Pancytopenia - isimo sokugembula lapho incipha egazini afundwa tonkhe tincenye kwengoma. Izimbangela, izimpawu, ukwelashwa

Yini ngokwezemvelo ukuthuthukiswa lesi sifo emzimbeni kubangela ushintsho ukusebenza kusukela egazini neuropathy. Nokho, kukhona eziningi pathologies okuyiwona izinguquko zinjalo main isici emtholampilo. Pancytopenia - ingenye izinqubo sokugembula kohlelo hematopoietic, okuyinto kuchazwa ngokuthi isifo ezimele, noma kungenzeka kubonisa ezinye concomitant nosological.

imiqondo Jikelele

Lesi sifo akusilo ezivamile, ngakho abantu abaningi abawazi into enjalo. Pancytopenia - esimweni ukuntula kwamangqamuzana egazi, ukuthuthukiswa zazo kubangelwa kwezinso ekwakhekeni kwamangqamuzana egazi eyandulela at the stage of hematopoiesis. yehlise amazinga igazi amangqamuzana abomvu, amangqamuzana amhlophe egazi ne-platelet ngenxa yokuthi amaseli stem ayikwazi ngokwanele ukusebenza.

Lesi sifo eba amafomu amabili:

• idiopathic, kubangelwa izici yangaphakathi;
• yesibili, okuyinto mthelela oseqadi.

Isimo sokugembula cishe ngo-50% amacala eba sokuhlasela kwamasosha omzimba uhlobo. Okusho ukuthi, umzimba elwa yedwa egazi yakho ngephutha kubo for amanxusa akwamanye amazwe. ifomu Idiopathic kungaba ivukele ukunamathela ezengeziwe isici zangaphandle ukuthi ngesivinini umphumela ezingezinhle.

Pancytopenia - isifo kungenziwa ngofuzo, ukuthuthukisa ngesikhathi lapho ingane esibelethweni. Ingane izalwa kakade iziyaluyalu kwezitho igazi-ukwakha. Kungaba azalwa naso futhi umnkantsha hypoplasia, ukuze isistimu akakwazi ukubhekana nemisebenzi yabo.

Etiology lesi sifo futhi engcupheni

Phakathi kwezimbangela eziyinhloko ukuthuthukiswa zezifo ukuguquka kwezakhi zofuzo, ukusetshenziswa eside izidakamizwa, enemisebe noma imiphumela anobuthi. Nokho, ifomu Idiopathic libhekene yokuthi imbangela akukwazi ukusungulwa, kwaba nezigameko lesi sifo ngemva ukuzalwa.

Ukusungula izizathu kubalulekile ngoba umphumela omuhle. Ukuyeka ithonya zangaphandle ezimbi kule isifo - 50% impumelelo.

Ngaphezu sezizathu ezinkulu kukhona izinto ezimbalwa ukuthi bafake isandla ekuthuthukiseni we zokugula:

• Sebenza benzene noma i-arsenic,
• anaemia Fanconi;
• ubunjalo yegciwane ukutheleleka;
• ngelashwa nangemithi;
• antibiotic immunosuppressants;
• izifo sokuhlasela kwamasosha omzimba ezifana omzimba izicubu erythematosus;
• radiotherapy.

anaemia Fanconi - yezimbangela etiological ka pancytopenia. Kutfutfukisa on isizinda anomalies azalwa naso kubhekwa i autosomal isifo esikhubazayo. Isifo sokulahlekelwa yigazi libhekene khona yokulimala izingxenye amaprotheni obhekene ukulungisa i-DNA ne-chromosome friability.

Lwasemtholampilo isithombe lesi sifo

isimo sokugembula kuzibonakalisa ngesimo syndromes ezintathu. Ngayinye yalezi zici isici ukunciphisa isibalo uhlobo olulodwa kwamangqamuzana egazi. Leukopenia kuboniswa isithombe sepsis oyingozi futhi ukuvela izinqubo isilonda-necrotic kwesikhumba futhi nolwelwesi lwamafinyila.

Erythropenia nokwehlisa olukhulu endleleni elithwala umoya-mpilo avuse ukuthuthukiswa izimpawu igazi. Lesi simo libhekene:

• paleness zesikhumba integument;
• izimpukane phambi kwamehlo akhe ;
• isiyezi;
• tinnitus;
• ubuthakathaka kanye ukukhathala;
• ubuthakathaka.

Iziguli esekhala iphika inhliziyo palpitations. Auscultation ukunquma bengakhulumi inhliziyo amathoni, nokububula systolic phezu bonke ubuso projection inhliziyo, umsindo phezulu vein jugular. Eziwohlokayo kwesimiso lesiguli kubangela izinguquko electrocardiogram, okuyinto ukhombise ukuthuthukiswa ephethwe yisifo senhliziyo.

Thrombocytopenia livezwa njalo ukopha (epistaxis, emathunjini, lesizalo), ukopha izinsini, ukubukeka petechiae nokopha esikhumbeni. izimpawu olunamandla zesifo agcinwa isikhathi esingangenyanga futhi ngokuvamile iholela ekufeni. pancytopenia Okungalapheki avunyelwe ngconywana futhi izimpawu kancane evelele

lesi sifo ubhekwa ngoba sinzima kakhulu. Pancytopenia, okuyinto yezinkinga kuvamile kubantu abadala, ephelezelwa ukubukeka izifo kanye ukopha.

izinyathelo zokuxilonga

Icala lokuqala kudinga ngokukudlulisela ukuhlolwa onguchwepheshe, iqoqo umlando wokuphila isiguli. Ngaphezu kwalokho esimisiwe CBC. Endabeni lezi yizinkomba zingabonisa on ukuthuthukisa pancytopenia nokuziphatha sezithatha izinyathelo ezinqala zokuxilonga:

• leukocyte <2 x 109 / l;
• platelet <150 x 109 / L;
• erythrocyte <3.5 x 109 / l.

Inikezwe cwaningo wokubhoboza umnkantsha, okuyinto uchaza khona amaseli angavamile kanye myelokaryocytes. Kunqunywa khona okuthile okungahambi kahle emzimbeni, kuhlanganise umnkantsha hypoplasia. Futhi aphethwe amasampula hemolytic.

ukwelashwa pancytopenia

izinyathelo zokwelapha kuxhomeke esimweni yomtholampilo, isimo lesiguli kanye isici etiological ezibangele isifo. Izindlela ukwelashwa ezilandelayo ingasetshenziswa:

• Igazi, ukulinganisela phakathi kwemithwalo yakho ibhalansi izakhi ifomu.
• Ukufakelwa of umnkantsha noma ama-stem cell. Ngokuvamile kwenziwa ezigulini esemncane phakathi.
• Endabeni pancytopenia sokuhlasela kwamasosha omzimba iqondiswa isicelo immunosuppressant "Cytoxan", "Methylprednisolone," "Neoral", "Sandimun".
• Kusho inkanuko umnkantsha ukusebenza - "Neupogen", "Neulasta", "Procrit", "Leukin".

izitshalo izidakamizwa

Isakhiwo yokwelapha isifo kuhlanganisa ukusebenzisa imithi engamakhambi. Izinga abomvu egazi athwala umoya-mpilo futhi engase ibuzwe ngosizo amajikijolo. zezinkambi Eqiniswe zenziwa ngesisekelo ash, currants black, rose okhalweni, ama-strawberry, amajikijolo, ibhilikotsi. Bamba ithambo turnips ocebile, gooseberries, cherry futhi amagilebhisi, ukudla ezazingathandi kuphela silinganise ibhalansi kwamangqamuzana egazi, kodwa futhi ukuqinisa amasosha omzimba.

Inani izindlela abantu ekwelapheni pancytopenia yakhiwa uju. It is kuhlanganiswe kule mikhiqizo:

• nge obomvu kanjalo newayini Aloe;
• nesweli;
• oats;
• lemon, amabhilikosi omisiwe, omisiwe asithena kanye walnuts.

Namathisela kakhulu infusions kanye Iziphungo yamakhambi okwelapha sembabazane sembabazane, birch, utshani sage, clover, dandelion, ama-orchid, clover, nokunye okufana nokolweni.

isiphetho

Pancytopenia - ukugula okungathí sina, okuyinto kulingana lesi sifo sibulale. umphumela omuhle incike kobukhulu izimpawu zokwelapha, amafomu kanye izigaba yentuthuko lapho ukwelashwa uqalise. isifo ezinjalo kulula ukuvimbela kunokuba ikhambi.

Ukuhlolwa yonyaka yezokwelapha sabantu kunomthelela ukuhlonza isimo sokugembula kusaqalwa. Ikakhulukazi le osebenza ku izindlela laboratory luhlolo.