"Genferon Khanyisa" (spray): yokusetshenziswa, ngempela

Lapho kukhona ukungakhululeki, ngifuna balahle kuye, ngakho search of izidakamizwa ezingaba e esikhathini esifishane ukusiza kulesi simo kudlala indima ebalulekile ukukhethwa zokwelapha. Omunye kusho ukuqalisa ngokushesha kunethonya nomphumela wayo ngemva nokuphathwa sibi izifo zokuphefumula futhi umkhuhlane, umuthi "Genferon Khanyisa" (spray), eliphumelelayo ukwelashwa kanye nokuvimbela imikhuhlane ezibangelwa amagciwane. Lokhu kungenxa uzokhetha indlela yokuphathwa, lapho imithi ilethwa ngqo endaweni ye Isingeniso lwegciwane emzimbeni (esangweni ukutheleleka), kanye nokwakheka kwe-izidakamizwa, okubandakanya interferon kanye taurine.

zokwelapha

Lesi sidakamizwa kungokwalabo iqembu immunomodulators. Siqukethe isakhi sokuzakhela interferon womuntu-alpha-2b, etholwe usebenzisa uhlobo lwama-bacterium Escherichia coli, lapho, isakhi sofuzo by izakhi zofuzo interferon engabantu elifakiwe impahla ukwandisa umzimba ozivikela, futhi taurine kwakwakhe ebangela isenzo elwa namagciwane.

Umuthi liveza isinyathelo eziyinkimbinkimbi:

• immunomodulatory futhi eqabulayo, okungukuthi engavumelana kanye nomsebenzi eqinisa izivikelo somzimba, ebonakaliswa ngenxa alpha-2b-interferon;
• elwa namagciwane, ebonakala abacindezela umsebenzi futhi ikhono nokuzala pathogen endaweni engena emzimbeni;
• antiproliferative, owakhiwa nokucindezela webhaktheriya ukukhula umdlavuza amaseli;
• umlamuleli elwa namagciwane;
• anti-inflammatory.

Nge immunostimulatory nomsebenzi namagciwane izidakamizwa "Genferon Khanyisa" (spray), okuyinto libuyekeza isicelo uqaphele kahle yaso ephezulu nge-SARS, ngemva yethula amavesi acinene ngokushesha uqala ukwenza ezivimbela ukuthuthukiswa ukutheleleka ngesikhathi izigaba zokuqala.

mshini wezenzo

Ukuthola le mucosa we ingaphakathi acinene, umuthi has a wawubona isinyathelo sendawo focus ukutheleleka kanye nomthelela jikelele emzimbeni iyonke.

Mshini jikelele kubangelwa property ezisebenzayo eziqukethwe ukulungiselela "Genferon Khanyisa" (Ikani):

• umthelela namagciwane ngenxa ukusebenza enzyme intracellular ezicindezela ukuphindwaphindwa amagciwane ;
• immunomodulating umsebenzi ngenxa reactivity anda zamabutho mzimba umzimba, okuyinto lihlotshaniswa ukukhuthazwa CD8 T-killer cell, NK amaseli, kwamangqamuzana anda B-lymphocyte futhi ukukhiqizwa kwamasosha omzimba nokuvikeleka yeselula nezinye izimo;
• kwenzeka inkanuko monocyte-macrophage izinhlelo phagocytosis nezinqubo, kanye okwandisa uwukubonakaliswa yamangqamuzana eziyisisekelo eziyinkimbinkimbi obhekene histocompatibility Uhlobo lokuqala (okuyinto kukhulisa ematfuba ukuqashelwa lamaseli onegciwane ngu ejenti esimiso somzimba sokuzivikela ezifweni zomzimba womuntu;
• ukusebenza emangqamuzaneni egazi amhlophe ukuthi kwenzeka ngaphansi isenzo interferon, okuyinto ingxenye izidakamizwa ivumela ukuze sikhuthaze izingqimba zokuzivikela inkonyane mucosa, okuvumela ukuhileleka kwabo ngqo e nokucindezela izilonda;
• ngaphezu kwalokho, ngaphansi kumqhubezela ka interferon womuntu kubuyiselwa ukukhiqizwa isici okufana yokuvikela njengoba secretory immunoglobulin A;
• umphumela ngandlela-thile atholakala elwa namagciwane kukhuliswa ukuzivikela komzimba ukuthi kwenzeka ngenxa ukwethulwa interferon;
• ukuzinza of umzimba izinqubo nokunyusa umthamo okuzivuselela kwezicubu kwenzeka ngaphansi isenzo taurine, nokuba ulwelwesi eliletha ukuthula umsebenzi immunomodulatory;
• taurine, njengoba i antioxidant, kuvimbela ekuqongeleleni-mpilo khulula kwezicubu, okuyinto evimbela ukusabalala izinqubo sokugembula kuzo;
• interferon, ukushintsha izinqubo umzimba kumaseli kulencane ezithwala izifo ezifana amagciwane noma chlamydia, inqubo ungayeka esiphelweni nokusakazwa kwayo.

ukukhululwa Ifomu

Izidakamizwa "Genferon" ikhiqizwa ngesimo suppositories futhi izifutho. Lesi sakamuva uketshezi ukukhanya esobala okuvalelwe ngaphansi kwengcindezi ku amnyama ingilazi isitsha ophela dispenser enikezwe cap zokuzivikela. Okufakiwe ngoba imithamo 100 eliqukethe u-50 000 IU of interferon alfa-2b womuntu isakhi sokuzakhela futhi 0,001 g taurine ngamunye. Yezingxenye ezengeziwe kungenziwa isehlane disodium edetate digidratat, glycerol, dextran, polysorbate, sodium ne -potassium chloride, uwoyela peppermint okumelwe icatshangelwe uma kukhona hypersensitive umuntu yalezi izinto. Suppositories senzelwe abaphathi rectal noma lwesitho sangasese sowesifazane, akhiqizwa imithamo amabili (120 000 noma 250 000 IU), okubenza babe kulungele abadala nezingane, ngokuhambisana isidingo okucatshangelwayo.

izinkomba

Izidakamizwa "Genferon Khanyisa" (fafaza) ikhombisile kusebenta okusezingeni eliphezulu e zokwelapha ukuze ukwelashwa kanye nokuvimbela Umkhuhlane nezinye acute izifo zokuphefumula e abadala kanye nezingane engaphezu kwengu-14, eyenza zikwazi ukuzinqumela bazincome leyo njongo.

Lokhu spray ayikwazi zingabonwa kuphela njengoba ikhambi for umkhuhlane, njengoba usebenza ngezindlela eziyinkimbinkimbi isimo wonke umzimba by ezivimbela ukuphindwaphindwa amagciwane endaweni kokusebenza (mucosa langempela umgudu wokuphefumula), ngaphandle ukuthuthukiswa bamphelezele flora amagciwane by inkanuko umzimba ozivikela umuntu.

Lezo conjoint ivumela izifo eziningi ukuncoma izidakamizwa "Genferon Khanyisa" (spray). Ukufundiswa elikushoyo kahle yaso ephezulu:

• njengendlela yokuthola nokwelapha izifo ezihlukahlukene enobuthi, ikakhulukazi ipheshana zokuphefumula futhi kuvimbele nesenzakalo yabo, ikakhulukazi phakathi kubhubhane;
• njengenhlangano izidakamizwa asizayo sinusitis oyingozi futhi ezingalapheki, ukucinana kwemigudu yokuphefumula, pharyngitis, laryngitis, tracheitis, namathansela nezinye izifo;
• ukubuyisela amasosha omzimba wendawo esikhathini emva kokwelashwa Umkhuhlane nezinye izifo sibi zokuphefumula viral;
• belungiselela ukuhlinzwa yokhetho elingenhla ipheshana zokuphefumula futhi emva kwabo.

Izimo

Izidakamizwa "Genferon Khanyisa" (spray), ukubuyekezwa yokuphathwa ibonisa ukuthi ukucindezelwa ephumelelayo imikhuhlane ngesikhathi kusaqalwa, ingasetshenziswa alulona olwawo wonke umuntu. Musa imnike,

• abantu kokuba ezwela lakhuphuka lafika ku-interferon-alpha-2b, taurine noma ezinye izingxenye ezakha izidakamizwa;
• izingane ezingaphansi kweminyaka engu-engu-14, kusukela spray itholakala kuphela umthamo abadala;
• iziguli nesifo sokuwa noma okunzima isifo senhliziyo.

Iziguli bathambekele ukubukeka acinene ukopha kufanele asebenzise umkhiqizo ngokuqapha.

Ukulungiselela "Genferon Khanyisa" (spray) yokusetshenziswa, umthamo

Lapho ukubonakaliswa izimpawu zokuqala kakhulu lesi sifo udinga ukuqala ukwelashwa nale izidakamizwa. Ukusebenzisa kahle imithetho embalwa okumele ilandelwe:

• emva kokukhipha cap zokuzivikela icindezelwa izikhathi eziningana dispenser kuze izidakamizwa ngxenyana efinyelela lapha (lapho ayisetshenziswa ukuthatha leli isitsha);
• Futha ubambe thwi wokunyathelisa emifushane (1 umthamo isithako esisebenzayo) iqondiswa imithi ikhala badedelane;
• ukuze ugweme ukusabalala ukutheleleka, isitsha ngasinye kumele kusetshenziswe ngamunye.

Ncoma izikimu isicelo ezimbili:

• Ngokusho ngowokuqala, is busuka ikhala of imithi umthamo owodwa ngamunye kathathu ngosuku izinsuku ezinhlanu;
• inketho Okwesibili - isifutho iqondiswa umthamo ngamunye ikhala le 3-4 amahora kuqala, ethula imithi njalo ngemva kwemizuzu engu-20 kulandele izidakamizwa ekuphathweni 3-4 izinsuku kuze kube izikhathi 5 ngosuku.

Umkhawulo ovumelekile lemali nsuku zonke izidakamizwa 10 Ukweqiwa.

Izidakamizwa "Genferon Khanyisa" (spray): Yokusetshenziswa izingane

immunomodulator Active akhiqizwa amafomu amabili Isikali - njengendlela suppositories rectal kokuba okuqukethwe okuhlukile lomcebo asebenzayo ngesimo isifutho. Ithola okuqukethwe izisekelo izidakamizwa ukuqokwa izidakamizwa ezinganeni. Amakhandlela ekhiqizwa ngemithamo ezimbili: okuqukethwe 250,000 IU of interferon alfa-2b, okuyinto ezinqunyiwe abadala nezingane ezingaphezulu kuka-7 ubudala, futhi umthamo 125.000 ME, ukusetshenziswa okuyinto kungenzeka ngisho ekwelapheni neonates. Imiyalelo sivimbela ukusetshenziswa "Genferon Khanyisa" umkhiqizo (spray) izingane. Izibuyekezo uqaphele ukusebenza ezinhle suppositories ngoba impatho eyinkimbinkimbi SARS, izifiso eziningi ukubonakaliswa ukubukeka isifutho izingane njengoba kulula ukusebenzisa. Ngesikhathi esifanayo it ovunyelwe ukhombe kuphela lapho ingane ifinyelela eminyakeni yobudala engu-14.

Sebenzisa ekukhulelweni

Isimo olukhethekile umzimba female, ezihambisana nengane esindayo ingane, kudinga indlela ngokucophelela kukhethwa izidakamizwa, njengoba abaningi babo contraindicated ngokuphelele umama okhulelwe, noma kusetshenziswe ngokuqapha, uma inzuzo kulindeleke idlula ingozi embungwini. Sebenzisa lesi sidakamizwa "Genferon Khanyisa" (spray) ngesikhathi sokukhulelwa kuvunyelwe kunoma yisiphi isigaba, kusukela izifundo Akabonisanga imiphumela emibi lesi izidakamizwa embungwini. Kunalokho, basengozini enkulu yokutheleleka (isibonelo, inkathi yokugula anda noma ukuxhumana evele isigula) umama okhulelwe Kunconywa ukusebenzisa lolu spray njengoba isilinganiso prophylactic. Lokhu kungenxa yokuthi isidumbu abakhulelwe usengozini yokuthola imikhuhlane ngenxa kwezintela imbangela ukumelana layo nezici eziyingozi.

Ukusebenzisa spray ngesikhathi ibele

Ukuvinjelwa ukusetshenziswa izinhlobo ezihlukahlukene zezindwangu ezingaba izidakamizwa ngesikhathi ibele kungenxa yokuthi isithako esebenzayo lingena singene ubisi lwebele futhi kungenzeka ungene isidumbu sengane, okuyinto iyingozi ikakhulu uma ekutholeni izimali alinikeziwe izinsana. Ukulungiselela "Genferon Khanyisa" (spray) I-lactation ingasetshenziswa, njengoba akusho angena kulo isithiyo mammary nezindlala. Ngakolunye uhlangothi, ukukhuthazwa amabutho ayisivikelo umama ngokungaqondile kuthuthukisa isimiso somzimba sokuzivikela kanti ingane. Ngaphezu kwalokho, nakuba izidakamizwa "Genferon" ngesimo isifutho izingane ezingaphansi kweminyaka 14 awaboniswa (kuphela ngenxa "omdala" nokushintsha kokudla nokufakwa), suppositories eliqukethe ketshezi ovunyelwe zisebenze isikhathi ezisanda kubelethwa lapho izifo eziningi ezibangelwa amagciwane.

isicinganani

Odokotela abaningi batusa njengoba isilinganiso izifo "Genferon Khanyisa" (spray). Yokusetshenziswa hhayi uqaphele ethize side effects kusukela ukusetshenziswa kwayo. Ngezikhathi ezithile kungenzeka izenzakalo ayisibonelo salezi yiluphi uhlobo interferon alfa-2b, owabonakaliswa Ukugodola, imfiva, ukukhathala, ukungakuthandi ukudla, muscle and ikhanda, ukujuluka. imiphumela olunje ngokuyinhloko ukukhishwa phezu 10000000 IU ngosuku. Livela okunjena kudinga ngokuxhumana udokotela on ukukhethwa omunye umthamo umuthi.

Ukuhambelana nabanye ukuthaka imithi ngendlela

Mayelana nokuxhumana nezinye izinto "Genferon Khanyisa" izidakamizwa (spray acinene) imfundo isicelo akukuniki isiqondiso kakhulu. Nge leli fomu Isikali kukhona iyahambisana cishe nawo wonke imithi. Isimo kuphela akwamukeleki nhlobo ukuphatha ngesikhathi esisodwa ekhaleni amathonsi senzelwe ekulweni catarrhal izinqubo ingaphakathi acinene kanye izidakamizwa, okuyinto kunganciphisa ukusebenza kwabo. Ngakho-ke, ukusetshenziswa kwalezi izidakamizwa kudingeka iqembu, ngokuqaphela nokugcina isimiso yokuphathwa ehlukile.

Izibuyekezo

Iziguli eziningi ziphathwe izidakamizwa "Genferon Khanyisa" (spray), uthi mayelana ukusebenza yayo okusezingeni eliphezulu e ezivimbela izifo ezibangelwa amagciwane kanye ukungabikho side effects kanye nokuhlukumezeka yokusetshenziswa kwawo. ukuqala Early yokusetshenziswa (ngesikhathi izimpawu zokuqala kakhulu lesi sifo) kuzovikela ukuthuthukiswa izifo kanye yokulicindezela ngokushesha ngangokunokwenzeka. Njengoba iphuzu elilodwa yokungabi bikho izidakamizwa acinene izingane ezingaphansi kweminyaka engu-14, njengoba izidakamizwa "Genferon Khanyisa" kuleli qembu yobudala, njengoba kushiwo ngenhla, ukhona kuphela ngesimo suppositories. Lokhu kungadala ukwenqaba lolu hlobo yokwelapha seziguli ezisencane.

Ngakho, ukubukeka noma iziphi izimpawu ukuthuthukiswa Umkhuhlane noma ezinye acute nezifo zokuphefumula batusa ukusetshenziswa ukulungiselela ngokushesha "Genferon Khanyisa" (acinene spray), namagciwane kokuba, emnandi omzimba bese isenzo modulating, nomphumela eqeda ukuvuvukala, okuzokwenza ukucindezela okwenzeka isifo ekuqaleni futhi susa konke yezimpawu ezibonakala esikhathini esifushane. Administration isidakamizwa ukundlula isimiso sokugaya ukudla bungene kuyivumela, kungakhathaliseki ukuthi ukudla noma nini, nganoma isithako efanayo esebenzayo ngokugcwele ngangokunokwenzeka futhi wafunda ngokushesha ku isayithi umjovo. ukusetshenziswa Intranasal ikhuthaza Ukungena zomuthi ngqo Locus (kusukela igciwane lohlobo idluliselwa ngokuyinhloko droplet ukutheleleka) bembonisa umphumela wawo kuzo ngaphakathi ezweni nakumazwe ngokuvamile wonke umzimba, okuyinto kubangelwa ukumuncwa olulinganiselwe izidakamizwa egazini ngokusebenzisa ulwelwesi lwamafinyila we acinene uhamba.