Somogyi Syndrome noma syndrome ezingamahlalakhona insulin ukweqisa izidakamizwa (SKHPI): izimpawu, uphethwe, ukuphathwa

Somogyi Syndrome - isifo ezingavamile kodwa kunganakekile, ikakhulukazi abantu abadumile abaphethwe isifo sikashukela. ingaze kanjani nokuthi ingelapheka?

Umqondo syndrome Somogyi

Ngo sikashukela kudinga ukubala lesifanele umthamo we-insulin, kodwa ngokuvamile kungaba nzima ukwenza, okuyinto igcwele ukuxakeka. Umphumela uba njalo izidakamizwa ukweqisa izidakamizwa Somogyi syndrome. Ngamanye amazwi, kuba syndrome ezingamahlalakhona insulin yokweqisa. nososayensi waseMelika uMichael Somogyi wafunda lesi simanga ngo-1959 futhi waphetha ngokuthi edonsa ngemithamo ngokweqile we ketshezi kuphakamisa kahle kungakhuphula izinga likashukela - ukwehla kwamazinga igazi glucose. Lokhu kuholela ezishukumisayo hormone futhi impendulo kontrinsulinovyh - Hyperglycemia Rebound (ukwanda igazi glucose ezingeni).

It kuvela ukuthi nganoma isiphi isikhathi ezingeni igazi insulini ingaphezu kwe ofiselekayo, okuyinto kwelinye icala ehola kahle kungakhuphula izinga likashukela, kanti kwesinye - ukuze ukudla. A ukukhishwa kwama-hormone ebangela unomphela senhliziyo kontrinsulinovyh e igazi glucose ezingeni, okubangela ukugeleza engazinzile sikashukela, futhi kungaholela ketonuria (acetone e umchamo) kanye ketoacidosis (inkinga sikashukela).

amaqiniso angokomlando

Insulin yaqale esetshenziswa ngempumelelo ngo-1922, ngemva kwalokho ngaqala ukufunda naye olunzulu nemiphumela yayo umzimba, kwenziwe ucwaningo on izilwane nabantu. Ososayensi bathole ukuthi ebulilini izidakamizwa izilwane kubangele ukushaqeka hypoglycemic, ngokuvamile okuholela ekufeni. Kwavezwa inqwaba imiphumela anobuthi le-hormone emzimbeni. Kuleyo minyaka yokuqala, umuthi yasetshenziswa ekwelapheni iziguli ene-anorexia ukuze andise isisindo somzimba wabo. Lokhu kwaholela ezinguqukweni njalo amazinga igazi glucose, ukuhluka kusuka kahle kungakhuphula izinga likashukela ukuze Hyperglycemia. Lapho beqeda indlela yokwelashwa isiguli izibonakaliso sikashukela. A nomphumela okufanayo okwenzeka ngo-wezifo zengqondo ngokuba nokwelashwa kweziguli bayasangana "insulini uthuthumele". Iphethini phakathi ukwanda umthamo kanye ukwandisa insulini yabonisa glycemia futhi ekwelapheni isifo sikashukela. Lesi simo esiyingqayizivele sibangelwa liye laziwa esikhathini esizayo njengoba Somogyi syndrome.

izimpawu

Njengoba self-ukuqonda ukuthi umzimba echayeke ukweqisa izidakamizwa ezingamahlalakhona insulin? Somogyi syndrome livezwa zimpawu:

• kukhona ukuwohloka jikelele impilo, kukhona ubuthakathaka,
• ikhanda okungazelelwe, isiyezi, ezingasetshenziswa kakhulu angalandeli engayitholi wezokudla carbohydrate,
• ubuthongo okhathazekile, iba ukukhathazeka futhi kokuya ensimini, ngokuvamile amaphupho amabi,
• kunomuzwa njalo zokukhathala, ukozela,
• uvuke ekuseni nzima, abantu bazizwa bephelelwa amandla,
• ingavela angaboni kahle ngesimo kwakukhuphuka inkungu phambi kwamehlo akhe, umgubuzelo noma ukubanika izindawo elikhanyayo,
• ukushintshashintsha kwemizwelo, amehlo ngokuvamile ohlangothini ezimbi,
• isifiso sokudla kakhulu, isisindo somzimba.

izimpawu enjalo iyashaqisa insimbi, kodwa akumele babe isizathu esisobala uphethwe, njengoba izimpawu izifo eziningi. A ophelele izinqubo ezenzeka emzimbeni usukela ngosizo ukuhlolwa.

ukuhlola

Sifo "Somogyi syndrome" ukusiza lezi zimpawu yilezi:

• ukubukeka ketone emizimbeni (acetone) emchamweni,
• abukhali futhi ngokushesha izinkomba iyehla iyenyuka glucose ezingeni kusukela phansi kuya phezulu futhi emuva usuku lonke,
• kahle kungakhuphula izinga likashukela obala noma ngokuphelele,
• glucose ngcono imikhuhlane,
• sikashukela siba sibi nge okwandisa ngemithamo insulin futhi kuthuthukisa nge ukwehla.

Somogyi syndrome uphethwe ezimweni eziningi kunzima ngisho nochwepheshe, akusho ukuthi i-kokubonisana endocrinology anganika Imiphumela lesifanele ngokushesha. Lokhu kungenxa yokuthi izimpawu isiguli neziyaluyalu ezenzeka emzimbeni wakhe, kungaba i-signal njengenhlangano overabundance insulin, futhi kusilela yayo. Isithombe emitholampilo kulezi izinqubo ayafana, ukweqisa izidakamizwa ezingamahlalakhona kungatholakala kuphela ngaphansi ebhekiwe kanye cwaningo onekhono ngokucophelela ihlaziya. Sifo kusekelwe ezintweni ezifana isethulo ejwayelekile yomtholampilo, njalo umbuso hypoglycemic, a high blood glucose iyehla iyenyuka.

ukuxilongwa umehluko

Somogyi e sitholakele lesi sifo udidekile kalula izenzo lo mkhuba "entathakusa", njengoba izimpawu zalezi pathologies amabili ayafana yini. Nokho, kunomehluko obalulekile. Lo mkhuba "entathakusa" litholakala hhayi kuphela iziguli sikashukela, kodwa futhi abantu abayimiqemane, wabonisa Hyperglycemia entathakusa. Lokhu kungenxa ukuntula amazinga insulin basal ngenxa ukubhujiswa okusheshayo isibindi noma ukukhululwa sithuthukiswe yakhe i-hormone contrainsular ekuseni. Ngokungafani Somogyi syndrome, ukubonakaliswa zalesi simo akuyona kwandulelwe kahle kungakhuphula izinga likashukela. Ukuze ithole ukuxilongwa okufanele kuyadingeka ukwazi igazi glucose ezingeni ezimbili kuya ekuseni, in iziguli esingelapheki syndrome ukweqisa izidakamizwa ke lehliselwa, futhi isiguli Hyperglycemia kokusa akashintshi. Yokwelapha lezi zifo kuphambene: ecaleni lokuqala, umthamo insulin encishisiwe ke yesibili - ukwandisa.

Izici sikashukela syndrome Somogyi

Inhlanganisela sikashukela sifo of ukweqisa izidakamizwa ezingamahlalakhona insulin (SKHPI) kunikeza nethonya elilimazayo, lesi sifo singumbulali abukhuni. Against isizinda njalo ethola ngemithamo ngokweqile kahle kungakhuphula izinga likashukela kuba ifomu esicashile. Somogyi syndrome sikashukela kubonakala isimo jikelele isiguli, futhi ukuziphatha kwakhe.

ukuguquguquka ngokushesha kwemizwa ngaphandle isizathu - into njalo nokugula okunjalo. Lapho izinto zokuzilibazisa sifundo noma yiliphi ibhizinisi umdlalo emva kwesikhashana indoda ngokuzumayo ilahlekelwa isithakazelo konke kwenzekani, kuba evilaphayo kanye bengenandaba, ngabandayo yizimo zangaphandle. Ngezinye izikhathi yokucasukela unmotivated noma ukucasuka singenzeka. Isikhathi esining impela, kukhona isifiso yanda e isiguli, kodwa, naphezu kwalokhu, ngezinye izikhathi kukhona isimo sengqondo esingaqondile ukuze ukudla, le ndoda iyenqaba ukudla. Lezi izimpawu zenzeka 35% eziguli. izikhalazo Okuningi ezivamile zihlanganisa ukuhlaselwa ubuthakathaka, isiyezi, ubuhlungu bekhanda, ukuphazamiseka kokulala. Ezinye uqaphele ongaboni okuzumayo esifushane (ngesimo iveli phambi kwamehlo noma elikhanyayo "izimpukane").

ukwelashwa

Ukwelashwa yalesi sifo kuhilela Somogyi ukubala lesifanele insulin Ukweqiwa. Ngenxa yale njongo, lemali iqondiswa kumele kushintshwe, kuyehla by 10-20% ngaphansi observation esiqinile isiguli. isikhathi esingakanani iphathwa Somogyi syndrome? Kuye izinkomba ngabanye amasu ukulungiswa ezahlukene ezisetshenziswa - fast and kancane. Okokuqala olwenziwa past amasonto amabili, wesibili kuthatha izinyanga 2-3.

Uma uthi nhlá, UMUNTU angase acabange ukuthi ukuncipha insulini umthamo kuzoholela ukunyamalala ngalesi sifo, kodwa akuyona. ukunciphisa nje in inani izidakamizwa iqondiswa ingakuthuthukisi Yiqiniso sikashukela, ukwelapha kumelwe abe eziyinkimbinkimbi. Kuthinta Ukudla (kulesetayelekile inani carbohydrate babambeke ukudla), umzimba. Insulin iqondiswa ngaphambi kokudla. Kuphela indlela olunzulu kungaba nemiphumela emihle ekulweni sifo Somogyi.

ukuba nombono ongafani ngeke

Ukuthola esifike syndrome ezingamahlalakhona insulin ukweqisa izidakamizwa has izibikezelo omuhle. Kubalulekile nokuzinakekela, amasignali zomzimba, noma yiziphi izinguquko isimo Ukuwohloka wezempilo ngokushesha kudokotela uyofuna icebiso, isibonelo, i- Centre of Endocrinology ngesikhathi zezemfundo (eMoscow). I umphumela omuhle ekwelapheni indima eziyisisekelo eyadlalwa bomsebenzi kanye nentshisekelo nolwazi olunzulu udokotela. Lapho akubonakali syndrome izibikezelo okungekuhle: ukweqisa izidakamizwa okuqhubekayo insulini izosebenza kuphela isimo sibe sibi ngezimo zesiguli, isifo sikashukela siya siba sibi kakhulu.

zokuvimbela

Main SKHPI zokuvimbela izindawo zihlanganisa iqoqo izinyathelo.

• Ngo sikashukela kufanele ngokuqinile banamathela Ukudla kahle ukuze kuhambisane nesineke futhi kuqinisekisa ukunxeshezelwa carbohydrate umzimba. Umuntu kufanele sihlele ukudla kwakho, bakwazi ukubala inani ukudla carbohydrate kudliwe, ikhiqiza i esikhundleni ezanele komkhiqizo uma kunesidingo.
• yokwelapha insulin iqhutshwa ngemithamo adingekayo isiguli esithile. umsebenzi udokotela - uma kudingekile ukwenza ukulungiswa, isiguli - ukuqapha nokudlondlobala umzimba.
• umsebenzi njalo kubalulekile ukuze iziguli sikashukela, ikakhulukazi uma isiguli sifuna sedentary noma umsebenzi Hlala phansi.
• zokuqapha njalo lesi sifo, i kokubonisana endocrinology ku-schedule ngamunye futhi njengoba kudingeka.
• ukuhlolwa lolwenetisako isimo umzimba, ezempilo, ukuthola okusheshayo izimpawu asolisayo.
• Ukudalwa izimo ukuzithiba ekuphileni kwabo kwansuku zonke, isifundo iziguli kanye namalungu omndeni izimiso ukuzithiba.

Somogyi syndrome ezinganeni

Izingane abaphethwe isifo sikashukela, abakwazi njalo ukulandela izinguquko isimo umzimba, ngokuvamile lokhu akunakwenzeka, ngakho-ke, ukulawula Yiqiniso yokugula - abakhathalelayo nabanokwethenjelwa. aqaphelisise umntwana ilele, njengoba insulin ngokuyinhloko ebusuku, futhi ukuziphatha kwengane ongamtshela eziningi. Lapho okubonakalisa syndrome ukulala ke kuba matasa futhi eligcizelela ukubukeka kwangaphandle, ephelezelwa ukuphefumula ezinomsindo. Ingane ingaba ukuthethisa noma ukhale elele ngenxa obumnandi. Awakening esindayo, ngokushesha ngemuva kokuba kwenzeke ukudideka.

Zonke lokhu kubonakaliswa - uphawu isimo hypoglycemic. Lonke usuku umntwana ubesesimweni isimo flaccid, nguye ezingezwakali, ukuhluthuka, akakuthandi imidlalo noma izifundo. Nokunganakwa kungenzeka ngokuzumayo, ngaphandle isizathu, ngokuhamba kweseshini. nokuqubuka njalo sonya unmotivated, ukushintshashintsha kwemizwelo kukhona ezingalindelekile. Ngokuvamile, izingane sifo isifo sokudangala. Ukwelashwa Kwenziwa isimiso efanayo ukuthi abantu abadala. Endocrinology Center ku Academic, isibonelo, kusiza izingane zibhekane nokusuke sifo Somogyi.