Umuthi 'Pregnil ": ukubuyekezwa, imiyalelo

abesifazane abaningi kakhulu abahlushwa ukungatholi abantwana. Siyabonga emithini zanamuhla ukuxazulula inkinga, ukuzizwa injabulo umama. "Pregnil" kungenziwa ngokuthi omunye imikhiqizo ethandwa kakhulu futhi kungase kutholakale. Izibuyekezo kwesokunxele cishe zonke nesineke bajabule.

Ifomula kanye ukukhululwa izidakamizwa

Lokhu isakhi sokuzakhela human chorionic gonadotropin. Umuthi is injected phansi kwesikhumba futhi intramuscularly. umkhiqizo Leofilizat kuyinto mhlophe. Kuye lenqwaba kuhlanganisa umfuma equkethe kuphela. Yena umbala esobala futhi kungekho nto enemibala emihle. izidakamizwa Main 'wesimo Pregnil' - kuyinto human chorionic gonadotropin. izingxenye Ukusekela kukhona magnesium hydrogenphosphate, sodium carmellose, mannitol, sodium digitrofosfat.

I kuphela yakhiwa isixazululo isotonic of sodium chloride. izidakamizwa Itholakala umthamo 2 ml. Leli bhokisi linezimpendulo izitsha eziyisikhombisa ezintathu ndaba ezomile futhi inani elifanayo izitsha eziyisikhombisa ukuncibilikisa izidakamizwa "Pregnil". Izibuyekezo abonisa ukuthi ukuze kufezwe sokukhulelwa olufunayo etholwe 60% amacala ngemuva ezelashwayo.

imiphumela kwemithi

Medicine "Pregnil" iqukethe human chorionic gonadotropin. It has ngezinga eliphezulu ukufana isenzo saka-luteinizing hormone. Le into kubalulekile nokukhula okuvamile kanye nokuvuthwa of gametes owesilisa nowesifazane. LH futhi udinga ukudala hormone ocansini. Kuyathokozisa ewusizo kokubili besifazane kanye nabamele ubulili namandla. I bubuhle ubulili izidakamizwa "Pregnil" ingena esikhundleni imfundo maphakathi nawo-umjikelezo we endogenous luteinizing hormone, ukusiza ukuqedela ukwakheka esigabeni of follicle, okuyinto banesibopho ukukhiqizwa kwamaqanda.

Futhi, izidakamizwa ezinqunyiwe njengendlela esikhundleni LH endogenous ngesikhathi sesigaba luteal. Akukhona ukuthi kumane kuqondane ngokuvamile omuhle izidakamizwa "Pregnil" ukubuyekezwa. Eyakhulelwa ngokushesha emva kokwelashwa, uzama ukuncoma imithi nezinye.

Medicine amadoda "Pregnil" kuvusa Leydig amaseli. Ngenxa ukwelashwa esifike ngesikhathi, kungenzeka ukuba kulesetayelekile amazinga testosterone egazini wobulili namandla.

I pharmacokinetics zomuthi

Intaba ephakeme kunazo zonke e-plasma yegazi ngemuva chorionic gonadotropin umjovo ifinyelela amahora ayisishiyagalombili kwabesilisa nabesifazane amahora 20. Kukhona umahluko omkhulu phakathi ukuncela izinto emva umjovo e nabesifazane ezahlukene. Ngo abesifazane, ngesilinganiso lokuhlushwa i-hormone emzimbeni senzeka nge ukubambezeleka. ukusabela okunjalo kuhlanganiswa kakhulu lenyuka adipose izicubu ukujiya emzimbeni.

Cishe ama-80% isidakamizwa wajinge wanamatsela ku izinso. Ngemva kokuba elinye umjovo we ketshezi kuyinto okukhipha amahora 33. Lena yindlela ku kwabesifazane nabesilisa umzimba imithi "Pregnil". Imiyalelo, ukuphawula, umthamo efanele - konke lokhu kwaziswa kufanele ihlolisiswe ngaphambi kokuqala ukwelashwa.

Isikali

Ngemva dilution ukudla okuqinile kuphela kuyadingeka ukwenza phansi kwesikhumba umjovo noma intramuscularly. Ngoba indalo nge-ovulation e ukungazali at ukungezwakali kwawo ngokugcwele noma ukwephulwa nokuvuthwa of follicle kwangena owesifazane kusuka 5000 kuya 10,000 IU "Pregnil" izidakamizwa.

It has a ithuluzi omuhle "Pregnil 5000" ukubuyekezwa. Ubani wakhulelwa, uzama ukudlulisela umyalezo obalulekile ukuba abesifazane okwamanje wazibonela izinjabulo ngumama. Nokho, self-izincomo labangane bahlanganyele engathandeki. Umuthi Kufanele umise uchwepheshe.

Ukuze ekwelapheni ejenti follicle-inkanuko kwanele ukwenza umuntu hlaba "pregna." Izibuyekezo lodokotela abonisa ukuthi umphumela zokwelapha kwenzeka kungakapheli nenyanga. Umuthi iqondiswa ukuba wesibeletho hyperstimulation wokubhoboza ngesikhathi ukudlula uhlelo lokulawula. Ukuze ubambe isigaba luteal lemfundo, kubalulekile ukwenza umjovo endaweni umthamo 1000 kuya ku-3000 IU. Imijovo wenzani ngosuku lwesithathu, lesithupha nangelesishiyagalolunye nge-ovulation eyayenziwe ngamabomu.

Ngo amadoda nge encishisiwe testosterone amazinga emzimbeni umjovo at umthamo we-1000 kuya ku-2000 IU kabili ngesonto. Lapho ukungazali kuyadingeka ukuze ungeze lesi sidakamizwa "Pregnil" izidakamizwa ezengeziwe. Ngokwesibonelo, "Fillitropin" izidakamizwa. Kufanele futhi kwabathinta kabili ngesonto. Inkambo kungathatha izinyanga 3. Kulokhu-ke kuyadingeka ukubala ku ukwanda spermatogenesis. Lapho nokwelapha izidakamizwa "Pregnil" kumelwe ayishiye testosterone replacement therapy.

Isikali ezinganeni

Abafana ngesikhathi ukubambezeleka ukuthomba kusho "Pregnil" ubizwa wangena e umthamo 1500 IU izikhathi ezimbili ngesonto izinyanga eziyisithupha. Ngo ezingaphansi kweminyaka engu-iminyaka engu-2, umuthi iqondiswa ngesikhathi umthamo 250 IU kabili ngesonto amasonto 6. Kufika iminyaka 6, umthamo kuyinto 500-1000 IU. Dechen izinga kungaba ngokwanele eside. Ngemva kweminyaka engu-6, umthamo sifinyelela 1500 IU.

Nge umphumela enganele oqabulayo ukwelashwa Kunconywa ukuphinda.

side effects

Ezimweni ezingavamile kakhulu, ungaqala ukuqubuka generalized noma imfiva. Futhi kukhona ukuphendula wendawo endaweni umjovo. It kubonakala ukuvuvukala, ubuhlungu kanye ukulunywa. Abesifazane musa ngokuvamile ukuthuthukisa thromboembolism emva elungiswa "Pregnil 5000". Izibuyekezo abonisa ukuthi imiphumela emibi yesikhashana futhi siyodlula ngokushesha.

Ezimweni ezingavamile, ukuthuthukisa wesibeletho hyperstimulation syndrome. Gidrotoroks kwenzeka, ubuhlungu besisu nohudo, ukucanuzela kwenhliziyo, webele isisa okuncane kweNdikimba ezikhiqiza amaqanda , futhi izinhlumba. Kwesisindo - omunye uphawu edabukisayo.

Ngo amadoda kanye intsha ekwelapheni kanye ebulilini "Pregnil" ukulungiselela kungenzeka egcina amanzi, kanye sodium emzimbeni. Lokhu kwenzeka ngenxa adrogenov ngokweqile. Kungase kube ukwandisa webele.

Njengoba kungaqondakala, it has eziningi side onweba lesi sidakamizwa "Pregnil". ochwepheshe lezivakashi ukukhombisa ukuthi izimpawu ethulwa akuzona ingozi empilweni. Noma kunjalo, singaqiniseka ukuthi utshele udokotela wakho.

Izimo emithini

Ezinye iziguli zingase ziqale hypersensitivity kuya izidakamizwa izidakamizwa, main "Pregnil" (gonadotropin) noma izakhi zalo osizayo. Awukwazi ukuzinikeza ejenti okusolwa, noma ukuba khona izimila e nabesifazane asebeneminyaka efanele omsakazo ezahlukene.

Ezinganeni ngemithi ukuthomba ekuseni alisetshenziswa. Abesifazane ngesikhathi okungalungile indawo nogwali ukuthuthukiswa, engahambisani sokukhulelwa, njengoba izidakamizwa is contraindicated. Okumele kuqashelwe kudingeka ukuba libhekele ukuthambekela yomzimba thrombosis. Ungayisebenzisi imikhiqizo inhliziyo futhi nokwehluleka ukusebenza kwezinso. Zonke lezi Izimo kufanele kubhekwe ngaphambi kokuqala ukwelashwa nge 'Pregnil ". ochwepheshe lezivakashi basikisela ukuthi umphumela omuhle kuyoba kuphela icala uma isiguli azibambile ukuhlolisisa egcwele emzimbeni.

Uphenyo imithi

Umuthi kunikeza umphumela omuhle ayephuli nokuvuthwa wesibeletho, ukungabi khona nge-ovulation e nenzalo. Abesilisa kanye intsha ngokuqukethwe elincane testosterone njengoba izidakamizwa kwenza kube yi kakhulu zokwelapha.

Izibuyekezo ezingezinhle mayelana imithi nazo ziyatholakala. zihlotshaniswa avame nomuthi okungalungile.

Ngokuvamile omelelwa izindlela asetshenziswa ukwelapha ukungatholi abantwana kwabesifazane. Ngokuvamile, uyakwazi ukuzwa okuhle "Pregnil 5000" libuyekeza izidakamizwa. Ubani wakhulelwa, uyazi ukuthi kubaluleke kangakanani yokwelapha ngesikhathi esifanele.