaphe "Losek CI"? Yokusetshenziswa usitshela ukuthi lokhu izidakamizwa itholakala kuphela ifomu tablet. I asebenzayo isici nomuthi izenzo omeprazole (10 40 noma 20 mg). Futhi amaphilisi zihlanganisa kanye izithako asizayo: monostearate glyceryl, MCC, hydroxypropylmethylcellulose, hydroxypropylcellulose, magnesium stearate, ushukela, methacrylic acid, talc, upharafini, triethyl citrate, polyethylene glycol, ama-titanium dioxide, polysorbate, yensimbi oxide, polyvinylpyrrolidone crosslinked kanye sodium stearyl fumarate .

Ukuthengwa nomuthi ingahle amabhodlela 14, 7 noma 28 amaphilisi (10 40 noma 20 mg) zafakwa ebhokisini amakhadibhodi.

pharmacodynamics

Kanjani lesi sidakamizwa "Losek CI"? Yokusetshenziswa lithi izidakamizwa esebenzayo kuyinto inhibitor ka H + -K + -ATPase. Ngaphezu kwalokho, sihlobana ejenti anti-isilonda. umenzeli asebenzayo kuyinto base ababuthakathaka. It is bagxila kule imvelo acid kwamaseli parietal we mucosa esiswini, isebenze futhi ezivimbela futha proton.

Umthelela omeprazole ku inqubo echazwe kuyinto umthamo nasekuthengeni. A nomuthi uyakwazi ukuhlinzeka okusithiyayo kuyaphumelela of basal kwavusa acid uketshezi kungakhathaleli isici ukuvuselela.

Ukusebenza ngomhla ka-uketshezi of juice esiswini

Nge nomuthi temlomo nsuku zonke "Losek CI", intengo ozokwethulwa kancane okwengeziwe, inikeza okusithiyayo ngempumelelo futhi okusheshayo nobusuku nemini uketshezi of hydrochloric acid. Okukhulu kunakho nomphumela oqabulayo siyenzeka ngaphakathi 4 izinsuku ukwelashwa. Abantu nge isilonda 12 duodenal isilonda 20 mg zomuthi kubangela ukuncipha kancane angu-24-asidi esiswini hhayi ngaphansi kuka-80%. Kufanele kuqashelwe ukuthi le umthamo nomuthi uyakwazi silondoloze ulimu intragastric asidi ezingeni pH> 3. Lo mphumela kuthathe amahora 17.

Ithonya Helicobacter pylori

Kanjani ngempumelelo ethathela wathi amagciwane imithi "Losek CI"? Regulations lebhalwe izidakamizwa, uthi omeprazole kunomphumela amagciwane phezulu Helicobacter pylori. Ukususwa amagciwane ngesikhathi isicelo kusho lihambisana elwa ne-webhaktheriya kuhambisana ukuqedwa sasivumela okusheshayo zonke izimpawu, kanye ngezinga eliphezulu sokuphulukiswa mucosa ethintekile ipheshana wokugaya ukudla. Ngaphezu kwalokho, le ndlela yokwelapha ikhuthaza eside ukuthethelelwa isifo emathunjini, okuyinto kwehlisa amathuba ukopha yansukuzonke.

Ezinye izimpahla zomuthi

Yini nezinye izakhiwo babe ukulungiselela ezifana "Losek CI"? ochwepheshe lezivakashi liyasho ukuthi iziguli njalo futhi isikhathi eside, thatha imithi ukuthi ukunciphisa uketshezi we nezindlala we ipheshana wokugaya ukudla, ngokuvamile baphawula izinhlumba yezindlala esiswini. Njengomthetho, bona awayona ingozi futhi zinyamalale bebodwa.

Ukwehlisa hydrochloric acid uketshezi esiswini ikhuthaza microflora evamile emathunjini. Nokho, lokhu kungase kuholele ekubeni ukwanda kancane ingozi izifo nokuthuthukisa.

Ngo abadala kanye nezingane, ukungenisa eside izimali, ukwanda inani lamaseli enterochromaffin uyalandelwa.

Phakathi ukwelashwa nge lokuhlushwa omeprazole ka gastrin egazini kakhulu anda.

Pharmacokinetics

It is angena imithi egazini "Losek CI"? Yokusetshenziswa ugomela ngokuthi ukumuncwa omeprazole kwenzeka emathunjini amancane (kungakapheli amahora 4-6). Sakusihlwa ngosuku bioavailability efana ayiphazamiseki. Ngemva kokuphathwa temlomo ke imayelana 60%.

Umuthi is akheka esibindini ngokuphelele. Ingxenye-ukuphila imayelana 30-80 imizuzu. Cishe ama-80% we ketshezi esebenzayo excreted njengoba metabolites ngu izinso, okusele kanye indle.

ubufakazi

Tablets "Losek CI" ezinqunyiwe lokuchezuka ezilandelayo:

• isisu isilonda;
• Reflux esophagitis;
• isilonda 12 isilonda duodenal;
• ukuguguleka emathunjini kubangelwa ama-NSAID;
• wokuqeda Helicobacter pylori;
• dyspepsia, okuyinto lihlotshaniswa ne-asidi eningi;
• gastroesophageal Reflux isifo (lingaze);
• Zollinger-Ellison syndrome.

Izimo

Ukulungiselela "Losek CI" ayikwazi engabelwe hypersensitivity lesiguli omeprazole kanye benzimidazoles ukufaka endaweni noma nezinye izithako ukuthi ayingxenye izidakamizwa.

Kufanele kuqashelwe ukuthi le izidakamizwa ezinqunyiwe ngokuqapha ebukhoneni abantu izici ezifana nokuguqulwa kwesisindo, dysphagia, ukuhlanza njalo nokuhlanza kwegazi. Ngaphezu kwalokho, e isilonda esiswini (noma isifo okusolwa) kufanele akhiphe khona isimila esibulalayo. Lokhu kungenxa yokuthi ukwelashwa nge omeprazole kalula imaski ngezimpawu alibale uphethwe yini.

Indlela ukuthatha imithi "Losek CI" (20 mg)?

Kulaba izimali kumele kuthathwe ngomlomo ekuseni. Umuthi kumele kugwinywe wonke ngamanzi. Umuthi akufanele ukusiqeda noma ukuhlafuna.

Izibhebhe avunyelwe ukuncibilikisa uketshezi kancane acid noma amanzi (isb, neziphuzo zezithelo). Nokho, ikhambi okuholela ziphele ngaphansi kwehora.

Lapho Reflux ngomphimbo, esiswini kanye isilonda duodenal a-ukulungiselela 12 ezinqunyiwe 20 mg kanye ngelanga. Lapho Reflux esophagitis umthamo lenyuke kabili.

Isikhathi ekwelapheni isilonda amasonto 2-4 at Reflux esophagitis - amasonto 4, futhi gastroesophageal Reflux - amasonto 4-8. Ukuvimbela uyahluleka uma elwa nokuphuza izilonda futhi Reflux oesophagitis ingase yabelwe eside ethola izidakamizwa umthamo 10 mg.

side effects

Medicine "Losek CI" analogs izidakamizwa kungadala imiphumela emibi. Okuvame kakhulu yilezi ezilandelayo izimo zokucabanga okubangelwa isifo: ikhanda, ukubuyisa, lesisu ubuhlungu, ukuqunjelwa nohudo, ukucanuzela kwenhliziyo nokuhlanza.

Ukuze ukungasebenzisi imiphumela emibi ibandakanya dermatitis, isifuba, isiyezi, ukulunywa, paresthesia, ukuqubuka, ukucobeka, ukozela, msebenzi omkhulukazi enzyme isibindi, nokuqwasha.

Kunalokho ezingavamile seziguli ezithola omeprazole kuphakama hypersensitivity ukusabela (isib ukushaqeka anaphylactic, imfiva, anaphylaxis, edema angioneurotic), kanye bronchospasm, isifo sokusha kwesibindi, ukuba buthakathaka kwezicubu, ukwehluleka hepatic, leukopenia, encephalopathy, arthralgia, ukucindezeleka, myalgia, pancytopenia, thrombocytopenia, ukuyaluza, agranulocytosis, nomlomo owomile, hyponatremia, candidiasis emathunjini, ubudlova, photosensitivity, ukudideka kanye esilufifi umbono, ukuhhema, ukujuluka, ukunambitheka nasiphazamiso, Periph edema -geometric, stomatitis, nephritis interstitial, Alopecia, gynecomastia, erythema multiforme, nesifo ngesibonakhulu, Stevens-Johnson syndrome ne anobuthi epidermal necrolysis.

Kakhulu akuvamile waphawula hypocalcemia, hypomagnesemia, hypokalemia futhi hypomagnesemia.

Medicine "Losek CI": intengo kanye analogue

Kuqhathaniswa izidakamizwa ezifanayo, intengo izimali impela high. Ngakho-ke, izibhebhe 14 kuzodingeka akhokhe ruble Russian mayelana 250. Uma ucabangela ekuphathweni isikhathi eside nomuthi (2 kuya kwayisi-8), ukuphathwa abiza kakhulu kubo.

I esikhundleni lesi sidakamizwa "Losek CI"? Analogs ithuluzi babe nekusebenta efanayo. Nokho, ngaphambi kokuzisebenzisa, qiniseka bonana nodokotela wakho kuqala.

Ngakho, esikhundleni imithi "Losek CI" angase abe abantu imithi ezilandelayo: "Acre Omeprazole", "Vero omeprazole", "Tsisagast", "Gastrozol", "Helol", "Demeprazol", "Helitsid", "Zhelkizol", "Ultop "" Zerotsid "," Ulkozol "," Zolser "," Ulzol "," Krismel, "" I sopranos, "" Losek "," Romesek "," Omez "," Promez "," Omez D "," Pleom- 20 "," Omez Insta "," Peptikum "," Omezol "," Otsid "," Omekaps "," Ortanol "" Omeprazole "" Omitoks "" Omeprazole Richter, "" Omipiks "" Omeprazole STADA " "Omizak", "Omeprazole Zentiva", "Omefez", "Sandoz Omeprazole", "Omeprus", "Omeprazole-OBL", "Omeprazole-FPO" "Omeprazol-Teva", "Omeprazole-akos".

nobufakazi

Yini iziguli ekushoyo izidakamizwa "Losek CI"? Amazwana ngalokhu luhlobo akhayo kakhulu. Ngokusho kwalabo abake wathi nomuthi, it is impela kahle ususa zonke izimpawu asidi of juice esiswini. Futhi umphumela uba obonakalayo cishe ngokushesha ngemva kokuba ukungenisa amaphilisi (1-2 amahora).

Ibhekwa izindlela ezisetshenziselwa isilungulela kanye ukuncinza ngemuva breastbone.

Naphezu kahle eliphezulu zomuthi, iziguli eziningi akhononde ukuthi ngemva kokuqedwa wavuma ukungakhululeki wabuya. Kulokhu, odokotela batusa ukuba aqhube olunzulu ukwelashwa kanye imithi ukusetshenziswa okungenani amaviki amane.