Ukuhlaziya ebonisa ukuthi 25-OH vitamin D?

Ukuhlolwa kwegazi sokunquma ezingeni vitamin D ezenziwe ukuze sithole abahluphayo umzimba, kanye ukuqapha isimo lesiguli, okuyinto esiqokiwe imithi aqukethe uvithamini asebenzayo. Tadisha enjalo ngasiphi laboratory yezokwelapha, lapho isiguli uzothola umphumela uguqulwa. kokutshelwa ngokukhubazeka kwengane akudingekile, udokotela oqokwe izinkomba ezithile. Lesi sihloko sizosisiza sibheke lokho uvithamini D, izinzuzo zayo ukuze umzimba, kanye indlela sokuhlaziya ukuhlonza saleli vithamini.

mayelana vitamin

Lo msuka wenza ezihlukahlukene imisebenzi. Vitamin D kulawulwa exchange of phosphorus kanye calcium abantu. Phosphorus ukuntula akuyona esongelwa cishe noma ubani, kodwa i-calcium ukuntula iyingozi empilweni. yokuntuleka Namandla vitamin D izingane kungabangela yamathambo e abadala futhi kuholela ithambo ukuthambisa futhi kwengozi waphuka. Lokhu kudala izinkinga emazinyweni. Lo msuka normalizes kwemizwa uhlelo imisebenzi, amaprotheni umzimba, ikhuthaza nokuvuthwa kwamangqamuzana egazi abomvu futhi kwandisa ukumelana ukutheleleka.

Ngaphezu ukusiza ukumuncwa kwe-calcium ne phosphorus, vitamin D kuyalithinta izimiso zomzimba futhi endocrine. Uyakwazi ukuthi "cisha u" futhi "zihlanganisa" 100-1250 20000-30000 zezakhi zofuzo sikhona nakubantu. Njengoba saturation umzimba ngokuvumelana Vitamin encishisiwe ingozi senhliziyo, umdlavuza nezifo sokuhlasela kwamasosha omzimba. Namuhla izifundo ezinkulu ku Vitamin D ewusizo kule ukwelashwa kanye nokuvinjelwa kwezifo ahlukahlukene.

Mhlawumbe ijwayelekile kuwe, ukuthi vitamin D akhiqizwa isikhumba phezu elangeni. Ikakhulukazi it is etholakale ezilwaneni ezithile imikhiqizo yezilwane (isibindi, ingulube, yenkomo ne-cod, mackerel, uwoyela cod kwesibindi, amaqanda isikhuphasha) nemifino (amakhowe ezifana chanterelles amakhowe). By the way, lesi sici is kahle walondoloza ngesikhatsi ukupheka. Zemifino amafutha kanye ezilwane neqhaza nokwenziwa wako umzimba.

Khona-ke, isivele iyasebenza esibindini is kuguquka Vitamin 25-hydroxycholecalciferol, noma 25-OH. Ukukhomba bagcwalisa kahle kanjani ne emzimbeni womuntu, ukuhlaziywa kwenziwa vitamin D (25-OH). Khona-ke 25-hydroxycholecalciferol ku izinso iguqulwe ibe ifomu asebenzayo eyenza omningi walo msebenzi. Ngemva kwezwi vitamin D esikhumbeni asitholayo uguquko isibindi, bese izinso. Okungalapheki isifo sezinso kungabangela nokuntuleka saleli vithamini, ngisho noma okwanele uhlalwe ngabantu elangeni.

Izinzuzo vitamin D izingane, abesilisa nabesifazane

Cishe ingxenye eyodwa kwezintathu abesifazane lapho menopause uhlushwa yokuthi amaminerali leached kusukela amathambo, le nqubo ibizwa ngokuthi osteomalacia. Ngakho, ingozi waphuka kwamathambo.

Amadoda amadala nazo ngaphansi kwamathambo kanye osteomalacia, nakuba kancane ukudlula abantu besifazane. Ngakho-ke, kufanele kudlule yokuhlola Vitamin D 25-OH. Njengoba ukwelashwa kanye nokuvimbela angaqoka ukuthatha kavithamini D. Futhi, ngeminyaka ekhonweni lomzimba lokukwazi synthesize saleli vithamini lapho zihlatshwa yilanga siba sibi.

Ezinye izifundo bonisa iwusizo vitamin D abantu abagulayo kanye psoriasis. Phela, futhi kunciphisa ingozi senhliziyo, izifo sokuhlasela kwamasosha omzimba kanye nomdlavuza.

Ezinganeni-vitamin D kakhulu kubalulekile ekufezeni zokuvimbela yamathambo nezinkinga ngamazinyo. Kodwa ungakhohlwa ukuthi amavithamini D2 futhi D3 akuzona panacea for zonke izifo emhlabeni. Kodwa ukuze sifunde okwengeziwe ngazo awukwazi ubuhlungu.

kwezinkambiso

Vitamin D ngokuvamile atholakala egazini abesifazane abadala futhi amadoda babo bonke ubudala, intsha, izingane kanye nezinsana mayelana efanayo. Kodwa mangisho ukuthi ukusebenza yayo zingahluka ngokuya:

• yobudala (abantu abadala kufanele ezingeni ongaphakeme);
• isizini;
• uhlobo ukudla.

A ukwehla-vitamin D ngesikhathi sokukhulelwa.

Omdala umuntu uthola, lo nzima ke sifinyelele inkomba ejwayelekile uvithamini D, ngenxa yokuguga liwohloka ukukhiqizwa omzimba ngaphansi kwelanga zonke saleli vithamini. Ngenxa sikwazi ukukhuluma sekufanele awushiye ngokungaziniki vitamin D kakhulu eminyakeni yokuguga. Kubantu abadala abathola le mithi kungaba ngisho kuwusizo kakhulu kunokulandela izinsana kanye nabesifazane abakhulelwe. Abantu abamnyama ngubani ziphoqelelwa ukuba ziphile ezweni nge umoya obandayo, liguqubele, ngeke akwenze ngaphandle kokuthatha vitamin D ngefomu ithebhulethi. Phela, lo mnyama umbala, ukwenziwa kwalesi vithamini ukhiqizwa yisikhumba uma engaphansi wadalula UV imisebe.

Ukuhlaziywa ukuze kutholakale izinga vitamin D

Ukuze sithole lokuhlushwa ukuhlaziywa kwenziwa 25-OH (hydroxyl) kavithamini D. Sesiyazi ukuthi ketshezi ekhiqizwa isibindi, bese-ke kufanele sibe izinso, ukuze siguqulwe sibe ifomu asebenzayo.

Lapho shall le ukuhlaziywa? Thatha igazi vitamin D kufanele izikhungo ikakhulu ezikhethekile Endocrinology, plus lokho kungenziwa ngokuthi:

• Ukuhlaziya 25-OH (hydroxyl) vitamin D uphenyo ngokushesha - ezinsukwini ezingu-1-2.
• Ungathola imiphumela nge-imeyili.
• Ukutholakala ubuchwepheshe besimanje ukuqinisekisa ukhululekile igazi izibonelo zalokho.
• Ukuba khona amakamelo ethokomele, uma umoya izihlungi kanye air conditioning, kuhlanganise nokuthi angase TV.
• Ukhululekile isikhathi sokusebenza.

Centres zingakhiqiza ithuba ibhekane ngokuxhumana endocrinology abaqeqeshiwe.

Izinkomba inqubo

Ukuze zihlolelwe 25-OH Vitamin D ukubonakaliswa eyanele yokuntuleka izimpawu isici D emzimbeni, owabonakaliswa ukukhathala yanda, kwehle esesuthi, ukucasuka, tearfulness, futhi ubuthongo ompofu ezinganeni.

Kubandakanya ukuhlaziya wenziwa, uma lokuhlushwa element D luyanda, ukuthi kwenzeka ngenxa nokunwetshiwe ilanga emzimbeni ngoba lokudakwa. Izimpawu lokudakwa Vitamin D - anorexia, i-polyuria, ithambo demineralization, ukuhlanza, hypercalcemia, ukuba buthakathaka kwezicubu nobuhlungu.

I izinkomba esiyinhloko ukulethwa ukuhlaziya:

• Hypovitaminosis D.
• pancreatitis Ezingalapheki, okuyinto kuhambisana esingamahlalakhona secretory.
• Beriberi D.
• Kushisa bhé kule ndawo enteritis.
• osteodystrophy kwezinso.
• isifo Crohn.
• Hypophosphatemia.
• Hypoparathyroidism futhi hyperparathyroidism nge osteomalacia.
• isifo Whipple sika.
• kwamathambo Senile ngenxa ukusetshenziswa corticosteroids.
• kolwelwesi ezingamahlalakhona achlorhydria.
• Hypocalcemia.
• Lupus erythematosus, okuyinto sihlasela kakhulu esikhumbeni.

Kungani lokhu ukuhlaziywa?

Lokhu kuhlaziya kuyadingeka ukunquma degree of lokuhlushwa uvithamini D, okungukuthi, ukuthola hyper- futhi hypovitaminosis D. Abantu abaphethwe izifo ezihlobene iziyaluyalu umzimba ithambo izicubu (kwamathambo noma osteopenia), iphumelele ekuhlolweni phakathi nayo yonke imithi, njengengxenye okunikwa vitamin D ne-calcium. Ukuthunyelwa ukuhlaziywa kudingekile shintsho esifike umthamo futhi zihlole nokufaneleka yokwelapha.

Survey Ukulungiselela

Ukuhlaziya 25-OH vitamin D pass ukudla. Kulokhu, esidlweni sokugcina kumele kwenziwe ku-8, futhi mhlawumbe 12 amahora ngaphambi inqubo. Ngaphambi ngokwedlulele noma yiluphi ucwaningo akuvunyelwe futhi ukuphuza ijusi, itiye nekhofi, ikakhulukazi ushukela, kodwa amanzi okuphuza kungaba elula.

Igazi ethathwa vein ngokusebenzisa cleaner izinhlelo ukuhlinzeka kobuhlungu kocingo impahla. Wayelokhu e kwezimo ezifanele ucwaningo qualitative.

imiphumela yocwaningo

Kuyini izinga ukuhlaziya 25-OH vitamin D? ukuhlaziywa umthetho kumele tisukele 30 kuya ku-100 ng / ml, ukuntuleka - 0-10 ng / ml. Ezinganele Vitamin D kusuka 10 kuya 30 ng / ml. Uma ukusebenza idlula 100 ng / ml, ukudakwa kungenzeka. Kufanele kuqashelwe ukuthi ukuhlaziywa kungcono ukukhetha isikhathi evumayo, okuyinto Uthatha January kuya ku-April. Ngalesi sikhathi, izinga vitamin D aphansi.

Ukuhlolwa kwegazi nesilinganiso kwesinye amayunithi izobukeka kanje:

• Kulungile - 75-250 nmol / l;
• nge ukuntula - 25-75 nmol / l;
• ngesikhathi ukuntula - 0-25 nmol / l;
• lapho ngokweqile - 250 nm nokuningi.

Ingane endocrinology noma udokotela ohlinzayo endocrinology ukulinganisela kubonisa ukuthi ukuhlaziya 25-OH kavithamini D. Igazi iziguli ezine hypoparathyroidism ingaqukatha ngemithamo ezinkulu ngokwengeziwe lapho sithola evamile vitamin D umthamo wansuku zonke, kodwa izinga liyobe mayelana 1250 ng / ml.

Izimbangela evamile vitamin D

Izimo letitsintsa esingamahlalakhona vitamin D:

• isikhathi esichithwa elangeni evulekile;
• ukwehluleka kwezinso;
• Ezinganele engayitholi wezokudla;
• ukuhluleka hepatic;
• yokuntuleka isici E;
• ethola elwa ne-TB izidakamizwa, laxatives futhi barbiturates.

Amazinga aphakeme isici D:

• ukusetshenziswa amalungiselelo equkethe vitamin D okwedlula;
• sarcoidosis;
• hyperparathyroidism;
• ezinye izinhlobo lymphomas;
• engayitholi ongaphakeme calcium ne phosphorus ekudleni.

intengo

Izindleko yokuhlaziya igazi ku-vitamin D kakhulu kungase kuxhomeke indawo yale ndawo kanti futhi lesi sikhungo. Kukhona intengo zingxenye ezilandelayo: 140 k. - Igazi Iqoqo 1600-3200 p. yokuziphatha ucwaningo kwi-vitamin D (kuboniswe izindleko cishe izinqubo).

Lokhu kuhlaziya izophela, futhi umuntu kungekho ubufakazi salokhu, elizovimba ukuthuthukiswa, futhi ukukhomba eziningi izifo e kusaqalwa yabo. Futhi, uyosindisa emiphumeleni ukuthi kungase kwenzeke ngenxa yokugula isikhathi eside.