I-hormone estradiol: izinga kwabesifazane. Estradiol: ngesilinganiso sokukhulelwa

Umzimba womuntu - kwakha isimiso esiyinkimbinkimbi, ukusebenza okuyinto kakhulu kuthinta hormone. Lezi izinto eziphila abakhuthele ezivezwa amaseli nezindlala endocrine. Bangenela egazini kuthinte umzimba futhi umsebenzi izitho zangaphakathi. Ububi lezi zakhi zingaphazamisa ukusebenza kwe-izinhlelo ezihlukahlukene zomzimba. I ebaluleke kakhulu umsebenzi zokuzala kubhekwa wobulili i-hormone estradiol. Norma abesifazane lokhu ezibonakalayo kuphela uqinisekisa kabusha umntwana ophile, kodwa futhi lilolonge ngokubukeka kwabo.

Kuyini estradiol

Lena ngenye yezindlela ezibaluleke kakhulu hormone, elingelakwaJuda iqembu estrogen. Ngaphansi ithonya lakhe, abesifazane kwakheka lonke uhlelo zokuzala kanye izitho zangaphakathi ukuthi banesibopho umsebenzi zokuzala. Ngaphandle lokhu isithako unesibopho wabuka oyindilinga izibalo nabobulili fair, ukukhula webele, ilawula sebethule fat ongama ku esiswini namathanga. Hormone inomthelela ezingeni isifiso sobulili, Ubumnene, izintokazi, ulawula umjikelezo wokuya esikhathini.

Yini sezindawo

I-hormone estradiol besifazane uyakwazi ukuthuthukisa igazi ligeleze kwesibeletho, ngiyoba nethonya elihle esimweni izitsha. izidakamizwa Active possesses:

• umphumela steroid.
• It ngesivinini inqubo Iqanda nokuvuthwa.
• Kwandisa umzimba e bone izicubu.
• Sodium namanzi nokugcinwa emzimbeni.
• Kwehlisa cholesterol.
• It kwandisa igazi ekunqandeni.

Estradiol ikhuthaza ukukhululwa kwe neurotransmitters ezinciphisa ukucasuka futhi kuvimbele overexcitement sezinzwa. zisesimweni esikahle kwesikhumba, akukho imibimbi, kukhanye kwamehlo, nentshiseko nomdlandla, ukukhuthazela ngokomzimba - zonke lezi zici ukuqinisekisa izinga evamile estradiol egazini. Izinga eliphakeme le-hormone siyenzeka phakathi amahora 15-18., Futhi kulencane ikhishwe kwenzeka nge 24 h. Ukuze 2 amahora. Ngokuphazima kweso.

Norm i-hormone emzimbeni yabesifazane

I lokuhlushwa estradiol egazini uyakwazi ziyahlukahluka kuye isimo somzimba wesifazane esikhathini umjikelezo wokuya esikhathini. Encwadini amazinga umzimba izintokazi ubulili i-hormone enempilo ukuba kwehliswe ngesikhathi isigaba follicular lomjikelezo. Cishe 3-6 izinsuku ngaphambi okwandisa pituitary i-hormone (LH) iqala ukwandisa futhi amazinga estradiol, okuyinto izinga inyuka ngokucijile futhi ifinyelela esiphezulu ihora elilodwa ngaphambi isiqongo LH.

emva kwezinsuku ezimbalwa emakamu esiphezulu luteinizing i-hormone uqala wehlise ngokucijile inkomba estradiol ke liyaphuma futhi kancane kancane. It ifinyelela omunye esiphezulu ngosuku 9 emva nge-ovulation. Kodwa uma bekhulelwe lwenzeke, ezingeni lomcebo asebenzayo iqala ukunqabela futhi ufinyelele wemithetho.

okutholakele laboratory

Kubalulekile kakhulu zonke ntombazane ukuqhuba gqwa ucwaningo ezingeni amahomoni main. Livela izifo eziningi, ukuphazamiseka izibilini eziyimbangela yezinkinga ezizuzwa kwesimiso sokuzala - zonke lezi zinkinga kungabangela eliphezulu kakhulu noma eliphansi i-hormone estradiol. Sivamile nabesifazane abangenazo azalele yilesi:

• isigaba Follicular - amazinga isukela 57 227 pmol / L e-plasma.
• isiqongo Preovulatory - ivela 127 kuya 476 pmol / l.
• isigaba Luteal - izinga kusuka 77 kuya 227 pmol / l.

Kufanele kuqashelwe ukuthi abesifazane (ukuya esikhathini), lezi zibalo ephansi kakhulu.

Hormone eyinhloko sokukhulelwa

Njengoba odokotela, akunakwenzeka ukuba azalele ezingeni ukuncipha estradiol. Ngempela, ngale nkathi, i-hormone kufanele babekhona emzimbeni ngesilinganiso esiphezulu: incike kumiswa lesifanele yomzanyana kunomthelela ukuthuthukiswa kanye nokukhula kwesibeletho, futhi normalizes kwegazi ezithweni kwezitho zangasese. Ngaphezu kwalokho, uyena obangela evamile igazi ekunqandeni ngesikhathi sokubeletha, ukuhlinzeka ingozi sakugcina ukopha. Kodwa amazinga aphansi kwezinto eziphilayo kungaholela kwesisu, ikakhulukazi sokukhulelwa ekuseni. Ngakho, ama-hormone estradiol - sokukhulelwa ovamile:

• 3-6 amasonto - 0.5-4.0.
• 7-8 - 4.0-7.5.
• 9-10 - 7.5-8.5.
• 11-12 - 8,5-10,9.
• 13-14 - 10,5-12,0.
• 15-16 - 12,0-21,5.
• 17-18 - 21,5-29,0.
• 19-20 - 29,0-37,0.
• 21-22 - 37.0-38.0.
• 23-24 - 38,0-42,0.
• 25-26 - 42,0-45,0.
• 27-28 - 45,0-50,0.
• 29-30 - 50,0-52,0.
• 31-32 - 52,0-55,0.
• 33-34 - 55,0-57,2.
• 35-36 - 57,5-59,0.
• 37-38 - 59,0-61,0.
• 39-41 - 61,0-66,0.

Odokotela batusa ukuba sihlale njalo siqaphele izinga lama-hormone ngesikhathi sokukhulelwa.

Kanjani ukuba bahlolelwe

Njengoba odokotela abathi izidakamizwa Iqembu lesibili ezibalulekile estrogen ngabesifazane yokuma hormone estradiol. Norma sokukhulelwa we ketshezi kufanele sifakwe kuhambisana le mithetho:

• isimo esijwayelekile ngokomzwelo - akuvunyelwe ukuba sihlaziye esimweni overstrain sezinzwa noma hyperexcitability.
• Anikwazi ukuphuza utshwala intuthu.
• Ngolunye usuku ngaphambi cwaningo ukuqeda ukucindezeleka okungokomzimba bayaya ocansini.
• Qasha ukuhlaziywa esiswini esingenalutho ekuseni ngaphambi kwesidlo.

Ngokulandela leyo mithetho, ungathola i test yi olunembile, kodwa uma ungazange athobele noma uthathe noma imithi, kufanele wazise udokotela.

Yini enquma ezingeni le-hormone egazini

Kubalulekile ukwazi ukuthi kungani ketshezi asebenzayo kwandisa lokuhlushwa yayo egazini. Lezi zinombolo zibonisa khona lezi zinto ezilandelayo:

• Aphikelele follicle.
• Izinhlumba e esibelethweni uhlamvu endometrioid.
• izimila ezahlukene wesibeletho.
• Isifo sokusha.
• Ukuthola imithi phenytoin, ketoconazole, mifepristone, nafarelin, estrogens.

Estradiol komzimba lingaphansi kunalokhu okujwayelekile kwabesifazane kungadalwa izinto ezifana:

• Hypogonadism.
• ukubhasha komzimba pituitary.
• Giperprolaktinimiya.
• Esingamahlalakhona yesigaba luteal.
• Virilnoe syndrome.
• Turner Syndrome.
• ukuvuvukala Okungalapheki izitho zangasese yangaphakathi.
• Usongo lwezigebengu yisisu.
• Ukubhema kwabesifazane abakhulelwe.

Kwezinye izimo, lo lokuhlushwa i-hormone incipha ngenxa bandisa inkonzo ngokomzimba, okusheshayo kwesisindo, ngokungabi bikho amafutha ekudleni, imifino. Izimpawu amazinga aphansi estradiol kukhona isikhumba esomile, njalo umjikelezo wokuya esikhathini, noma ukungezwakali kwawo, isikhathi eside uzokhulelwa, webele ukunciphisa. Ngakho-ke kubalulekile uma uhlela ukukhulelwa ukuqapha igazi i-hormone estradiol. Norma abesifazane yalolu ketshezi kuzoqinisekisa hhayi kuphela nje ebamba isisu ephephile, kodwa futhi ukwandisa amathuba okukhulelwa yimpumelelo futhi ukulethwa ekukhanyeni kukamama esizayo.

imithi

Uma ucwaningo isethwe amazinga estradiol ephansi, udokotela angase anikeze isiguli imithi aqukethe yalolu ketshezi. Abenzi kuphela ukusiza ukubuyisela menstrual cycle evamile, kodwa futhi wabonisa ngoba amaqanda polycystic, sangasese, ukungazali, ubuthakathaka ngenxa yokuzalwa, lapho sokukhulelwa okuthunyelwe eside, ngoba lactation ukucindezelwa emva kokubelethwa, hypertrichosis lapho virial. ukuthaka imithi akhishwa ezihlukahlukene: amaphilisi, si, transdermal, izixazululo esicutshini, izifutho acinene, transdermal izinhlelo ezelaphayo. Khumbula, udokotela kuphela angakunika umuthi ukwelashwa okufanelekile! Kuye ukusetshenziswa ngabanye:

• "Estrofem" amaphilisi-mbumbulu.
• "Proginova" gel.
• Ukufakwa "Estraderm TTS 25".
• "Estradiol" gel.

Ngemva ahlolwe kahle emzimbeni izifo zabesifazane inikezwa yokwelapha, kuthatha isikhathi eside. Impatho enjalo kungaba ngcono umzimba sika-hormone okuthiwa i estradiol. Norma abesifazane yalolu ketshezi kubalulekile ukusebenza evamile uhlelo zokuzala kanye nokukhulelwa.